Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Deranda B, Lester"'
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Sensory stimuli are natural rewards in mice and humans. Consequently, preference for a drug reward relative to a sensory reward may be an endophenotype of addiction vulnerability. In this study, we developed a novel behavioral assay to quant
Externí odkaz:
https://doaj.org/article/67b88ce15481454e8726a339e01c0dfa
Publikováno v:
Brain Sciences, Vol 14, Iss 1, p 20 (2023)
Over the past 80 years, research on dopamine has undergone significant evolution, reshaping our understanding of its roles in the brain and the body [...]
Externí odkaz:
https://doaj.org/article/de8cb3ced9f14688aea75bfb2341a985
Publikováno v:
Experimental Brain Research. 240:2803-2815
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d39d3514d54ca8135e4fea8597fccbb
https://doi.org/10.1007/s00221-022-06449-w
https://doi.org/10.1007/s00221-022-06449-w
Autor:
Michael T. Williams, Alyssa D Johnson, Lauren M Estes, Deranda B. Lester, Samantha L Regan, Destinee M Cruthird, Joshua L Potter, Hunter G Nolen, Charles V. Vorhees, Helen J.K. Sable
Publikováno v:
Genes, brain, and behaviorREFERENCES. 20(8)
Attention-deficit/hyperactivity disorder (ADHD) a common neurodevelopmental disorder of childhood and often comorbid with other externalizing disorders (EDs). There is evidence that externalizing behaviors share a common genetic etiology. Recently, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff39446b22b2f4aa8d01ed5dea3be63d
https://pubmed.ncbi.nlm.nih.gov/34427038
https://pubmed.ncbi.nlm.nih.gov/34427038
Publikováno v:
Neuropsychopharmacology
The risky decision-making task (RDT) measures risk-taking in a rat model by assessing preference between a small, safe reward and a large reward with increasing risk of punishment (mild foot shock). It is well-established that dopaminergic drugs modu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f54d05294d07673d8bb5b4d77ff48bfa
https://doi.org/10.1038/s41386-019-0527-0
https://doi.org/10.1038/s41386-019-0527-0
Autor:
Nick B. Paige, Josiah F. Comstock, Deranda B. Lester, Zade Holloway, Helen J.K. Sable, Hunter G Nolen
Publikováno v:
The Cerebellum. 18:922-931
Cerebral and cerebellar hemispheres are known to be asymmetrical in structure and function, and previous literature supports that asymmetry extends to the neural dopamine systems. Using in vivo fixed-potential amperometry with carbon-fiber microelect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::137452b520ddba2dd950e8521447b1d7
https://doi.org/10.1007/s12311-019-01074-w
https://doi.org/10.1007/s12311-019-01074-w
Autor:
Deranda B. Lester, Megan A McWain, Hunter G Nolen, Kevin M Honeywell, Helen J.K. Sable, Timothy G. Freels, Abigail S Chaffin
A major problem with current anxiolytic medications is abuse liability; thus, new pharmaceutical targets are being explored. The cannabinoid system is one potential target. The current paper examined behavioral and neurochemical changes related to ab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a544d4d7a9f4418fd9c0c57c9a7f48da
https://doi.org/10.1101/2020.06.14.150755
https://doi.org/10.1101/2020.06.14.150755
Autor:
Melissa J. Puppa, Mary K. Estes, Jasric J. Bland, Douglas W. Powell, Deranda B. Lester, Kenya K. Ector
Publikováno v:
Neuroscience Letters. 756:135952
Natural rewards, such as food and social interaction, as well as drugs of abuse elicit increased mesolimbic dopamine release in the nucleus accumbens (NAc). Drugs of abuse, however, increase NAc dopamine release to a greater extent and are known to i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec32020d072f34237ffb90795814e4a0
https://doi.org/10.1016/j.neulet.2021.135952
https://doi.org/10.1016/j.neulet.2021.135952
Publikováno v:
Neuroscience. 408
Growing research indicates oxytocin may be involved in relieving anxiety and attenuating the rewarding effects of psychostimulants. This study investigated the effects of subchronic oxytocin treatments on mesolimbic dopamine transmission in areas ass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::344bd05ce0ac17d1e80725a8bc28c94f
https://pubmed.ncbi.nlm.nih.gov/30981861
https://pubmed.ncbi.nlm.nih.gov/30981861
Publikováno v:
Behavioural brain research. 362
Cannabinergic and vanilloidergic signaling are potential mechanisms for the treatment of anxiety symptoms because of the anxiolytic properties of cannabinoid type 1 receptor (CB1R) activation and transient potential vanilloid type 1 channel (TRPV1) i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7f4f3a8529c1179588fff9725ce62bd
https://pubmed.ncbi.nlm.nih.gov/30639609
https://pubmed.ncbi.nlm.nih.gov/30639609