Zobrazeno 1 - 10
of 178
pro vyhledávání: '"Dep Biochemie en Celbiologie"'
Autor:
Costermans, N G J, Teerds, K J, Middelkoop, A, Roelen, B A J, Schoevers, E J, van Tol, H T A, Laurenssen, B, Koopmanschap, R E, Zhao, Y, Blokland, M, van Tricht, F, Zak, L, Keijer, J, Kemp, B, Soede, N M, Dep Biochemie en Celbiologie, Sub Software Technology begr. 1-1-13, LS Voortplanting Inwendige Ziekten, Sub Celbiologisch lab., dES/dFAH FR, Dep Gezondheidszorg Landbouwhuisdieren, Sub Condensed Matter and Interfaces
Publikováno v:
Biology of Reproduction. Society for the Study of Reproduction
Biology of Reproduction, 102(2), 388-398
Biology of Reproduction
Biology of Reproduction 102 (2020) 2
Biology of Reproduction, 102(2), 388-398
Biology of Reproduction
Biology of Reproduction 102 (2020) 2
Metabolic demands of modern hybrid sows have increased over the years, which increases the chance that sows enter a substantial negative energy balance (NEB) during lactation. This NEB can influence the development of follicles and oocytes that will
Autor:
Bexkens, Michiel L, Mebius, Mirjam M, Houweling, Martin, Brouwers, Jos F, Tielens, Aloysius G M, van Hellemond, Jaap J, Afd Chemical Biology and Drug Discovery, dB&C FR-RMSC RMSC, LS Veterinaire biochemie, Sub MS-faciliteit, LS Biochemie van parasieten, Dep Biochemie en Celbiologie
Publikováno v:
International Journal for Parasitology, 49(8), 647. Elsevier Limited
International Journal for Parasitology, 49(8), 647-656. Elsevier Ltd.
International Journal for Parasitology, 49(8), 647-656. Elsevier Ltd.
Adult schistosomes, parasitic flatworms that cause the tropical disease schistosomiasis, have always been considered to be homolactic fermenters and in their energy metabolism strictly dependent on carbohydrates. However, more recent studies suggeste
Autor:
Sheng, Jie, Olrichs, Nick K., Geerts, Willie J., Kaloyanova, Dora V., Helms, J. Bernd, LS Veterinaire biochemie, dB&C FR-RMSC FR, Sub Cryo - EM, Dep Biochemie en Celbiologie, dB&C FR-RMSC RMSC
Publikováno v:
Scientific Reports, 9(1). NLM (Medline)
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
Scientific Reports
Members of the CAP superfamily (Cysteine-rich secretory proteins, Antigen 5, and Pathogenesis-Related 1 proteins) are characterized by the presence of a structurally conserved CAP domain. The common structure-function relationship of this domain is s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aea1fa344c0fd688ca3183b7316b584a
https://dspace.library.uu.nl/handle/1874/391522
https://dspace.library.uu.nl/handle/1874/391522
Autor:
Sarink, M. J., Koelewijn, R., Slingerland, B. C.G.C., Tielens, A. G.M., van Genderen, P. J.J., van Hellemond, J. J., LS Veterinaire biochemie, Dep Biochemie en Celbiologie
Publikováno v:
Journal of Helminthology, 93(5), 636-639. Cambridge University Press
Journal of Helminthology, 93(5), 636. Cambridge University Press
Journal of Helminthology, 93(5), 636. Cambridge University Press
Diagnosis of cystic echinococcosis (CE) is at present mainly based on imaging techniques. Serology has a complementary role, partly due to the small number of standardized and commercially available assays. Therefore we examined the clinical performa
Autor:
Clark, Chantal C., Mebius, Mirjam M., de Maat, Steven, Tielens, Aloysius G.M., de Groot, Philip G, Urbanus, Rolf T, Fijnheer, Rob, Hazenberg, Bouke P.C., Van Hellemond, Jaap J., Maas, Coen, Afd Chemical Biology and Drug Discovery, LS Veterinaire biochemie, Dep Biochemie en Celbiologie
Publikováno v:
Thrombosis and Haemostasis, 118(3), 471-479. Georg Thieme Verlag
Thrombosis and Haemostasis, 118(3), 471-479. GEORG THIEME VERLAG KG
Thrombosis and Haemostasis, 118(3), 471. Schattauer GmbH
Thrombosis and Haemostasis, 118(3), 471-479. GEORG THIEME VERLAG KG
Thrombosis and Haemostasis, 118(3), 471. Schattauer GmbH
ADAMTS13 (a disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13) cleaves von Willebrand Factor (VWF) multimers to control their thrombogenicity. The fibrinolytic enzyme plasmin can cleave VWF in a similar manner. However,
Autor:
Kruitwagen, Hedwig S., Oosterhoff, Loes A., Vernooij, Ingrid G W H, Schrall, Ingrid M., van Wolferen, Monique E., Bannink, Farah, Roesch, Camille, van Uden, Lisa, Molenaar, Martijn R., Helms, J. Bernd, Grinwis, Guy C.M., Verstegen, Monique M A, van der Laan, Luc J W, Huch, Meritxell, Geijsen, Niels, Vries, Robert R G, Clevers, Hans, Rothuizen, Jan, Schotanus, Baukje A., Penning, Louis C., Spee, Bart, dB&C FR-RMSC FR, dCSCA RMSC-1, dPB CR, dCSCA AVR, Onderzoek, Biochemisch laboratorium, LS Pathologie, Sub Biochemie Algemeen, Dep Biochemie en Celbiologie, LS Veterinaire biochemie, Veterinair Pathologisch Diagnostisch Cnt, PB AVM, Applied Veterinary Research, Dep Pathobiologie, Faculteit Diergeneeskunde, LS Interne geneeskunde
Publikováno v:
Stem Cell Reports, Vol 8, Iss 4, Pp 822-830 (2017)
Stem Cell Reports, 8(4), 822-830. Cell Press
Stem Cell Reports, 8(4), 822. Cell Press
Stem Cell Reports
Stem Cell Reports [E], 8(4), 822. Cell Press
Stem Cell Reports, 8(4), 822-830. Cell Press
Stem Cell Reports, 8(4), 822. Cell Press
Stem Cell Reports
Stem Cell Reports [E], 8(4), 822. Cell Press
Summary Hepatic steatosis is a highly prevalent liver disease, yet research is hampered by the lack of tractable cellular and animal models. Steatosis also occurs in cats, where it can cause severe hepatic failure. Previous studies demonstrate the po
Autor:
Ajat, Mokrish, Molenaar, Martijn, Brouwers, Jos F H M, Vaandrager, Arie B., Houweling, Martin, Helms, J. Bernd, Sub Biochemie Algemeen, LS Veterinaire biochemie, Sub MS-faciliteit, Dep Biochemie en Celbiologie, dB&C FR-RMSC FR
Publikováno v:
Biochimica et Biophysica Acta-Molecular and Cell Biology of Lipids, 1862(2), 176. Elsevier
Hepatic stellate cells (HSCs) play an important role in liver physiology and under healthy conditions they have a quiescent and lipid-storing phenotype. Upon liver injury, HSCs are activated and rapidly lose their retinyl ester-containing lipid dropl
Autor:
Milne, Kirsty, Sun, Jianhui, Zaal, Esther A., Mowat, Jenna, Celie, Patrick H.N., Fish, Alexander, Berkers, Celia R., Forlani, Giuseppe, Loayza-Puch, Fabricio, Jamieson, Craig, Agami, Reuven, Sub Biomol.Mass Spectrometry & Proteom., LS Veterinaire biochemie, dB&C FR-RMSC RMSC, Biomolecular Mass Spectrometry and Proteomics, Dep Biochemie en Celbiologie
Publikováno v:
Bioorganic and Medicinal Chemistry Letters, 29(18), 2626. Elsevier
Bioorganic & Medicinal Chemistry Letters, 29(18), 2626-2631. Elsevier Ltd.
Bioorganic & Medicinal Chemistry Letters, 29(18), 2626-2631. Elsevier Ltd.
Pyrroline-5-carboxylate reductase 1 (PYCR1) is the final enzyme involved in the biosynthesis of proline and has been found to be upregulated in various forms of cancer. Due to the role of proline in maintaining the redox balance of cells and preventi
Autor:
van der Kant, Rik, Langness, Vanessa F, Herrera, Cheryl M, Williams, Daniel A, Fong, Lauren K, Leestemaker, Yves, Steenvoorden, Evelyne, Rynearson, Kevin D, Brouwers, Jos F, Helms, J Bernd, Ovaa, Huib, Giera, Martin, Wagner, Steven L, Bang, Anne G, Goldstein, Lawrence S B, Sub Cell Biology, dB&C FR-RMSC FR, dB&C FR-RMSC RMSC, LS Veterinaire biochemie, Sub MS-faciliteit, Dep Biochemie en Celbiologie
Publikováno v:
Cell Stem Cell, 24(3), 363
van der Kant, R, Langness, V F, Herrera, C M, Williams, D A, Fong, L K, Leestemaker, Y, Steenvoorden, E, Rynearson, K D, Brouwers, J F, Helms, J B, Ovaa, H, Giera, M, Wagner, S L, Bang, A G & Goldstein, L S B 2019, ' Cholesterol Metabolism Is a Druggable Axis that Independently Regulates Tau and Amyloid-β in iPSC-Derived Alzheimer's Disease Neurons ', Cell Stem Cell, vol. 24, no. 3, pp. 363-375.e9 . https://doi.org/10.1016/j.stem.2018.12.013
Cell Stem Cell, 24(3), 363-375.e9. Elsevier
Cell Stem Cell, 24(3). Cell Press
van der Kant, R, Langness, V F, Herrera, C M, Williams, D A, Fong, L K, Leestemaker, Y, Steenvoorden, E, Rynearson, K D, Brouwers, J F, Helms, J B, Ovaa, H, Giera, M, Wagner, S L, Bang, A G & Goldstein, L S B 2019, ' Cholesterol Metabolism Is a Druggable Axis that Independently Regulates Tau and Amyloid-β in iPSC-Derived Alzheimer's Disease Neurons ', Cell Stem Cell, vol. 24, no. 3, pp. 363-375.e9 . https://doi.org/10.1016/j.stem.2018.12.013
Cell Stem Cell, 24(3), 363-375.e9. Elsevier
Cell Stem Cell, 24(3). Cell Press
Genetic, epidemiologic, and biochemical evidence suggests that predisposition to Alzheimer's disease (AD) may arise from altered cholesterol metabolism, although the molecular pathways that may link cholesterol to AD phenotypes are only partially und
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::028a2b3c551e4c9f3ddb653aa5df1bbd
http://hdl.handle.net/1887/120398
http://hdl.handle.net/1887/120398
Autor:
Haaker, Maya W, Kruitwagen, Hedwig S, Vaandrager, Arie B, Houweling, Martin, Penning, Louis C, Molenaar, Martijn R, van Wolferen, Monique E, Oosterhoff, Loes A, Spee, Bart, Helms, J Bernd, LS Veterinaire biochemie, dB&C FR-RMSC RMSC, LS Interne geneeskunde, dCSCA RMSC-1, Onderzoek, dCSCA AVR, Sub Biochemie Algemeen, Biochemisch laboratorium, Dep Biochemie en Celbiologie, dB&C FR-RMSC FR, CS_STEM
Publikováno v:
Journal of Veterinary Internal Medicine
Journal of Veterinary Internal Medicine, Vol 34, Iss 1, Pp 132-138 (2020)
Journal of Veterinary Internal Medicine, 34(1), 132. Wiley-Blackwell
Journal of Veterinary Internal Medicine, Vol 34, Iss 1, Pp 132-138 (2020)
Journal of Veterinary Internal Medicine, 34(1), 132. Wiley-Blackwell
Background Hepatic lipidosis is increasing in incidence in the Western world, with cats being particularly sensitive. When cats stop eating and start utilizing their fat reserves, free fatty acids (FFAs) increase in blood, causing an accumulation of