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Akademický článek

What predicts the clinical benefits of PARP inhibitors in platinum-sensitive recurrent ovarian cancer: A real-world single-center retrospective cohort study from China

Autor: Depu Zhang, Shuo Li, Xinxin Zhang, Jingwei Peng, Shiqian Zhang

Publikováno v: Frontiers in Oncology, Vol 12 (2022)

ObjectiveThis study assessed the real-world application, effectiveness, and safety of olaparib and niraparib as maintenance therapies in patients with platinum-sensitive recurrent ovarian cancer (PSROC) in China and investigated clinical factors asso

Externí odkaz: https://doaj.org/article/f8f917ad008d46d599880c6c21cc1aaa

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Akademický článek

The impact of matrix metalloproteinase 2 on prognosis and clinicopathology of breast cancer patients: a systematic meta-analysis.

Autor: Yiping Chen, Xiaochen Wang, Guodi Chen, Caixia Dong, Depu Zhang

Publikováno v: PLoS ONE, Vol 10, Iss 3, p e0121404 (2015)

Matrix metalloproteinase 2 (MMP-2) plays a crucial role in the progression of breast cancer (BC). The prognostic role of MMP-2 expression in BC patients has been widely reported, but the results were inconsistent. Thus, a meta-analysis was conducted

Externí odkaz: https://doaj.org/article/a98813776e844a999dcd4356daa0d0ed

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Molecular insight into the π‐stacking interactions of human ovarian cancer PARP‐1 with its small‐molecule inhibitors and rational design of aromatic amino acid‐rich peptides to target PARP‐1 based on the π‐stacking network

Autor: Chunxia Pan, Lei Chen, Xinxin Zhang, Depu Zhang, Quqing Song, Jingwei Peng, Qingshui Li

Publikováno v: Journal of the Chinese Chemical Society. 69:775-785

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2939eb3b5b8111588bba115140e31011
https://doi.org/10.1002/jccs.202200004

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EP304/#313 Efficacy and safety of niraparib combined with oral etoposide in platinum resistant/refractory recurrent ovarian cancer: a multicentre, single arm, prospective phase II trial

Autor: Huimei Zhou, Jiaxin Yang, Qian Liu, Qingshui Li, Depu Zhang, Dongyan Cao, Yang Xiang

Publikováno v: E-Posters.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1012155320ff4a955dad924d1e016b4a
https://doi.org/10.1136/ijgc-2022-igcs.394

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Efficacy and safety of niraparib combined with oral etoposide in platinum-resistant/refractory ovarian cancer (PROC): a single arm, phase 2 study

Autor: Jiaxin Yang, Huimei Zhou, Qingshui Li, Depu Zhang, Dongyan Cao, Yang Xiang

Publikováno v: Proceedings of the 7th Biennial Meeting of Asian Society of Gynecologic Oncology.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ac9a476486956600aebf03355799d7e1
https://doi.org/10.3802/jgo.2021.32.s1.oo1

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GABAergic signaling facilitates breast cancer metastasis by promoting ERK1/2-dependent phosphorylation

Autor: Chuanfei Wei, Ziming Yao, Xiaowei Li, Jingxin Li, Nannan Ning, Depu Zhang

Publikováno v: Cancer Letters. 348:100-108

The present study aims to determine the role of γ-aminobutyric acid (GABA) signaling molecules in breast cancer metastasis. Our results reveal that GABAergic system exists in breast cancer cells. Both the GABA synthetic enzyme. (GAD65/67) and GABAB

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::057ea4a138b7828106a31b25da89af70
https://doi.org/10.1016/j.canlet.2014.03.006

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The prognostic implication of slug in all tumour patients - a systematic meta-analysis

Autor: Xisheng Weng, Ping Zhang, Cheng Huang, Depu Zhang

Publikováno v: European journal of clinical investigation. 46(5)

BACKGROUND E-cadherin is an invasion suppressor molecule which counteracts tumour metastasis and progression. Slug, one of the crucial transcriptional repressors of E-cadherin gene, has been widely reported on its prognostic role in patients with car

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a10ac2dbd6edc69b4c3add70b7714d59
https://pubmed.ncbi.nlm.nih.gov/26919035

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The Impact of Matrix Metalloproteinase 2 on Prognosis and Clinicopathology of Breast Cancer Patients: A Systematic Meta-Analysis

Autor: Guodi Chen, Xiaochen Wang, Yiping Chen, Caixia Dong, Depu Zhang

Publikováno v: PLoS ONE, Vol 10, Iss 3, p e0121404 (2015)
PLoS ONE

Backgrounds Matrix metalloproteinase 2 (MMP-2) plays a crucial role in the progression of breast cancer (BC). The prognostic role of MMP-2 expression in BC patients has been widely reported, but the results were inconsistent. Thus, a meta-analysis wa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::281f66151b9fe7476fd46421b85de9da
https://doi.org/10.1371/journal.pone.0121404

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