Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Dereje, Jima"'
Autor:
John G. Witherspoon, Jonathan R. Hall, Dereje Jima, Hannah M. Atkins, Nathan T. Wamsley, Michael B. Major, Bernard E. Weissman, Robert C. Smart
Publikováno v:
Redox Biology, Vol 75, Iss , Pp 103261- (2024)
Squamous cell carcinomas (SCCs), including lung, head & neck, bladder, and skin SCCs often display constitutive activation of the KEAP1-NRF2 pathway. Constitutive activation is achieved through multiple mechanisms, including activating mutations in N
Externí odkaz:
https://doaj.org/article/b4b5ffcf237641c591cfcf27bb61b4f8
Autor:
Cynthia A. Moylan, Alisha M. Mavis, Dereje Jima, Rachel Maguire, Mustafa Bashir, Jeongeun Hyun, Melanie N. Cabezas, Alice Parish, Donna Niedzwiecki, Anna Mae Diehl, Susan K. Murphy, Manal F. Abdelmalek, Cathrine Hoyo
Publikováno v:
Epigenetics, Vol 17, Iss 11, Pp 1446-1461 (2022)
Non-Alcoholic fatty liver disease (NAFLD) is the leading cause of chronic liver disease in children. Epigenetic alterations, such as through DNA methylation (DNAm), may link adverse childhood exposures and fatty liver and provide non-invasive methods
Externí odkaz:
https://doaj.org/article/340dddde15ac419da0f5f9f960cb993c
Autor:
Ayalew Ligaba-Osena, Mohammad Salehin, Muhammad Numan, Xuegeng Wang, Sang-Chul Choi, Dereje Jima, Louis-Marie Bobay, Wanli Guo
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract Calcium (Ca2+) is one of the essential mineral nutrients for plant growth and development. However, the effects of long-term Ca2+ deficiency in orphan crops such as Tef [(Eragrostis tef) (Zucc.) Trotter], which accumulate high levels of Ca i
Externí odkaz:
https://doaj.org/article/6d59aa3c258f49369c5be52df4645827
Autor:
Yi-Hui Zhou, Paul J. Gallins, Amy S. Etheridge, Dereje Jima, Elizabeth Scholl, Fred A. Wright, Federico Innocenti
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract In this study, we generated whole-transcriptome RNA-Seq from n = 192 genotyped liver samples and used these data with existing data from the GTEx Project (RNA-Seq) and previous liver eQTL (microarray) studies to create an enhanced transcript
Externí odkaz:
https://doaj.org/article/dfbeb7486ce4448bb00b807a6007bd53
Autor:
Claire Bosire, Adriana C. Vidal, Jennifer S. Smith, Dereje Jima, Zhiqing Huang, David Skaar, Fidel Valea, Rex Bentley, Margaret Gradison, Kimberly S. H. Yarnall, Anne Ford, Francine Overcash, Susan K. Murphy, Cathrine Hoyo
Publikováno v:
Infectious Agents and Cancer, Vol 16, Iss 1, Pp 1-8 (2021)
Abstract Background Epigenetic mechanisms are hypothesized to contribute substantially to the progression of cervical intraepithelial neoplasia (CIN) to cervical cancer, although empirical data are limited. Methods Women (n = 419) were enrolled at co
Externí odkaz:
https://doaj.org/article/d085b59df448466bb26395e2e4627db3
Autor:
Farideh Shafiee-Kermani, Skyla T. Carney, Dereje Jima, Utibe C. Utin, LaNeisha B. Farrar, Melvin O. Oputa, Marcono R. Hines, H. Karimi Kinyamu, Kevin W. Trotter, Trevor K. Archer, Cathrine Hoyo, Beverly H. Koller, Stephen J. Freedland, Delores J. Grant
Publikováno v:
Epigenetics, Vol 16, Iss 3, Pp 289-299 (2021)
Studies have suggested that abrogated expression of detoxification enzymes, UGT2B15 and UGT2B17, are associated with prostate tumour risk and progression. We investigated the role of EGF on the expression of these enzymes since it interacts with sign
Externí odkaz:
https://doaj.org/article/b07d19108d254966ae0dcb681885e3bb
Autor:
Chantel L. Martin, Dereje Jima, Gemma C. Sharp, Lauren E. McCullough, Sarah S. Park, Kymberly M. Gowdy, David Skaar, Michael Cowley, Rachel L. Maguire, Bernard Fuemmeler, David Collier, Caroline L. Relton, Susan K. Murphy, Cathrine Hoyo
Publikováno v:
Epigenetics, Vol 14, Iss 4, Pp 325-340 (2019)
Pre-pregnancy obesity is an established risk factor for adverse sex-specific cardiometabolic health in offspring. Epigenetic alterations, such as in DNA methylation (DNAm), are a hypothesized link; however, sex-specific epigenomic targets remain uncl
Externí odkaz:
https://doaj.org/article/12564e8e715f48988cbb8d8ce7df9bc6
Autor:
Timothy M. Frayling, Robin N. Beaumont, Samuel E. Jones, Hanieh Yaghootkar, Marcus A. Tuke, Katherine S. Ruth, Francesco Casanova, Ben West, Jonathan Locke, Seth Sharp, Yingjie Ji, William Thompson, Jamie Harrison, Amy S. Etheridge, Paul J. Gallins, Dereje Jima, Fred Wright, Yihui Zhou, Federico Innocenti, Cecilia M. Lindgren, Niels Grarup, Anna Murray, Rachel M. Freathy, Michael N. Weedon, Jessica Tyrrell, Andrew R. Wood
Publikováno v:
Cell Reports, Vol 23, Iss 2, Pp 327-336 (2018)
Summary: Fibroblast growth factor 21 (FGF21) is a hormone that has insulin-sensitizing properties. Some trials of FGF21 analogs show weight loss and lipid-lowering effects. Recent studies have shown that a common allele in the FGF21 gene alters the b
Externí odkaz:
https://doaj.org/article/8e545f5ef1c049678531993af30ecc37
Publikováno v:
BMC Bioinformatics, Vol 19, Iss 1, Pp 1-11 (2018)
Abstract Background Expression quantitative trait loci (eQTL) analysis identifies genetic markers associated with the expression of a gene. Most existing eQTL analyses and methods investigate association in a single, readily available tissue, such as
Externí odkaz:
https://doaj.org/article/b09f90eb74cf4bf89d2b0e597680b5df
Autor:
Kylie D Rock, Brian Horman, Allison L Phillips, Susan L McRitchie, Scott Watson, Jocelin Deese-Spruill, Dereje Jima, Susan Sumner, Heather M Stapleton, Heather B Patisaul
Publikováno v:
Endocrine Connections, Vol 7, Iss 2, Pp 305-324 (2018)
Firemaster 550 (FM 550) is a flame retardant (FR) mixture that has become one of the most commonly used FRs in foam-based furniture and baby products. Human exposure to this commercial mixture, composed of brominated and organophosphate components, i
Externí odkaz:
https://doaj.org/article/413517ca812841eea6a4358d0d174120