Výsledky vyhledávání - "Derek, Nichols"

Anti-4-1BB immunotherapy enhances systemic immune effects of radiotherapy to induce B and T cell-dependent anti-tumor immune activation and improve tumor control at unirradiated sites

Autor: Alexandra L. Martin, Chase Powell, Mate Z. Nagy, Patrick Innamarato, John Powers, Derek Nichols, Carmen M. Anadon, Ricardo A. Chaurio, Sungjune Kim, Min-hsuan Wang, Bing Gong, Xianzhe Wang, Thomas J. Scheutz, Scott J. Antonia, Jose R. Conejo-Garcia, Bradford A. Perez

Publikováno v: Cancer Immunology, Immunotherapy. 72:1445-1460

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4fa05464af5cd42df1696ea32ef09aa0
https://doi.org/10.1007/s00262-022-03325-y

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Anti-4-1BB immunotherapy enhances systemic immune effects of radiotherapy to induce B and T cell-dependent anti-tumor immune activation and improve tumor control at unirradiated sites

Autor: Alexandra L, Martin, Chase, Powell, Mate Z, Nagy, Patrick, Innamarato, John, Powers, Derek, Nichols, Carmen M, Anadon, Ricardo A, Chaurio, Sungjune, Kim, Min-Hsuan, Wang, Bing, Gong, Xianzhe, Wang, Thomas J, Scheutz, Scott J, Antonia, Jose R, Conejo-Garcia, Bradford A, Perez

Publikováno v: Cancer immunology, immunotherapy : CII.

Radiation therapy (RT) can prime and boost systemic anti-tumor effects via STING activation, resulting in enhanced tumor antigen presentation and antigen recognition by T cells. It is increasingly recognized that optimal anti-tumor immune responses b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5eaeae82a47c37bee4a5b2cc5405de64
https://pubmed.ncbi.nlm.nih.gov/36469096

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Evaluation of combined anti-PD-1 immunotherapy and radiation therapy in a preclinical mouse model of pneumonitis and fibrosis

Autor: David Noyes, Isabel L. Jackson, Theresa A. Boyle, Zeljko Vujaskovic, Kujtim Latifi, Scott J. Antonia, Bradford A. Perez, Derek Nichols, Vladimir Feygelman

Publikováno v: Journal of Thoracic Disease. 10:6254-6260

Outcomes for patients with inoperable locally advanced non-small cell lung cancer (LA-NSCLC) are poor, with a median survival of about 2 years (1) and a 5-year survival of about 10–15% following diagnosis, even among patients with good performance

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42eb0e81796f3ce46a269b9b46a4149b
https://doi.org/10.21037/jtd.2018.10.01

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