Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Deqin Lu"'
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
IntroductionMyocardial ischemia-reperfusion injury (MIRI) is a prevalent complication in patients with myocardial infarction. The pathological mechanism of MIRI remains elusive. Ferroptosis plays a critical role in MIRI. This study aimed to investiga
Externí odkaz:
https://doaj.org/article/ecedf342232943a68d626bbc44c02601
Autor:
Ming Ni, Jing Cui, Xin Yang, Yuntian Ding, Peng Zhao, Tianzhen Hu, Yun Zhan, Qian Kang, Xiuying Hu, Jiangyuan Zhao, Yao Xu, Lu Chen, Min Liu, Mei Zhao, Fengqi Zhang, Shisi Huang, Ya Li, Xueying Yang, Luxin Zhang, Tianzhuo Zhang, Bo Deng, Bing Yang, Deqin Lu, Jishi Wang
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionGranulocytic myeloid-derived suppressor cells (G-MDSCs) show fast recovery following allogeneic hematopoietic stem cell transplantation (allo-HSCT) constituting the major part of peripheral blood in the early phase. Although G-MDSCs media
Externí odkaz:
https://doaj.org/article/2d56aec18a4a41d7828192e38723290a
Autor:
Xin Chai, Zhengwei Liang, Junshi Zhang, Jing Ding, Qian Zhang, Sha Lv, Yazhu Deng, Rongrui Zhang, Deqin Lu
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Increasing evidences demonstrate that chlorogenic acid (CGA), a polyphenol with multiple effects such as anti-inflammatory and anti-oxidation, protects against myocardial ischemia–reperfusion injury (MIRI) in vitro and in vivo. But its det
Externí odkaz:
https://doaj.org/article/353f2c9889694b3ead7969dd95bffa5c
Autor:
Jing Ding, Min Yu, Juncai Jiang, Yanbei Luo, Qian Zhang, Shengnan Wang, Fei Yang, Alei Wang, Lingxiao Wang, Mei Zhuang, Shan Wu, Qifang Zhang, Yong Xia, Deqin Lu
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Increasing evidences suggest that angiotensin (Ang) II participates in the pathogenesis of endothelial dysfunction (ED) through multiple signaling pathways, including angiotensin type 1 receptor (AT1R) mediated NADPH oxidase (Nox)/reactive oxygen spe
Externí odkaz:
https://doaj.org/article/d850ebab98074c969807b3972cc481bf
NP-1 Reverses Left Ventricular Remodeling in Hypertension through Inhibiting NF-KB Signaling Pathway
Autor:
Xiaorong duan, Zhenqiu Yu, Xiaoyun Si, Deqin Lu, Dan Liu, Dianqin XU, Pinwei Zhou, Xue Zhao, meng meng, Qinhui He
BACKGROUND Reversing hypertensive ventricular remodeling could reduce cardiovascular disease, but it’s reversal rate is low. Neutrophil Peptide 1 ( NP-1 ) is under intensive investigation as a potential therapeutic agent. But it’s role in hyperte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aafe51d4a43d9d18aa6401b0b5d0e993
https://doi.org/10.21203/rs.3.rs-2291750/v1
https://doi.org/10.21203/rs.3.rs-2291750/v1
Autor:
Qian Zhang, Alei Wang, Juncai Jiang, Fei Yang, Yanbei Luo, Deqin Lu, Shengnan Wang, Jing Ding, Lingxiao Wang, Yong Xia, Min Yu, Shan Wu
Publikováno v:
Biochemical and Biophysical Research Communications. 516:613-618
The chronic elevation of angiotensin II (Ang II) is an important cause of endothelial dysfunction (ED). The Ang II/type 1 receptor (AT1R) signaling pathway can cause endothelial nitric oxide synthase (eNOS)/nitric oxide (NO) dysfunction through vario
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::39c6301a864f2c55e9aae21ef04800de
https://doi.org/10.1016/j.bbrc.2019.06.063
https://doi.org/10.1016/j.bbrc.2019.06.063
Publikováno v:
Cellular Signalling. 58:44-52
Persistent inflammasome activation contributes to chronic, low grade inflammation. However, it is unclear how the inflammasome activation is sustained after initiation. Here we reported that N4-acetylcytidine (N4A), a nucleoside metabolite, activated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d4df106a8430360877e02ab7af91a400
https://doi.org/10.1016/j.cellsig.2019.03.007
https://doi.org/10.1016/j.cellsig.2019.03.007
Publikováno v:
Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology. 36(6)
Objective To investigate the roles of protein phosphatase 2C (PP2C) activated by palmitic acid (PA) in the phosphorylation modulation of endothelial nitric oxide (eNOS) at the site of serine 1177 (eNOS Ser1177) in human umbilical vein endothelial cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9a33b086f78e3b18be9745e1a53a780c
https://pubmed.ncbi.nlm.nih.gov/32696742
https://pubmed.ncbi.nlm.nih.gov/32696742
Autor:
Yuhui Peng, Qifang Zhang, Jian Zhang, Tenxiang Chen, Wen-Feng Yu, Yan Xiao, Yan He, Hua Bai, Qinrong Wang, Yan Zhao, Jianjiang Zhou, Yuan Xie, Penxiang Guo, Changxue Wu, Deqin Lu, Tin Zhang
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1868:166268
Objective Treatment of acute myeloid leukemia (AML) remains a challenge. It is urgent to understand the microenvironment to improve therapy and prognosis. Methods Bioinformatics methods were used to analyze transcription expression profile of AML pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e406a0bd424ada431324594d8fb182c
https://doi.org/10.1016/j.bbadis.2021.166268
https://doi.org/10.1016/j.bbadis.2021.166268
Autor:
Yanbei, Luo, Qian, Zhang, Jing, Ding, Min, Yu, Juncai, Jiang, Fei, Yang, Shengnan, Wang, Alei, Wang, Lingxiao, Wang, Shan, Wu, Yong, Xia, Deqin, Lu
Publikováno v:
Biochemical and biophysical research communications. 516(3)
The chronic elevation of angiotensin II (Ang II) is an important cause of endothelial dysfunction (ED). The Ang II/type 1 receptor (AT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b59aa50a6a337c18ed9ebee9b8ba8ee0
https://pubmed.ncbi.nlm.nih.gov/31239152
https://pubmed.ncbi.nlm.nih.gov/31239152