Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Deoxyadenosine Derivatives"'
Autor:
D. G. I. Petra, R. F. de Boer, G. J. Koomen, N. J. Meeuwenoord, E. Kuyl-Yeheskiely, G. A. van der Marel, J. H. van Boom
Publikováno v:
Recueil des Travaux Chimiques des Pays-Bas. 115:99-102
Strong fluorescent deoxyadenosine derivatives are of considerable research importance in cell biology. We prepared the deoxyriboside of methyl 3,7-dihydro-7-oxo-[2,1-i]pyrimidopurine-9-carboxylate (compound 1b, deoxyribofuranosyl A*)1 which was subse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7414d875350218ed2ef3f34f0571bd34
https://doi.org/10.1002/recl.19961150117
https://doi.org/10.1002/recl.19961150117
Autor:
Shi Houguang, Matt A. Peterson, Brenda R. McDougall, Carl Jones, W. Edward Robinson, Pucheng Ke
Publikováno v:
Nucleosides, Nucleotides and Nucleic Acids. 26:499-519
3'-Carboxymethyl-3'-deoxyadenosine derivatives were prepared from 2'-O-TBDMS-3'-[(ethoxycarbonyl)methyl]-3'-deoxyadenosine (1) via simple and efficient procedures. Conversion of 1 to its 5'-azido-5'-deoxy derivative 5 was accomplished via a novel one
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff8abe266f19a9aaa538c67796bd90ed
https://doi.org/10.1080/15257770701426278
https://doi.org/10.1080/15257770701426278
Publikováno v:
Tetrahedron Letters. 46:7605-7608
Novel base-discriminating fluorescent (BDF) nucleoside, 8-fluorescence-labeled adenosine derivative ( 8Py A ), was developed for the detection of thymine base on a target DNA. The BDF nucleoside was incorporated into oligodeoxynucleotides by post-syn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6565e2318f36d59afda924c1b14a7952
https://doi.org/10.1016/j.tetlet.2005.08.157
https://doi.org/10.1016/j.tetlet.2005.08.157
Publikováno v:
Letters in Organic Chemistry. 1:179-182
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b66dc55049ff1eeb6959aabd01d0cab8
https://doi.org/10.2174/1570178043488419
https://doi.org/10.2174/1570178043488419
Publikováno v:
Organic Letters. 7:2477-2479
[reaction: see text] An efficient route to deoxyadenosine derivatives labeled on both the amino group and nitrogen 1 is uncovered. First, 3',5'-di-O-acetyl-2'-deoxy-1-(2-nitrobenzenesulfonyl)inosine (2a) and only 1.1 equiv of (15)NH4Cl are used for l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::410a42c40c5c1743c9788d72934578d6
https://doi.org/10.1021/ol050788w
https://doi.org/10.1021/ol050788w
Publikováno v:
Journal of Medicinal Chemistry. 37:3850-3854
Appropriately protected nucleoside 5'-O-(2-thio-1,3,2-dithiaphospholanes) react with inorganic pyrophosphate in the presence of a strong base catalyst (DBU) to give nucleoside 5'-O-(1,1-dithiotriphosphates) 1a-g. The latter compounds, including an AZ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07c85413c23c95abe4072beb6ecc7367
https://doi.org/10.1021/jm00048a021
https://doi.org/10.1021/jm00048a021
Publikováno v:
Organicbiomolecular chemistry. 7(4)
It was found that N-arylcarbamoyl and N-(phenylsulfonyl)carbamoyl (psc) groups could be effectively introduced onto the amino groups of deoxycytidine and deoxyadenosine derivatives and could be removed thermolytically. We succeeded in synthesizing DN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::796153db3d39e8f194854f2b3ed6f89a
https://pubmed.ncbi.nlm.nih.gov/19194584
https://pubmed.ncbi.nlm.nih.gov/19194584
Publikováno v:
Nucleosides, Nucleotides and Nucleic Acids. 14:409-411
A series of 3′-substituted 3′-amino-3′-deoxyadenosine analogues were synthesized and subsequently tested against the human malaria parasite Plasmodium falciparum in vitro. Several amongst them displayed pronounced antiplasmodial activities.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5ea78297a06e19c877fe39989447372
https://doi.org/10.1080/15257779508012396
https://doi.org/10.1080/15257779508012396
Autor:
Sauro Vittori, Rosaria Volpini, Catia Lambertucci, Alberto Vita, Gloria Cristalli, Daniela Salvatori, Sara Taffi, Silvia Vincenzetti, Stefano Costanzi
Publikováno v:
Nucleosides, nucleotidesnucleic acids. 22(5-8)
N6-Cycloalkyl-2',3'-dideoxyadenosine derivatives and (2-chloro)-N6-cycloheptyl-3-deazaadenosine have been synthesized and tested, along with other (deaza)purine (deoxy)nucleosides from our chemical library, as inhibitors of virus replication against
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df4f0a56ec637fc0db5b642abf1188d2
https://pubmed.ncbi.nlm.nih.gov/14565301
https://pubmed.ncbi.nlm.nih.gov/14565301
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