Zobrazeno 1 - 10
of 87
pro vyhledávání: '"Derek A, Oldridge"'
Autor:
Arash Nabbi, Pengbo Beck, Alberto Delaidelli, Derek A. Oldridge, Sumedha Sudhaman, Kelsey Zhu, S. Y. Cindy Yang, David T. Mulder, Jeffrey P. Bruce, Joseph N. Paulson, Pichai Raman, Yuankun Zhu, Adam C. Resnick, Poul H. Sorensen, Martin Sill, Sebastian Brabetz, Sander Lambo, David Malkin, Pascal D. Johann, Marcel Kool, David T. W. Jones, Stefan M. Pfister, Natalie Jäger, Trevor J. Pugh
Publikováno v:
Genome Medicine, Vol 15, Iss 1, Pp 1-24 (2023)
Abstract Background Cancer immunotherapies including immune checkpoint inhibitors and Chimeric Antigen Receptor (CAR) T-cell therapy have shown variable response rates in paediatric patients highlighting the need to establish robust biomarkers for pa
Externí odkaz:
https://doaj.org/article/55f18503cc5b446bb5969c8df01fb686
Autor:
Jonathan Sussman, Abigail M Zellmer, Amy E Baxter, Rami S Vanguri, Kyung Jin Ahn, Arianne Parvaresh-Rizi, Anusha Thadi, Chia-hui Chen, Wenbao Yu, Kristina Cole, Kai Tan, Derek A Oldridge
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 2 (2023)
Externí odkaz:
https://doaj.org/article/280c369007684cd08ece268e9756499c
Autor:
Nina Weichert-Leahey, Hui Shi, Ting Tao, Derek A. Oldridge, Adam D. Durbin, Brian J. Abraham, Mark W. Zimmerman, Shizhen Zhu, Andrew C. Wood, Deepak Reyon, J. Keith Joung, Richard A. Young, Sharon J. Diskin, John M. Maris, A. Thomas Look
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 10 (2023)
Childhood neuroblastomas exhibit plasticity between an undifferentiated neural crest–like mesenchymal cell state and a more differentiated sympathetic adrenergic cell state. These cell states are governed by autoregulatory transcriptional loops cal
Externí odkaz:
https://doaj.org/article/26b30da61a8a4fd2905ae5306aa93199
Autor:
Caroline Diorio, Rawan Shraim, Laura A. Vella, Josephine R. Giles, Amy E. Baxter, Derek A. Oldridge, Scott W. Canna, Sarah E. Henrickson, Kevin O. McNerney, Frances Balamuth, Chakkapong Burudpakdee, Jessica Lee, Tomas Leng, Alvin Farrel, Michele P. Lambert, Kathleen E. Sullivan, E. John Wherry, David T. Teachey, Hamid Bassiri, Edward M. Behrens
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Multi-inflammatory syndrome in children (MIS-C) can be associated with SARS-CoV-2 infection but can also be similar to other inflammatory syndromes. Here the authors characterise the plasma proteome phenotype in MIS-C and compare to other SARS-CoV-2
Externí odkaz:
https://doaj.org/article/a888480056e0487995e0516acf1b06ce
Autor:
Carter Merenstein, Guanxiang Liang, Samantha A. Whiteside, Ana G. Cobián-Güemes, Madeline S. Merlino, Louis J. Taylor, Abigail Glascock, Kyle Bittinger, Ceylan Tanes, Jevon Graham-Wooten, Layla A. Khatib, Ayannah S. Fitzgerald, Shantan Reddy, Amy E. Baxter, Josephine R. Giles, Derek A. Oldridge, Nuala J. Meyer, E. John Wherry, John E. McGinniss, Frederic D. Bushman, Ronald G. Collman
Publikováno v:
mBio, Vol 13, Iss 5 (2022)
Externí odkaz:
https://doaj.org/article/4210de6591cd4fcdb3d6cb3838f991b6
Publikováno v:
Journal of Orthopaedic Translation, Vol 27, Iss , Pp 110-118 (2021)
Background: Distraction osteogenesis (DO) is a functional tissue engineering approach that applies gradual mechanical traction on the bone tissues after osteotomy to stimulate bone regeneration. However, DO still has disadvantages that limit its clin
Externí odkaz:
https://doaj.org/article/4b68bc27640243e0b0aa76eda05c0822
Autor:
Yuki Muroyama, Hiroyuki Tamiya, Goh Tanaka, Wakae Tanaka, Alexander C. Huang, Derek A. Oldridge, Keisuke Matsusaka, Yutaka Takazawa, Taisuke Jo, Tetsuo Ushiku, Takahide Nagase
Publikováno v:
Case Reports in Oncology, Vol 13, Iss 3, Pp 1552-1559 (2020)
Lung hepatoid adenocarcinoma (HAC) is a rare primary lung carcinoma pathologically characterized by hepatocellular carcinoma-like tumor cells, the majority of which produce alpha-fetoprotein (AFP). The clinical prognosis of lung HAC is generally poor
Externí odkaz:
https://doaj.org/article/39a8b37f0df34594b1086284b121ee1a
Autor:
Sokratis A. Apostolidis, Amrita Sarkar, Heather M. Giannini, Rishi R. Goel, Divij Mathew, Aae Suzuki, Amy E. Baxter, Allison R. Greenplate, Cécile Alanio, Mohamed Abdel-Hakeem, Derek A. Oldridge, Josephine R. Giles, Jennifer E. Wu, Zeyu Chen, Yinghui Jane Huang, Jonathan Belman, Ajinkya Pattekar, Sasikanth Manne, Oliva Kuthuru, Jeanette Dougherty, Brittany Weiderhold, Ariel R. Weisman, Caroline A. G. Ittner, Sigrid Gouma, Debora Dunbar, Ian Frank, Alexander C. Huang, Laura A. Vella, The UPenn COVID Processing Unit, John P. Reilly, Scott E. Hensley, Lubica Rauova, Liang Zhao, Nuala J. Meyer, Mortimer Poncz, Charles S. Abrams, E. John Wherry, Sharon Adamski, Zahidul Alam, Mary M. Addison, Katelyn T. Byrne, Aditi Chandra, Hélène C. Descamps, Nicholas Han, Yaroslav Kaminskiy, Shane C. Kammerman, Justin Kim, Jacob T. Hamilton, Nune Markosyan, Julia Han Noll, Dalia K. Omran, Eric Perkey, Elizabeth M. Prager, Dana Pueschl, Austin Rennels, Jennifer B. Shah, Jake S. Shilan, Nils Wilhausen, Ashley N. Vanderbeck
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Patients with COVID-19 present with a wide variety of clinical manifestations. Thromboembolic events constitute a significant cause of morbidity and mortality in patients infected with SARS-CoV-2. Severe COVID-19 has been associated with hyperinflamm
Externí odkaz:
https://doaj.org/article/f380b6f884834140a346b9249d88cbb6
Autor:
Carter Merenstein, Guanxiang Liang, Samantha A. Whiteside, Ana G. Cobián-Güemes, Madeline S. Merlino, Louis J. Taylor, Abigail Glascock, Kyle Bittinger, Ceylan Tanes, Jevon Graham-Wooten, Layla A. Khatib, Ayannah S. Fitzgerald, Shantan Reddy, Amy E. Baxter, Josephine R. Giles, Derek A. Oldridge, Nuala J. Meyer, E. John Wherry, John E. McGinniss, Frederic D. Bushman, Ronald G. Collman
Publikováno v:
mBio, Vol 12, Iss 4 (2021)
ABSTRACT Viral infection of the respiratory tract can be associated with propagating effects on the airway microbiome, and microbiome dysbiosis may influence viral disease. Here, we investigated the respiratory tract microbiome in coronavirus disease
Externí odkaz:
https://doaj.org/article/ca5cad2815fe4e0a812dfa0c43ae79ec
Autor:
Vinodh Pillai, Kavitha Muralidharan, Wenzhao Meng, Asen Bagashev, Derek A. Oldridge, Jaclyn Rosenthal, John Van Arnam, Jos J. Melenhorst, Diwakar Mohan, Amanda M. DiNofia, Minjie Luo, Sindhu Cherian, Jonathan R. Fromm, Gerald Wertheim, Andrei Thomas-Tikhonenko, Michele Paessler, Carl H. June, Eline T. Luning Prak, Vijay G. Bhoj, Stephan A. Grupp, Shannon L. Maude, Susan R. Rheingold
Publikováno v:
Blood Advances, Vol 3, Iss 22, Pp 3539-3549 (2019)
Abstract: Tisagenlecleucel, a chimeric antigen receptor (CAR) T-cell product targeting CD19 is approved for relapsed/refractory B-cell acute lymphoblastic leukemia (B-ALL). However, the impact of pretreatment variables, such as CD19 expression level,
Externí odkaz:
https://doaj.org/article/e70ab1bdc076485da3ba01a3a1e59b84