Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Deondra T. Brown"'
Autor:
Myrna Hurtado, Umesh T. Sankpal, Aboubacar Kaba, Shahela Mahammad, Jaya Chhabra, Deondra T. Brown, Raj K. Gurung, Alvin A. Holder, Jamboor K. Vishwanatha, Riyaz Basha
Publikováno v:
Cellular Physiology and Biochemistry, Vol 51, Iss 4, Pp 1894-1907 (2018)
Background/Aims: Targeting survivin, an anti-apoptotic protein and mitotic regulator, is considered as an effective therapeutic option for pancreatic cancer (PaCa). Tolfenamic acid (TA) showed anti-cancer activity in pre-clinical studies. A recent di
Externí odkaz:
https://doaj.org/article/969788d246ee461c8f63fba115110c42
Autor:
Jamboor K. Vishwanatha, Riyaz Basha, Umesh T. Sankpal, Aboubacar Kaba, Deondra T. Brown, Shahela Mahammad, Raj K. Gurung, Alvin A. Holder, Myrna Hurtado, Jaya Chhabra
Publikováno v:
Cellular Physiology and Biochemistry, Vol 51, Iss 4, Pp 1894-1907 (2018)
Background/Aims: Targeting survivin, an anti-apoptotic protein and mitotic regulator, is considered as an effective therapeutic option for pancreatic cancer (PaCa). Tolfenamic acid (TA) showed anti-cancer activity in pre-clinical studies. A recent di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef74adbe6070d7e31d4fab5ff5957312
https://doi.org/10.1159/000495715
https://doi.org/10.1159/000495715
Autor:
Laszlo Prokai, Riyaz Basha, Rajasekhar Maram, Blair Levesque, Myrna Hurtado, Alvin A. Holder, Raj K. Gurung, Jaya Chhabra, Jamboor K. Vishwanatha, Umesh T. Sankpal, Deondra T. Brown
Publikováno v:
Process Biochem
Anti-cancer activity of tolfenamic acid (TA) in preclinical models for pancreatic cancer (PaCa) is well established. Since the dosage for anti-cancer actions of TA is rather high, we recently demonstrated that IC(50) values of Copper-TA are 30–80%
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f599ad8ef43fea08b9793d13d847b7ce
https://europepmc.org/articles/PMC7384693/
https://europepmc.org/articles/PMC7384693/
Autor:
Jaya Chhabra, Rajasekhar Maram, Myrna Hurtado, Raj K. Gurung, Umesh T. Sankpal, Riyaz Basha, Jerry W. Simecka, Rafid Patel, Alvin A. Holder, Deondra T. Brown
Publikováno v:
Investigational new drugs. 37(1)
The non-steroidal anti-inflammatory drug, Tolfenamic acid (TA) acts as an anti-cancer agent in several adult and pediatric cancer models. Copper (Cu) is an important element with multiple biological functions and has gained interest in medical applic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::508293d7598118300242ca77606a7bc0
https://pubmed.ncbi.nlm.nih.gov/29761244
https://pubmed.ncbi.nlm.nih.gov/29761244
Autor:
Riyaz Basha, Alvin A. Holder, Umesh T. Sankpal, Laszlo Prokai, Rajasekhar Maram, Raj K. Gurung, Myrna Hurtado, Jaya Chhabra, Blair Levesque, Deondra T. Brown, Jamboor K. Vishwanatha
Publikováno v:
Cancer Research. 79:4811-4811
Anti-cancer activity of tolfenamic acid (TA) has been studied using several preclinical cancer models including pancreatic cancer (PaCa). Since the dosage used for the anti-cancer actions of TA is rather high, we investigated Copper-TA (Cu-TA) for an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a755743d1dc7a09d67f462b0ad6d184c
https://doi.org/10.1158/1538-7445.am2019-4811
https://doi.org/10.1158/1538-7445.am2019-4811
Autor:
Joseph Reitman, Amil Dudhia, Julie Hong, John K. Smith, Umesh T. Sankpal, Jaya Chhabra, Deondra T. Brown, Alvin A. Holder, Melissa Schullek, Nihant Tallapaka, Rassil Basha
Publikováno v:
Cancer Research. 79:2972-2972
Introduction. Medulloblastoma is the most common malignant brain tumor in children. New treatment strategies are urgently needed as the current options often result in significant long term neurocognitive and growth defects among survivors. We have p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e22883e61742b0b3e8c407422493e08c
https://doi.org/10.1158/1538-7445.am2019-2972
https://doi.org/10.1158/1538-7445.am2019-2972
Autor:
Yazmin Hernandez, Sarah Sarah Grebennikov, Emily Zakhary, Ashni Dudhia, Rajasekhar Maram, Diego Casanova, Umesh T. Sankpal, W. Paul Bowman, Deondra T. Brown, Jaya Chhabra, Alvin A. Holder, Riyaz M. Basha
Publikováno v:
Cancer Research. 79:2881-2881
Neuroblastoma (NB) is the most common extracranial solid tumor in infants and young children. NB often metastasizes to lymph nodes and bone marrow. When compared to low or intermediate risk tumors, high risk neuroblastoma (HRNB) is more aggressive wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4aa792b952521cb9ecf63273fe35feb0
https://doi.org/10.1158/1538-7445.am2019-2881
https://doi.org/10.1158/1538-7445.am2019-2881
Autor:
Raj K. Gurung, Deondra T. Brown, Riyaz Basha, Bianca Arechiga, Abigail Hunter, Umesh T Sankpal PhD, Jaya Chhabra, Alvin A. Holder, Rafid Patel
Publikováno v:
Cancer Research. 78:5424-5424
Clotam (tolfenamic acid or TA) is a nonsteroidal anti-inflammatory drug used to treat migraine headaches. Research from our laboratory and other groups has demonstrated that TA also acts as an anticancer agent in several adult and pediatric cancer mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9fdb26ceda2fae35c2376629df85a0a8
https://doi.org/10.1158/1538-7445.am2018-5424
https://doi.org/10.1158/1538-7445.am2018-5424