Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Deog Young Choi"'
Publikováno v:
FEBS Open Bio, Vol 10, Iss 4, Pp 619-626 (2020)
Tobacco etch virus (TEV) protease is a 27‐kDa catalytic domain of the polyprotein nuclear inclusion a (NIa) in TEV, which recognizes the specific amino acid sequence ENLYFQG/S and cleaves between Q and G/S. Despite its substrate specificity, its us
Externí odkaz:
https://doaj.org/article/3c8ae464189d46d7b512875ebb3f2c59
Publikováno v:
FEBS Open Bio, Vol 10, Iss 4, Pp 619-626 (2020)
FEBS Open Bio
FEBS Open Bio
Tobacco etch virus (TEV) protease is a 27‐kDa catalytic domain of the polyprotein nuclear inclusion a (NIa) in TEV, which recognizes the specific amino acid sequence ENLYFQG/S and cleaves between Q and G/S. Despite its substrate specificity, its us
Autor:
Benjamin D. Drever, William G.L. Anderson, Gernot Riedel, Dong Hyun Kim, Jong Hoon Ryu, Deog-Young Choi, Bettina Platt
Publikováno v:
Journal of Pharmacological Sciences, Vol 107, Iss 4, Pp 380-392 (2008)
The precise causative factors in neurodegenerative diseases such as Alzheimer’s (AD) and Parkinson’s disease remain elusive, but mechanisms implicated comprise excitotoxicity, mitochondrial dysfunction, and in the case of AD, the amyloid beta pep
Externí odkaz:
https://doaj.org/article/b640bae7bb6340a4943b7263c5961710
Autor:
Jee-Yeon Noh, Joo Yong Lee, Tae In Kam, Huikyong Lee, Toshiyuki Nakagawa, Soo Jung Seo, Young-Yun Kong, Yong-Keun Jung, Deog-Young Choi, Hammou Oubrahim, Sang Mi Shim, Chul Woong Chung, Mei Ling Tai, Sungmin Song
Publikováno v:
The Journal of Cell Biology
Amyloid-beta (Abeta) neurotoxicity is believed to contribute to the pathogenesis of Alzheimer's disease (AD). Previously we found that E2-25K/Hip-2, an E2 ubiquitin-conjugating enzyme, mediates Abeta neurotoxicity. Here, we report that E2-25K/Hip-2 m
Autor:
Ki Dong Koo, Sang Won Seo, Jae-Ung Choi, Bettina Platt, Dongchul Lim, Deog-Young Choi, Hyo-Shin Kwak, Heuisul Park, Kyeongsik Min
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 18:2900-2904
We describe synthesis and evaluation of a series of cyclic urea derivatives with hydroxylethylamine isostere. Modification of P3, P1, and P2′ and combination of SAR display a >100-fold increase in potency with good cellular activity (IC50 = 0.15 μ
Autor:
Jong Hoon Ryu, William G.L. Anderson, Gernot Riedel, Benjamin D. Drever, Bettina Platt, Deog-Young Choi, Dong-Hyun Kim
Publikováno v:
Journal of Pharmacological Sciences, Vol 107, Iss 4, Pp 380-392 (2008)
The precise causative factors in neurodegenerative diseases such as Alzheimer’s (AD) and Parkinson’s disease remain elusive, but mechanisms implicated comprise excitotoxicity, mitochondrial dysfunction, and in the case of AD, the amyloid beta pep
Publikováno v:
Molecular and Cellular Biology. 21:2695-2705
In contrast to conventional signaling by growth factors that requires their continual presence, a 1-min pulse of nerve growth factor (NGF) is sufficient to induce electrical excitability in PC12 cells due to induction of the peripheral nerve type 1 (
Autor:
Simon Halegoua, Irene Ischenko, Juan José Toledo-Aral, Michael J. Hayman, Deog Young Choi, Gail Mandel, Patrick Safo, S. Rock Levinson, Hsien Y. Lin, Lillian Medina
Publikováno v:
The Journal of biological chemistry. 276(7)
Fibroblast growth factor receptors (FGFR) are widely expressed in many tissues and cell types, and the temporal expression of these receptors and their ligands play important roles in the control of development. There are four FGFR family members, FG
Autor:
Juan José Toledo-Aral, Gail Mandel, Baldomero M. Olivera, Anatoly Shcherbatko, Deog Young Choi, Edward B. Han, Tamara Rosenbaum, Paul Brehm, Patrick Safo
Publikováno v:
Scopus-Elsevier
The functional properties of most sodium channels are too similar to permit identification of specific sodium channel types underlying macroscopic current. Such discrimination would be particularly advantageous in the nervous system in which differen
Autor:
Drever, Benjamin D., Anderson, William G. L., Johnson, Helena, O'Callaghan, Matthew, Sangwon Seo, Deog-Young Choi, Riedel, Gernot, Platt, Bettina, Seo, Sangwon, Choi, Deog-Young
Publikováno v:
Journal of Alzheimer's Disease; 2007, Vol. 12 Issue 4, p319-333, 15p, 5 Graphs