Zobrazeno 1 - 10
of 138
pro vyhledávání: '"Deogratius Ssemwanga"'
Autor:
Maria Nannyonjo, Jonah Omooja, Daniel Lule Bugembe, Nicholas Bbosa, Sandra Lunkuse, Stella Esther Nabirye, Faridah Nassolo, Hamidah Namagembe, Andrew Abaasa, Anne Kazibwe, Pontiano Kaleebu, Deogratius Ssemwanga
Publikováno v:
Viruses, Vol 16, Iss 9, p 1454 (2024)
We assessed the performance and clinical relevance of Illumina MiSeq next-generation sequencing (NGS) for HIV-1 genotyping compared with Sanger sequencing (SS). We analyzed 167 participants, 45 with virologic failure (VL ≥ 1000 copies/mL), i.e., ca
Externí odkaz:
https://doaj.org/article/b792f59b6c27452286465c7b91a1fdb0
Autor:
Heather E. Grant, Sunando Roy, Rachel Williams, Helena Tutill, Bridget Ferns, Patricia A. Cane, J. Wilson Carswell, Deogratius Ssemwanga, Pontiano Kaleebu, Judith Breuer, Andrew J. Leigh Brown
Publikováno v:
Retrovirology, Vol 19, Iss 1, Pp 1-10 (2022)
Abstract We present 109 near full-length HIV genomes amplified from blood serum samples obtained during early 1986 from across Uganda, which to our knowledge is the earliest and largest population sample from the initial phase of the HIV epidemic in
Externí odkaz:
https://doaj.org/article/b9ce012fa63f4886844455303bb654f5
Autor:
Nicholas Bbosa, Deogratius Ssemwanga, Hamidah Namagembe, Ronald Kiiza, Jocelyn Kiconco, John Kayiwa, Tom Lutalo, Julius Lutwama, Alfred Ssekagiri, Isaac Ssewanyana, Susan Nabadda, Henry Kyobe-Bbosa, Jennifer Giandhari, Sureshnee Pillay, Upasana Ramphal, Yajna Ramphal, Yeshnee Naidoo, Derek Tshiabuila, Houriiyah Tegally, Emmanuel J. San, Eduan Wilkinson, Tulio de Oliveira, Pontiano Kaleebu
Publikováno v:
Emerging Infectious Diseases, Vol 28, Iss 5, Pp 1021-1025 (2022)
Genomic surveillance in Uganda showed rapid replacement of severe acute respiratory syndrome coronavirus 2 over time by variants, dominated by Delta. However, detection of the more transmissible Omicron variant among travelers and increasing communit
Externí odkaz:
https://doaj.org/article/c722de1348544f1c9e7a5461c191f850
Autor:
Jonah Omooja, Nicholas Bbosa, Dan Bugembe Lule, Maria Nannyonjo, Sandra Lunkuse, Faridah Nassolo, Stella Esther Nabirye, Hamidah Namagembe Suubi, Pontiano Kaleebu, Deogratius Ssemwanga
Publikováno v:
BMC Infectious Diseases, Vol 22, Iss 1, Pp 1-11 (2022)
Abstract Background HIV-1 drug resistance genotyping is critical to the monitoring of antiretroviral treatment. Data on HIV-1 genotyping success rates of different laboratory specimen types from multiple sources is still scarce. Methods In this cross
Externí odkaz:
https://doaj.org/article/57bd1d1319e241339db0c1b70caf5522
Autor:
Hassan W. Kayondo, Alfred Ssekagiri, Grace Nabakooza, Nicholas Bbosa, Deogratius Ssemwanga, Pontiano Kaleebu, Samuel Mwalili, John M. Mango, Andrew J. Leigh Brown, Roberto A. Saenz, Ronald Galiwango, John M. Kitayimbwa
Publikováno v:
BMC Bioinformatics, Vol 22, Iss 1, Pp 1-20 (2021)
Abstract Background Host population structure is a key determinant of pathogen and infectious disease transmission patterns. Pathogen phylogenetic trees are useful tools to reveal the population structure underlying an epidemic. Determining whether a
Externí odkaz:
https://doaj.org/article/f921303b4ec8402c97778b1b59c8ee53
Autor:
Tom Lutalo, Aminah Nalumansi, Denis Olara, John Kayiwa, Bernard Ogwang, Emmanuel Odwilo, Christine Watera, Stephen Balinandi, Jocelyn Kiconco, Joweria Nakaseegu, Jennifer Serwanga, Bernard Kikaire, Deogratius Ssemwanga, Brendah Abiko, Christopher Nsereko, Matthew Cotten, Joshua Buule, Julius Lutwama, Robert Downing, Pontiano Kaleebu
Publikováno v:
International Journal of Infectious Diseases, Vol 112, Iss , Pp 281-287 (2021)
Introduction: Serological testing is needed to better understand the epidemiology of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus. Rapid diagnostic tests (RDTs) have been developed to detect specific antibodies, IgM and IgG,
Externí odkaz:
https://doaj.org/article/0b0beca23d9d43df8d2c2299dac6f1d8
Autor:
Aminah Nalumansi, Tom Lutalo, John Kayiwa, Christine Watera, Stephen Balinandi, Jocelyn Kiconco, Joweria Nakaseegu, Denis Olara, Emmanuel Odwilo, Jennifer Serwanga, Bernard Kikaire, Deogratius Ssemwanga, Susan Nabadda, Isaac Ssewanyana, Diane Atwine, Henry Mwebesa, Henry Kyobe Bosa, Christopher Nsereko, Matthew Cotten, Robert Downing, Julius Lutwama, Pontiano Kaleebu
Publikováno v:
International Journal of Infectious Diseases, Vol 104, Iss , Pp 282-286 (2021)
Objectives: There is a high demand for SARS-CoV-2 testing to identify COVID-19 cases. Real-time quantitative PCR (qRT-PCR) is the recommended diagnostic test but a number of constraints prevent its widespread implementation, including cost. The aim o
Externí odkaz:
https://doaj.org/article/6110ea588c254119be122469409782e9
Autor:
Daniel Lule Bugembe, John Kayiwa, My V.T. Phan, Phiona Tushabe, Stephen Balinandi, Beatrice Dhaala, Jonas Lexow, Henry Mwebesa, Jane Aceng, Henry Kyobe, Deogratius Ssemwanga, Julius Lutwama, Pontiano Kaleebu, Matthew Cotten
Publikováno v:
Emerging Infectious Diseases, Vol 26, Iss 10, Pp 2411-2415 (2020)
We established rapid local viral sequencing to document the genomic diversity of severe acute respiratory syndrome coronavirus 2 entering Uganda. Virus lineages closely followed the travel origins of infected persons. Our sequence data provide an imp
Externí odkaz:
https://doaj.org/article/f9431989774d4a4aa45b08ff69fc09aa
Autor:
Emma Pujol-Hodge, Jesus F. Salazar-Gonzalez, Deogratius Ssemwanga, Edwin D. Charlebois, James Ayieko, Heather E. Grant, Teri Liegler, Katherine E. Atkins, Pontiano Kaleebu, Moses R. Kamya, Maya Petersen, Diane V. Havlir, Andrew J. Leigh Brown
Publikováno v:
Viruses, Vol 14, Iss 8, p 1673 (2022)
The Sustainable East Africa Research in Community Health (SEARCH) trial was a universal test-and-treat (UTT) trial in rural Uganda and Kenya, aiming to lower regional HIV-1 incidence. Here, we quantify breakthrough HIV-1 transmissions occurring durin
Externí odkaz:
https://doaj.org/article/3a26563fb65c4816806f3378346885d5
Autor:
Nicholas Bbosa, Deogratius Ssemwanga, Rebecca N. Nsubuga, Noah Kiwanuka, Bernard S. Bagaya, John M. Kitayimbwa, Alfred Ssekagiri, Gonzalo Yebra, Pontiano Kaleebu, Andrew Leigh-Brown
Publikováno v:
Viruses, Vol 13, Iss 6, p 970 (2021)
Phylogenetic inference is useful in characterising HIV transmission networks and assessing where prevention is likely to have the greatest impact. However, estimating parameters that influence the network structure is still scarce, but important in e
Externí odkaz:
https://doaj.org/article/fc3705248a3c450ba145d3a28aa79a71