Pharmacokinetics of tenofovir alafenamide with and without cobicistat in pregnant and postpartum women living with HIV

Autor: Brooks, Kristina M, Momper, Jeremiah D, Pinilla, Mauricio, Stek, Alice M, Barr, Emily, Weinberg, Adriana, Deville, Jaime G, Febo, Irma L, Cielo, Mikhaela, George, Kathleen, Denson, Kayla, Rungruengthanakit, Kittipong, Shapiro, David E, Smith, Elizabeth, Chakhtoura, Nahida, Rooney, James F, Haubrich, Richard, Espina, Rowena, Capparelli, Edmund V, Mirochnick, Mark, Best, Brookie M, IMPAACT P1026s Protocol Team

Publikováno v: AIDS (London, England), vol 35, iss 3

ObjectiveTo evaluate the pharmacokinetics of tenofovir alafenamide (TAF) 10 mg with cobicistat and 25 mg without boosting in pregnant and postpartum women with HIV and to characterize TAF placental transfer and infant washout pharmacokinetics.DesignO

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::a38c10be3807b7c1f344a4e1bce7f9c2
https://escholarship.org/uc/item/2tx9b5jn

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PHARMACOKINETICS AND SAFETY OF RALTEGRAVIR IN 2 to 12 YEAR OLD CHILDREN WITH HIV RECEIVING RIFAMPICIN FOR TUBERCULOSIS

Autor: MEYERS, Tammy, SAMSON, Pearl, ACOSTA, Edward P, MOYE, Jack, TOWNLEY, Ellen, BRADFORD, Sarah, MARILLO, Linda, DENSON, Kayla, HOVIND, Laura, SISE, Thucuma, TEPPLER, Hedy, MATHIBA, Sisinyana Ruth, MASENYA, Masebole, HESSELING, Anneke, COTTON, Mark F, KROGSTAD, Paul

Publikováno v: AIDS

Drug-drug interactions limit current antiretroviral treatment options for HIV-infected children with tuberculosis (TB). Rifampicin (RIF) induces UDP-glucuronosyltransferase activity, accelerating the clearance of raltegravir (RAL). We sought to estab

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4352e60b5ea87dd8392f71064da6a598
https://europepmc.org/articles/PMC7232968/

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Loss of KIBRA function activates EGFR signaling by inducing AREG.

Autor: Mussell AL; Department of Cancer Genetics & Genomics, Roswell Park Cancer Institute, Buffalo, NY, USA., Denson KE; Department of Cancer Genetics & Genomics, Roswell Park Cancer Institute, Buffalo, NY, USA.; Current address: Frontier Science Foundation, Amherst, NY, USA., Shen H; Department of Cancer Genetics & Genomics, Roswell Park Cancer Institute, Buffalo, NY, USA., Chen Y; Department of Cancer Genetics & Genomics, Roswell Park Cancer Institute, Buffalo, NY, USA., Yang N; Department of Anesthesiology, Jacobs School of Medicine & Biomedical Sciences, University at Buffalo, The State University of New York, Buffalo, NY, USA., Frangou C; Harvard T.H. Chan School of Public Health, Molecular and Integrative Physiological Sciences, Boston, MA, USA., Zhang J; Department of Cancer Genetics & Genomics, Roswell Park Cancer Institute, Buffalo, NY, USA.

Publikováno v: Oncotarget [Oncotarget] 2018 Jul 06; Vol. 9 (52), pp. 29975-29984. Date of Electronic Publication: 2018 Jul 06 (Print Publication: 2018).