Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Derek Britain"'
Autor:
David Mavor, Kyle A. Barlow, Daniel Asarnow, Yuliya Birman, Derek Britain, Weilin Chen, Evan M. Green, Lillian R. Kenner, Bruk Mensa, Leanna S. Morinishi, Charlotte A. Nelson, Erin M. Poss, Pooja Suresh, Ruilin Tian, Taylor Arhar, Beatrice E. Ary, David P. Bauer, Ian D. Bergman, Rachel M. Brunetti, Cynthia M. Chio, Shizhong A. Dai, Miles S. Dickinson, Susanna K. Elledge, Cole V. M. Helsell, Nathan L. Hendel, Emily Kang, Nadja Kern, Matvei S. Khoroshkin, Lisa L. Kirkemo, Greyson R. Lewis, Kevin Lou, Wesley M. Marin, Alison M. Maxwell, Peter F. McTigue, Douglas Myers-Turnbull, Tamas L. Nagy, Andrew M. Natale, Keely Oltion, Sergei Pourmal, Gabriel K. Reder, Nicholas J. Rettko, Peter J. Rohweder, Daniel M. C Schwarz, Sophia K. Tan, Paul V. Thomas, Ryan W. Tibble, Jason P. Town, Mary K. Tsai, Fatima S. Ugur, Douglas R. Wassarman, Alexander M. Wolff, Taia S. Wu, Derek Bogdanoff, Jennifer Li, Kurt S. Thorn, Shane O'Conchúir, Danielle L. Swaney, Eric D. Chow, Hiten D. Madhani, Sy Redding, Daniel N. Bolon, Tanja Kortemme, Joseph L. DeRisi, Martin Kampmann, James S. Fraser
Publikováno v:
Biology Open, Vol 7, Iss 7 (2018)
Although the primary protein sequence of ubiquitin (Ub) is extremely stable over evolutionary time, it is highly tolerant to mutation during selection experiments performed in the laboratory. We have proposed that this discrepancy results from the di
Externí odkaz:
https://doaj.org/article/120375a9425d4b15800ba82e59af4543
Autor:
Rachel M. Brunetti, Gabriele Kockelkoren, Preethi Raghavan, George R.R. Bell, Derek Britain, Natasha Puri, Sean R. Collins, Manuel D. Leonetti, Dimitrios Stamou, Orion D. Weiner
Publikováno v:
Brunetti, R M, Kockelkoren, G, Raghavan, P, Bell, G R R, Britain, D, Puri, N, Collins, S R, Leonetti, M D, Stamou, D & Weiner, O D 2022, ' WASP integrates substrate topology and cell polarity to guide neutrophil migration ', Journal of Cell Biology, vol. 221, no. 2, e202104046 . https://doi.org/10.1083/jcb.202104046
The Journal of cell biology, vol 221, iss 2
The Journal of cell biology, vol 221, iss 2
To control their movement, cells need to coordinate actin assembly with the geometric features of their substrate. Here, we uncover a role for the actin regulator WASP in the 3D migration of neutrophils. We show that WASP responds to substrate topolo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::737b4acf3174f8324ab190368a42c1fc
https://curis.ku.dk/ws/files/309279317/jcb_202104046.pdf
https://curis.ku.dk/ws/files/309279317/jcb_202104046.pdf
Autor:
Orion D. Weiner, Derek Britain
T cells use kinetic proofreading to discriminate antigens by converting small changes in antigen binding lifetime into large differences in cell activation, but where in the signaling cascade this computation is performed is unknown. Previously, we d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c7b12312c125bc86b0114d4462f8241
https://doi.org/10.1101/2021.11.10.468056
https://doi.org/10.1101/2021.11.10.468056
Publikováno v:
Biointerphases
The need for direct biomaterial-based delivery of growth factors to wound surfaces to aid in wound healing emphasizes the importance of interfacial interactions between the biomaterial and the wound surface. These interactions include the spatial loc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b6fede0ade378b4ee68069663900416
https://europepmc.org/articles/PMC6905652/
https://europepmc.org/articles/PMC6905652/
Autor:
Danielle L. Swaney, Alexander M. Wolff, Tamas L. Nagy, Douglas Myers-Turnbull, Douglas R. Wassarman, Kyle A. Barlow, Paul V. Thomas, Rachel M. Brunetti, Derek Britain, Kevin Lou, Sy Redding, Wesley M. Marin, Mary K. Tsai, Kurt S. Thorn, Ryan W. Tibble, Lillian R. Kenner, Daniel M. C. Schwarz, Charlotte A. Nelson, Bruk Mensa, Fatima S. Ugur, Derek Bogdanoff, Taia S. Wu, E. Kang, Nicholas J. Rettko, Leanna S. Morinishi, Peter F. McTigue, Martin Kampmann, Gabriel K. Reder, Eric D. Chow, Alison M Maxwell, Jason Town, James S. Fraser, Andrew M. Natale, David P. Bauer, Cole Helsell, Joseph L. DeRisi, Yuliya Birman, Pooja Suresh, Evan M. Green, Ruilin Tian, Jennifer Y. Li, Sergei Pourmal, Weilin Chen, Hiten D. Madhani, Daniel N. Bolon, Miles Sasha Dickinson, Shane O’Conchúir, Keely Oltion, Daniel Asarnow, Peter J. Rohweder, Susanna K. Elledge, David Mavor, Erin M. Poss, Matvei S. Khoroshkin, Beatrice Ary, Ian D. Bergman, Nadja Kern, Taylor Arhar, Lisa L. Kirkemo, Tanja Kortemme, Sophia K. Tan, Shizhong Dai, Greyson R. Lewis, Nathan L. Hendel, Cynthia M. Chio
Publikováno v:
Biology Open
Biology open, vol 7, iss 7
Biology Open, Vol 7, Iss 7 (2018)
Mavor, D; Barlow, KA; Asarnow, D; Birman, Y; Britain, D; Chen, W; et al.(2018). Extending chemical perturbations of the ubiquitin fitness landscape in a classroom setting reveals new constraints on sequence tolerance. BIOLOGY OPEN, 7(7). doi: 10.1242/bio.036103. UCSF: Retrieved from: http://www.escholarship.org/uc/item/2hz894gr
Biology open, vol 7, iss 7
Biology Open, Vol 7, Iss 7 (2018)
Mavor, D; Barlow, KA; Asarnow, D; Birman, Y; Britain, D; Chen, W; et al.(2018). Extending chemical perturbations of the ubiquitin fitness landscape in a classroom setting reveals new constraints on sequence tolerance. BIOLOGY OPEN, 7(7). doi: 10.1242/bio.036103. UCSF: Retrieved from: http://www.escholarship.org/uc/item/2hz894gr
Although the primary protein sequence of ubiquitin (Ub) is extremely stable over evolutionary time, it is highly tolerant to mutation during selection experiments performed in the laboratory. We have proposed that this discrepancy results from the di
Autor:
Nadja Kern, Taylor Arhar, Matvei S. Khoroshkin, Ian D. Bergman, Lisa L. Kirkemo, Danielle L. Swaney, Nathan L. Hendel, Jason Town, Weilin Chen, Lillian R. Kenner, Alexander M. Wolff, Wesley M. Marin, Rachel M. Brunetti, Charlotte A. Nelson, Susanna K. Elledge, Sergei Pourmal, Greyson R. Lewis, Cynthia M. Chio, Derek Britain, Derrick Bogdanoff, Andrew M. Natale, Shane O’Conchúir, Martin Kampmann, Douglas R. Wassarmann, Kyle A. Barlow, Bruk Mensa, Gabriel K. Reder, Kurt S. Thorn, Ryan W. Tibble, Pooja Suresh, Sy Redding, Keely Oltion, Tanja Kortemme, James S. Fraser, Daniel Asarnow, Evan M. Green, Fatima S. Ugur, David L.V. Bauer, Sophia K. Tan, Joseph L. DeRisi, Beatrice Ary, Yuliya Birman, Tamas L. Nagy, Daniel N. Bolon, Miles Sasha Dickinson, Taia Wu, K. Tsai, Peter F. McTigue, Ruilin Tian, Nicholas J. Rettko, Shizhong Dai, Hiten D. Madhani, Jennifer Y. Li, Douglas Myers-Turnbull, Kevin Lou, Peter J. Rohweder, David Mavor, Daniel M. C. Schwarz, Alison M Maxwell, Erin M. Poss, Cole Helsell, E. Kang, Leanna S. Morinishi, Paul Thomas, Eric D. Chow
Although the primary protein sequence of ubiquitin (Ub) is extremely stable over evolutionary time, it is highly tolerant to mutation during selection experiments performed in the laboratory. We have proposed that this discrepancy results from the di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::beb1693458a8341e04b43f423acafd0d
Publikováno v:
Lab on a chip. 11(23)
Recent advances in microfluidics have created new and exciting prospects for gene delivery and therapy. The micro-scaled environment within microfluidic systems enables precise control and optimization of multiple processes and techniques used in gen