Zobrazeno 1 - 10
of 346
pro vyhledávání: '"Deok-ho Kim"'
Autor:
Soo Bin Lee, Ahmed Abdal Dayem, Sebastian Kmiecik, Kyung Min Lim, Dong Sik Seo, Hyeong-Taek Kim, Polash Kumar Biswas, Minjae Do, Deok-Ho Kim, Ssang-Goo Cho
Publikováno v:
Journal of Advanced Research, Vol 62, Iss , Pp 119-141 (2024)
Introduction: The stem cell microenvironment has been evidenced to robustly affect its biological functions and clinical grade. Natural or synthetic growth factors, especially, are essential for modulating stem cell proliferation, metabolism, and dif
Externí odkaz:
https://doaj.org/article/52b23fc16a9c48d3ac927e48273b9586
Autor:
Ahmed Abdal Dayem, Ellie Yan, Minjae Do, Yoojung Kim, Yeongseo Lee, Ssang-Goo Cho, Deok-Ho Kim
Publikováno v:
Nano Convergence, Vol 11, Iss 1, Pp 1-27 (2024)
Abstract Stem cell therapy holds promise for tissue regeneration, yet significant challenges persist. Emerging as a safer and potentially more effective alternative, extracellular vesicles (EVs) derived from stem cells exhibit remarkable abilities to
Externí odkaz:
https://doaj.org/article/950a2aa28ebe4d3f8f26703548bcb61d
Autor:
Yiyun Wang, Qizhi Qin, Ziyi Wang, Stefano Negri, Takashi Sono, Robert J. Tower, Zhao Li, Xin Xing, Mary Archer, Neelima Thottappillil, Manyu Zhu, Allister Suarez, Deok-Ho Kim, Tyler Harvey, Chen-Ming Fan, Aaron W. James
Publikováno v:
Cell Death and Disease, Vol 15, Iss 6, Pp 1-15 (2024)
Abstract The regeneration of the mammalian skeleton’s craniofacial bones necessitates the action of intrinsic and extrinsic inductive factors from multiple cell types, which function hierarchically and temporally to control the differentiation of o
Externí odkaz:
https://doaj.org/article/5800b8472f1d49b1972a215f61072512
Autor:
Zhanping Ren, Eun Hyun Ahn, Minjae Do, Devin B. Mair, Amir Monemianesfahani, Peter H. U. Lee, Deok-Ho Kim
Publikováno v:
npj Microgravity, Vol 10, Iss 1, Pp 1-10 (2024)
Abstract While the effects of microgravity on inducing skeletal muscle atrophy have been extensively studied, the impacts of microgravity on myogenesis and its mechanisms remain unclear. In this study, we developed a microphysiological system of engi
Externí odkaz:
https://doaj.org/article/fd5bdb1273714bb2a8541f436dddadac
Autor:
Amanda Krajnik, Erik Nimmer, Joseph A. Brazzo III, John C. Biber, Rhonda Drewes, Bat-Ider Tumenbayar, Andra Sullivan, Khanh Pham, Alanna Krug, Yuna Heo, John Kolega, Su-Jin Heo, Kwonmoo Lee, Brian R. Weil, Deok-Ho Kim, Sachin A. Gupte, Yongho Bae
Publikováno v:
APL Bioengineering, Vol 7, Iss 4, Pp 046104-046104-12 (2023)
Vascular dysfunction is a common cause of cardiovascular diseases characterized by the narrowing and stiffening of arteries, such as atherosclerosis, restenosis, and hypertension. Arterial narrowing results from the aberrant proliferation of vascular
Externí odkaz:
https://doaj.org/article/f176b2d325834adb81a32156d8050703
Autor:
Andrew Allan, Jeffery Creech, Christian Hausner, Peyton Krajcarski, Bianca Gunawan, Noah Poulin, Paul Kozlowski, Christopher Wayne Clark, Rachel Dow, Prakaimuk Saraithong, Devin B. Mair, Travis Block, Andre Monteiro da Rocha, Deok-Ho Kim, Todd J. Herron
Publikováno v:
iScience, Vol 26, Iss 7, Pp 107142- (2023)
Summary: hiPSC-CMs are being considered by the Food and Drug Administration and other regulatory agencies for in vitro cardiotoxicity screening to provide human-relevant safety data. Widespread adoption of hiPSC-CMs in regulatory and academic science
Externí odkaz:
https://doaj.org/article/f2569b96be304fcc8b3627f6cfc1e33e
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)
Abstract Water droplets sitting between wires are ubiquitous in nature and industry, often showing irregular (non-spherical) droplet shapes. To understand their topological singularity and evaporation mechanism, measuring volume changes of irregular
Externí odkaz:
https://doaj.org/article/764a13576e8240a1befa60af33ea61dd
Autor:
Taejoon Won, Megan K. Wood, David M. Hughes, Monica V. Talor, Zexu Ma, Jowaly Schneider, John T. Skinner, Beejan Asady, Erin Goerlich, Marc K. Halushka, Allison G. Hays, Deok-Ho Kim, Chirag R. Parikh, Avi Z. Rosenberg, Isabelle Coppens, Roger A. Johns, Nisha A. Gilotra, Jody E. Hooper, Andrew Pekosz, Daniela Čiháková
Publikováno v:
EBioMedicine, Vol 75, Iss , Pp 103812- (2022)
Summary: Background: Thromboembolism is a life-threatening manifestation of coronavirus disease 2019 (COVID-19). We investigated a dysfunctional phenotype of vascular endothelial cells in the lungs during COVID-19. Methods: We obtained the lung speci
Externí odkaz:
https://doaj.org/article/fa15652ffd1a47a2a1954f6284a33f0d
Autor:
Alec S. T. Smith, Changho Chun, Jennifer Hesson, Julie Mathieu, Paul N. Valdmanis, David L. Mack, Byung-Ok Choi, Deok-Ho Kim, Mark Bothwell
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Gene editing technologies hold great potential to enhance our ability to model inheritable neurodegenerative diseases. Specifically, engineering multiple amyotrophic lateral sclerosis (ALS) mutations into isogenic cell populations facilitates determi
Externí odkaz:
https://doaj.org/article/b867e9f17fc7469794bf34151937519a
Autor:
Jason W. Miklas, Elisa Clark, Shiri Levy, Damien Detraux, Andrea Leonard, Kevin Beussman, Megan R. Showalter, Alec T. Smith, Peter Hofsteen, Xiulan Yang, Jesse Macadangdang, Tuula Manninen, Daniel Raftery, Anup Madan, Anu Suomalainen, Deok-Ho Kim, Charles E. Murry, Oliver Fiehn, Nathan J. Sniadecki, Yuliang Wang, Hannele Ruohola-Baker
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-21 (2019)
Mutations in the gene HADHA result in mitochondrial tri-functional protein (MTP) deficiency and can result in sudden infant death syndrome for which there is no treatment. Here the authors show that the MTP deficient pathology in human cardiomyocytes
Externí odkaz:
https://doaj.org/article/eb9585b9475b4ec39e5021a1cc4c96fb