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of 2 320
pro vyhledávání: '"Deoxyribonucleoside"'
Akademický článek
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Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 1996 Oct . 93(22), 12519-12524.
Externí odkaz:
https://www.jstor.org/stable/40650
Autor:
Mahak Fatima, Muhammad Mubashar Iqbal Ahmed, Faiza Batool, Anjum Riaz, Moazzam Ali, Birgitte Munch-Petersen, Zeeshan Mutahir
Publikováno v:
Biomolecules & Biomedicine, Vol 19, Iss 4 (2019)
A recombinant deoxyribonucleoside kinase from Drosophila melanogaster with a deletion of the last 20 amino acid residues (named DmdNKΔC20) was hypothesized as a potential therapeutic tool for gene therapy due to its broad substrate specificity and b
Externí odkaz:
https://doaj.org/article/09082df056ca48088f55a8618e19c124
Publikováno v:
Frontiers in Genetics, Vol 9 (2018)
Mitochondrial neurogastrointestinal encephalomyopathy (MNGIE) is an ultra-rare metabolic autosomal recessive disease, caused by mutations in the nuclear gene TYMP which encodes the enzyme thymidine phosphorylase. The resulting enzyme deficiency leads
Externí odkaz:
https://doaj.org/article/c4bf83045c854b4e8d6dec00184aa009
Akademický článek
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Akademický článek
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Publikováno v:
Viruses; Volume 15; Issue 1; Pages: 31
Reverse transcriptase (RT) and integrase (IN) are encoded tandemly in the pol genes of retroviruses. We reported recently that HIV-1 RT and IN need to be supplied as the pol precursor intermediates, in which RT and IN are in fusion form (RTIN) to exe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a7e76034b4c7e18075b29d404c7aa2d
Autor:
Krakovka, Sascha, Ranjbarian, Farahnaz, Luján, Lucas A., Saura, Alicia, Larsen, Nicolai B., Jiménez-González, Alejandro, Reggenti, Anna, Luján, Hugo D., Svärd, Staffan G., Hofer, Anders
Publikováno v:
Krakovka, Sascha, Ranjbarian, Farahnaz, Luján, Lucas A. ORCID: https://orcid.org/0000-0003-4235-4301 , Saura, Alicia ORCID: https://orcid.org/0000-0003-1537-506X , Larsen, Nicolai B., Jiménez-González, Alejandro ORCID: https://orcid.org/0000-0003-3493-4154 , Reggenti, Anna, Luján, Hugo Daniel ORCID: https://orcid.org/0000-0002-3797-8315 , Svärd, Staffan G. and Hofer, Anders (2022) Giardia intestinalis thymidine kinase is a high-affinity enzyme crucial for DNA synthesis and an exploitable target for drug discovery. Journal of Biological Chemistry, 298 (6). ISSN 0021-9258
Giardiasis is a diarrheal disease caused by the unicellular parasite Giardia intestinalis, for which metronidazole is the main treatment option. The parasite is dependent on exogenous deoxyribonucleosides for DNA replication and thus is also potentia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::16edd4f9b2b2af24ee8a0b19f712b1ad
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-196718
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-196718
Autor:
Shuvankar Naskar, Jens Müller
Publikováno v:
Inorganic Chemistry. 60:14765-14771
Metal-mediated base pairs enable a site-specific incorporation of transition metal ions into nucleic acid structures. The resulting nucleic acid-metal complex conjugates are of interest in the context of functionalized nucleic acids, as they bear met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80b806e732200eb8a5c2d2889c0a11fc
https://doi.org/10.1021/acs.inorgchem.1c01971
https://doi.org/10.1021/acs.inorgchem.1c01971
Autor:
Ayako Furugen, Taiki Yamamura, Ken Iseki, Tsukika Ohata, Takao Mori, Hiroshi Satoh, Masaki Kobayashi, Katsuya Narumi
Publikováno v:
Biochemical and Biophysical Research Communications. 558:120-125
Human concentrative nucleoside transporters (CNTs) are responsible for cellular uptake of ribonucleosides; however, although it is important to better characterize CNT-subtype specificity to understand the systemic disposition of deoxyribonucleosides
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4cb868ceb87f89f3505d0d8f9ccba0d
https://doi.org/10.1016/j.bbrc.2021.04.075
https://doi.org/10.1016/j.bbrc.2021.04.075