Zobrazeno 1 - 10 of 58 pro vyhledávání: '"Deok Yong, Sim"'
1
Akademický článek
Anti-Warburg Mechanism of Ginsenoside F2 in Human Cervical Cancer Cells via Activation of miR193a-5p and Inhibition of β-Catenin/c-Myc/Hexokinase 2 Signaling Axis
Autor: Nari Shin, Hyo-Jung Lee, Deok Yong Sim, Chi-Hoon Ahn, Su-Yeon Park, Wonil Koh, Jaeho Khil, Bum-Sang Shim, Bonglee Kim, Sung-Hoon Kim
Publikováno v: International Journal of Molecular Sciences, Vol 25, Iss 17, p 9418 (2024)
Though Ginsenoside F2 (GF2), a protopanaxadiol saponin from Panax ginseng, is known to have an anticancer effect, its underlying mechanism still remains unclear. In our model, the anti-glycolytic mechanism of GF2 was investigated in human cervical ca
Externí odkaz: https://doaj.org/article/ecd9694a58e24a31a3b5312e5f69590f
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2
Akademický článek
Apoptotic Effect of Isoimpertorin via Inhibition of c-Myc and SIRT1 Signaling Axis
Autor: Hwan-Joo Ko, Su-Yeon Park, Deok Yong Sim, Sung-Hoon Kim, Soyoung Hur, Jang-Hoon Lee, Youngchul Kim
Publikováno v: International Journal of Molecular Sciences, Vol 25, Iss 8, p 4248 (2024)
Though Isoimperatorin from Angelicae dahuricae is known to have antiviral, antidiabetic, anti-inflammatory and antitumor effects, its underlying antitumor mechanism remains elusive so far. Hence, the apoptotic mechanism of Isoimperatorin was explored
Externí odkaz: https://doaj.org/article/35c6cba81a2b4e9f8106d5d9ecad7140
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3
Akademický článek
Astragalus membranaceus Extract Induces Apoptosis via Generation of Reactive Oxygen Species and Inhibition of Heat Shock Protein 27 and Androgen Receptor in Prostate Cancers
Autor: Seok-Young Kim, Ji Eon Park, Hyo-Jung Lee, Deok Yong Sim, Chi-Hoon Ahn, Su-Yeon Park, Bum-Sang Shim, Bonglee Kim, Dae Young Lee, Sung-Hoon Kim
Publikováno v: International Journal of Molecular Sciences, Vol 25, Iss 5, p 2799 (2024)
Although Astragalus membranaceus is known to have anti-inflammatory, anti-obesity, and anti-oxidant properties, the underlying apoptotic mechanism of Astragalus membranaceus extract has never been elucidated in prostate cancer. In this paper, the apo
Externí odkaz: https://doaj.org/article/32af449851cb4e7aa74dac6e7da35974
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4
Akademický článek
The Apoptotic and Anti-Warburg Effects of Brassinin in PC-3 Cells via Reactive Oxygen Species Production and the Inhibition of the c-Myc, SIRT1, and β-Catenin Signaling Axis
Autor: Hyeon Hee Kwon, Chi-Hoon Ahn, Hyo-Jung Lee, Deok Yong Sim, Ji Eon Park, Su-Yeon Park, Bonglee Kim, Bum-Sang Shim, Sung-Hoon Kim
Publikováno v: International Journal of Molecular Sciences, Vol 24, Iss 18, p 13912 (2023)
Though Brassinin is known to have antiangiogenic, anti-inflammatory, and antitumor effects in colon, prostate, breast, lung, and liver cancers, the underlying antitumor mechanism of Brassinin is not fully understood so far. Hence, in the current stud
Externí odkaz: https://doaj.org/article/e2002c9572444fec8df51b783c69efe5
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5
Antioxidant-Based Preventive Effect of Phytochemicals on Anticancer Drug-Induced Hepatotoxicity
Autor: Ji Eon Park, Chi-Hoon Ahn, Hyo-Jung Lee, Deok Yong Sim, Su Yeon Park, Bonglee Kim, Bum Sang Shim, Dae Young Lee, Sung-Hoon Kim
Publikováno v: Antioxidants & Redox Signaling. 38:1101-1121
Drug induced liver injury (DILI) or hepatotoxicity has been a hot issue to overcome on the safety and physiological function of liver, since it is known to have biochemical, cellular, immunological and molecular alterations in liver mainly induced by
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2e474ac4d305c5139187e2b773e5cad
https://doi.org/10.1089/ars.2022.0144
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6
Akademický článek
The Antitumor Effect of Cinnamaldehyde Derivative CB-PIC in Hepatocellular Carcinoma Cells via Inhibition of Pyruvate and STAT3 Signaling
Autor: Hyungjin Kim, Hyo-Jung Lee, Deok Yong Sim, Ji Eon Park, Chi-Hoon Ahn, Su-Yeon Park, Eungyeong Jang, Bonglee Kim, Sung-Hoon Kim
Publikováno v: International Journal of Molecular Sciences, Vol 23, Iss 12, p 6461 (2022)
Though cinnamaldehyde derivative (CB-PIC), a major compound of cinnamon, is known to have anticancer activity, its underlying mechanism is not fully understood. In the present study, the anticancer mechanism of CB-PIC was investigated in human hepato
Externí odkaz: https://doaj.org/article/b70f0467ce38422792d7d77d98766ffe
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7
Akademický článek
Apoptotic and DNA Damage Effect of 1,2,3,4,6-Penta-O-galloyl-beta-D-glucose in Cisplatin-Resistant Non-Small Lung Cancer Cells via Phosphorylation of H2AX, CHK2 and p53
Autor: Ji-Hyun Kim, Eunji Im, Jihyun Lee, Hyo-Jung Lee, Deok Yong Sim, Ji Eon Park, Chi-Hoon Ahn, Hyeon Hee Kwon, Bum Sang Shim, Bonglee Kim, Sung-Hoon Kim
Publikováno v: Cells, Vol 11, Iss 8, p 1343 (2022)
Herein, the apoptotic mechanism of 1,2,3,4,6-penta-O-galloyl-β-D-glucopyranose (PGG) was examined in cisplatin-resistant lung cancer cells. PGG significantly reduced viability; increased sub-G1 accumulation and the number of terminal deoxynucleotidy
Externí odkaz: https://doaj.org/article/d927a0e7965d45cd951227a92a7fcc9d
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10
Akademický článek
Antitumor Effect of Morusin via G1 Arrest and Antiglycolysis by AMPK Activation in Hepatocellular Cancer
Autor: Ah-Reum Cho, Woon-Yi Park, Hyo-Jung Lee, Deok-Yong Sim, Eunji Im, Ji-Eon Park, Chi-Hoon Ahn, Bum-Sang Shim, Sung-Hoon Kim
Publikováno v: International Journal of Molecular Sciences, Vol 22, Iss 19, p 10619 (2021)
Though Morusin isolated from the root of Morus alba was known to have antioxidant, anti-inflammatory, antiangiogenic, antimigratory, and apoptotic effects, the underlying antitumor effect of Morusin is not fully understood on the glycolysis of liver
Externí odkaz: https://doaj.org/article/81c29cb01ec148118a5ef39322e84f82
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