Cardiovascular toxicities of immune therapies for cancer - a scientific statement of the Heart Failure Association (HFA) of the ESC and the ESC Council of Cardio-Oncology.

Autor: Tocchetti CG; Department of Translational Medical Sciences (DISMET), Center for Basic and Clinical Immunology Research (CISI), Interdepartmental Center of Clinical and Translational Sciences (CIRCET), Interdepartmental Hypertension Research Center (CIRIAPA), Federico II University, Naples, Italy., Farmakis D; Department of Cardiology, Attikon University Hospital, National and Kapodistrian University of Athens Medical School, Athens, Greece., Koop Y; Department of Cardiovascular Epidemiology, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.; Dutch Heart Foundation, The Hague, The Netherlands., Andres MS; Royal Brompton Hospital, Part of Guy's and St Thomas' NHS Foundation Trust, London, UK., Couch LS; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, John Radcliffe Hospital, University of Oxford, Oxford, UK., Formisano L; Department of Clinical Medicine and Surgery, Federico II University, Naples, Italy., Ciardiello F; Department of Precision Medicine, University of Campania 'Luigi Vanvitelli', Naples, Italy., Pane F; Department of Clinical Medicine and Surgery, Federico II University, Naples, Italy., Au L; Skin and Renal Unit, Royal Marsden NHS Foundation Trust, London, UK.; Department of Medical Oncology, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Melbourne, VIC, Australia., Emmerich M; The Francis Crick Institute, London, UK.; The Royal Marsden Hospital, London, UK.; St. John's Institute of Dermatology, Guy's and St Thomas' Hospital, London, UK., Plummer C; Department of Cardiology, Freeman Hospital, The Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK., Gulati G; Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway.; Department of Cardiology, Division of Medicine, Oslo University Hospital, Ullevål, Oslo, Norway.; Division of Research and Innovation, Akershus University Hospital, Lørenskog, Norway., Ramalingam S; Royal Brompton Hospital, Part of Guy's and St Thomas' NHS Foundation Trust, London, UK.; Oxted Health Centre, Oxted, UK., Cardinale D; CardioOncology Unit, European Institute of Oncology, IRCCS, Milan, Italy., Brezden-Masley C; Division of Medical Oncology, Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada., Iakobishvili Z; Department of Community Cardiology, Tel Aviv Jaffa District, Clalit Health Services, Tel Aviv, Israel.; Department of Cardiology, Assuta Ashdod University Hospital, Ashdod, Israel.; Faculty of Health Sciences, Ben Gurion University of the Negev, Be'er Sheva, Israel., Thavendiranathan P; Ted Rogers Program in Cardiotoxicity Prevention, Peter Munk Cardiac Center, Toronto General Hospital, University of Toronto, Toronto, ON, Canada., Santoro C; Department of Advanced Biomedical Science, Federico II University Hospital, Naples, Italy., Bergler-Klein J; Department of Cardiology, Medical University of Vienna, Vienna, Austria., Keramida K; Cardiology Department, General Anti-Cancer, Oncological Hospital, Agios Savvas, Athens, Greece., de Boer RA; Department of Cardiology, Erasmus Medical Center, Rotterdam, The Netherlands., Maack C; Department of Translational Research, Comprehensive Heart Failure Center (CHFC), University Clinic Würzburg, Würzburg, Germany.; Medical Clinic 1, University Clinic Würzburg, Würzburg, Germany., Lutgens E; Department of Cardiovascular Medicine and Immunology, Mayo Clinic, Rochester, MN, USA., Rassaf T; Department of Cardiology and Vascular Medicine, West German Heart and Vascular Center, University Hospital Essen, Essen, Germany., Fradley MG; Cardio-Oncology Center of Excellence, Division of Cardiology, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA., Moslehi J; Department of Medicine, University of California, San Francisco, San Francisco, CA, USA., Yang EH; UCLA Cardio-Oncology Program, Division of Cardiology, Department of Medicine, University of California, Los Angeles, Los Angeles, CA, USA., De Keulenaer G; Department of Pharmaceutical Sciences, University of Antwerp, Antwerp, Belgium., Ameri P; Department of Internal Medicine, University of Genova, Genoa, Italy.; IRCCS Ospedale Policlinico San Martino, Genoa, Italy., Bax J; Department of Cardiology, Leiden University Medical Centre, Leiden, The Netherlands., Neilan TG; Cardio-Oncology Program, Division of Cardiology, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Herrmann J; Cardio-Oncology Clinic, Division of Preventive Cardiology, Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA., Mbakwem AC; College of Medicine, University of Lagos/Lagos University Teaching Hospital Idi Araba, Lagos, Nigeria., Mirabel M; Cardiology, Institut Mutualiste Montsouris, Paris, France., Skouri H; Cardiology Division, Sheikh Shakhbout Medical City, Khalifa University, Abu Dhabi, UAE., Hirsch E; Department of Molecular Biotechnology and Health Sciences, Molecular Biotechnology Center, University of Turin, Turin, Italy., Cohen-Solal A; Paris Cité University INSERM U 948 MASCOT Research Unit Cardiology, Lariboisere Universitaire Hospital, AP-HP, Paris, France., Sverdlov AL; Newcastle Centre of Excellence in Cardio-Oncology, University of Newcastle, Hunter Medical Research Institute, Calvary Mater Newcastle, Hunter New England Health, Newcastle, NSW, Australia.; Cardiovascular Department, John Hunter Hospital, New Lambton Heights, NSW, Australia., van der Meer P; Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands., Asteggiano R; Internal Medicine, Department of Medicine and Surgery, University of Insubria, Varese, Italy.; LARC, Laboratorio Analisi e Ricerca Clinica, Turin, Italy., Barac A; Inova Schar Heart and Vascular Institute, Falls Church, VA, USA., Ky B; Division of Cardiology, Hospital of the University of Pennsylvania, Philadelphia, PA, USA., Lenihan D; Cape Cardiology, St Francis Healthcare, Cape Girardeau, MO, USA., Dent S; Duke Cancer Institute, Department of Medicine, Duke University, Durham, NC, USA., Seferovic P; University Medical Center, Medical Faculty University of Belgrade, Serbian Academy of Sciences and Arts, Belgrade, Serbia., Coats AJS; Heart Research Institute, Sydney, NSW, Australia., Metra M; Cardiology, ASST Spedali Civili, Department of Medical and Surgical Specialties, Radiological Sciences and Public Health, University of Brescia, Brescia, Italy., Rosano G; Department of Human Sciences and Promotion of Quality of Life, San Raffaele Open University of Rome, Rome, Italy.; Cardiology, San Raffaele Cassino Hospital, Cassino, FR, Italy., Suter T; Bern University Hospital, University of Bern, Bern, Switzerland., Lopez-Fernandez T; Cardio-Oncology Unit, Cardiology Department, IdiPAZ Research Institute, La Paz University Hospital, Madrid, Spain.; Cardiology Department, Quironsalud Madrid University Hospital, Madrid, Spain., Lyon AR; Cardio-Oncology Service, Royal Brompton Hospital and National Heart and Lung Institute, Imperial College London, London, UK.

Publikováno v: European journal of heart failure [Eur J Heart Fail] 2024 Oct; Vol. 26 (10), pp. 2055-2076. Date of Electronic Publication: 2024 Aug 01.

The right heart in patients with cancer. A scientific statement of the Heart Failure Association (HFA) of the ESC and the ESC Council of Cardio-Oncology.

Autor: Keramida K; Cardiology Department, General Anti-Cancer Oncological Hospital Agios Savvas, Athens, Greece., Farmakis D; Department of Cardiology, Athens University Hospital Attikon, National and Kapodistrian University of Athens Medical School, Athens, Greece., Rakisheva A; City Cardiological Center, Almaty, Kazakhstan, Qonaev City Hospital, Almaty Region, Almaty, Kazakhstan., Tocchetti CG; Department of Translational Medical Sciences (DISMET), 'Federico II' University, Naples, Italy.; Interdepartmental Center of Clinical and Translational Sciences (CIRCET), 'Federico II' University, Naples, Italy.; Interdepartmental Hypertension Research Center (CIRIAPA), 'Federico II' University, Naples, Italy.; Center for Basic and Clinical Immunology Research (CISI), 'Federico II' University, Naples, Italy., Ameri P; Department of Internal Medicine, University of Genova, Genoa, Italy.; IRCCS Ospedale Policlinico San Martino, Genoa, Italy., Asteggiano R; Internal Medicine, Department of Medicine and Surgery, University of Insubria, Varese, Italy.; LARC, Laboratorio Analisi e Ricerca Clinica, Turin, Italy., Barac A; MedStar Heart and Vascular Institute, Georgetown University, Washington, DC, USA., Bax J; Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands., Bayes-Genis A; CIBER Cardiovascular, Madrid, Spain.; Institut del Cor, Hospital Universitari Germans Trias i Pujol, Barcelona, Spain.; Department of Medicine, Universitat Autònoma de Barcelona, Barcelona, Spain.; Department of Cardiology, Medical University of Vienna, Vienna, Austria., Bergler Klein J; Department of Cardiology, Medical University of Vienna, Vienna, Austria., Bucciarelli-Ducci C; Royal Brompton and Harefield Hospital, London, UK., Celutkiene J; Centre of Cardiology and Angiology, Clinic of Cardiac and Vascular Diseases, Faculty of Medicine, Institute of Clinical Medicine, Vilnius University, Vilnius, Lithuania., Coats AJS; Heart Research Institute, Sydney, NSW, Australia., Cohen Solal A; Université Paris Cité, INSERM U-942 MASCOT, Cardiology Department, Lariboisière Hospital, Paris, France., Dent S; Duke Cancer Institute, Department of Medicine, Duke University, Durham, NC, USA., Filippatos G; Department of Cardiology, Athens University Hospital Attikon, National and Kapodistrian University of Athens Medical School, Athens, Greece., Ghosh A; Barts Heart Centre, University College London Hospital and Hatter Cardiovascular Institute, London, UK., Hermann J; Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA., Koop Y; Department of Cardiology, Radboud University Medical Center, Nijmegen, The Netherlands., Lenihan D; Cardio-Oncology Program, St Francis Healthcare, Cape Girardeau, MO, USA., Lopez Fernandez T; Cardiology Department, La Paz University Hospital, IdiPAZ Research Institute, Madrid, Spain.; Cardiology Department, Hospital Universitario Quirónsalud Madrid, Madrid, Spain., Lyon AR; National Heart and Lung Institute, Imperial College London and Cardio-Oncology Service, Royal Brompton Hospital, London, UK., Mercurio V; Department of Translational Medical Sciences (DISMET), 'Federico II' University, Naples, Italy.; Interdepartmental Center of Clinical and Translational Sciences (CIRCET), 'Federico II' University, Naples, Italy.; Interdepartmental Hypertension Research Center (CIRIAPA), 'Federico II' University, Naples, Italy., Moura B; Armed Forces Hospital, Porto and Faculty of Medicine of the University of Porto, Porto, Portugal., Piepoli M; Clinical Cardiology, IRCCS Policlinico San Donato, Milan, Italy.; Department of Biomedical Sciences for Health, University of Milan, Milan, Italy., Sener YZ; Cardiology Department, Beypazarı State Hospital, Ankara, Turkey., Suter T; Cardiology Department, University of Ulm, Ulm, Germany., Sverdlov AL; Newcastle Centre of Excellence in Cardio-Oncology, The University of Newcastle, Hunter Medical Research Institute, Calvary Mater Newcastle, Hunter New England Health, Newcastle, NSW, Australia.; Cardiovascular Department, John Hunter Hospital, New Lambton Heights, NSW, Australia., Tadic M; Klinik für Innere Medizin II, Universitätsklinikum Ulm, Ulm, Germany., Thum T; Institute of Molecular and Translational Therapeutic Strategies (IMTTS), Hannover Medical School, Hannover, Germany.; Fraunhofer Cluster of Excellence Immune-Mediated Diseases (CIMD), Hannover, Germany.; Fraunhofer Institute for Toxicology and Experimental Medicine (ITEM), Hannover, Germany., van der Meer P; Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands., van Linthout S; Berlin Institute of Health (BIH) at Charité, BIH Center for Regenerative Therapies, Berlin, Germany.; German Center for Cardiovascular Research (DZHK), partner site Berlin, Berlin, Germany., Metra M; Institute of Cardiology, ASST Spedali Civili, Department of Medical and Surgical Specialties, Radiological Sciences and Public Health, University of Brescia, Brescia, Italy., Rosano G; Cardiology, San Raffaele Cassino, Cassino, Italy.

Publikováno v: European journal of heart failure [Eur J Heart Fail] 2024 Oct; Vol. 26 (10), pp. 2077-2093. Date of Electronic Publication: 2024 Aug 28.

A boy with Japanese Dent’s disease exhibiting abnormal calcium metabolism and osseous disorder of the spine: defective megalin expression at the brushborder of renal proximal tubules

Autor: M Ikeoka, Tsukasa Takemura, Hiroaki Kuwajima, Norihisa Wada, Hidehiko Yanagida, Mitsuru Okada, Nobutada Tabata, Keisuke Sugimoto

Publikováno v: Clinical Nephrology. 62:306-312

We encountered a 16-year-old boy with Japanese Dent's disease who exhibited renal insufficiency and an osseous disorder of the spine. Proteinuria first was noted at the age of 2 years. At 13 years, the patient underwent analysis of the CLCN5 gene, wh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7debe8d6f236f5c80134221839e345c7
https://doi.org/10.5414/cnp62306

Breast cancer and cardiovascular health.

Autor: López-Fernández T; Cardiology Department, La Paz University Hospital, IdiPAZ Research Institute, C/Paseo de la Castellana n° 261, 28046 Madrid, Spain.; Cardiology Department, Quironsalud University Hospital, C. Diego de Velázquez, 1, 28223 Pozuelo de Alarcón, Madrid, Spain., Marco I; Cardiology Department, La Paz University Hospital, IdiPAZ Research Institute, C/Paseo de la Castellana n° 261, 28046 Madrid, Spain., Aznar MC; Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK., Barac A; Inova ScharHeart and Vascular, Inova Schar Cancer Institute, Fall Church, VA, USA., Bergler-Klein J; Department of Cardiology, University Clinic of Internal Medicine II, Medical University of Vienna, Vienna, Austria., Meattini I; Department of Experimental and Clinical Biomedical Sciences 'M. Serio', Azienda Ospedaliero-Universitaria Careggi, Florence, Italy., Scott JM; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Cardinale D; Cardioncology Unit, European Institute of Oncology, I.R.C.C.S., Milan, Italy., Dent S; Wilmot Cancer Institute, Department of Medicine, University of Rochester, Rochester, NY, USA.

Publikováno v: European heart journal [Eur Heart J] 2024 Nov 07; Vol. 45 (41), pp. 4366-4382.

Estrogen signaling suppresses tumor-associated tissue eosinophilia to promote breast tumor growth.

Autor: Artham S; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, NC, USA., Juras PK; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, NC, USA., Goyal A; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, NC, USA., Chakraborty P; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Byemerwa J; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, NC, USA., Liu S; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Wardell SE; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, NC, USA., Chakraborty B; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, NC, USA., Crowder D; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, NC, USA., Lim F; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, NC, USA., Strawser CH; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, NC, USA., Newlin M; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, NC, USA., Racioppi A; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, NC, USA., Dent S; Division of Medical Oncology, Department of Medicine, Duke University School of Medicine, Durham, NC, USA., Mirminachi B; Division of Gastroenterology, Department of Medicine, Duke University School of Medicine, Durham, NC, USA., Roper J; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, NC, USA.; Division of Gastroenterology, Department of Medicine, Duke University School of Medicine, Durham, NC, USA., Perou CM; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Chang CY; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, NC, USA., McDonnell DP; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, NC, USA.

Publikováno v: Science advances [Sci Adv] 2024 Sep 27; Vol. 10 (39), pp. eadp2442. Date of Electronic Publication: 2024 Sep 27.