Zobrazeno 1 - 10
of 155
pro vyhledávání: '"Denny D. Watson"'
Publikováno v:
J Nucl Cardiol
BACKGROUND: Patients who achieve ≥10 METS during exercise SPECT myocardial perfusion imaging (MPI) have very low rates of significant ischemia and major adverse cardiac events (MACE). It is unknown how many older adults can achieve ≥10 METS, and
Autor:
Denny D. Watson, Christopher M. Belyea, George A. Beller, George T. Charlton, Benjamin H. Holland, Jamieson M. Bourque
Publikováno v:
Journal of Nuclear Cardiology. 18:230-237
The benefit of myocardial perfusion imaging (MPI) over exercise ECG stress testing alone is unclear in individuals attaining a workload of ≥10 METS. The purpose of this prospective study is to determine mortality and nonfatal cardiac events in pati
Publikováno v:
Journal of the American College of Cardiology. 54:538-545
Objectives We sought to identify prospectively the prevalence of significant ischemia (≥10% of the left ventricle [LV]) on exercise single-photon emission computed tomography (SPECT) imaging relative to workload achieved in consecutive patients ref
Autor:
William H. Smith, Denny D. Watson
Publikováno v:
Journal of Nuclear Cardiology. 14:466-482
Measurement of regional myocardial tracer concentration after stress and at rest allows the establishment of normal standards for myocardial perfusion and reversibility and provides a reference from which to determine disease severity and change in r
Autor:
Denny D. Watson, Joel Linden, Timothy L. Macdonald, Kazuya Takehana, Frank D. Petruzella, George A. Beller, Jayson M. Rieger, David K. Glover, Mirta Ruiz
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 292:H3164-H3171
We sought to determine whether administration of a very low, nonvasodilating dose of a highly selective adenosine A2A receptor agonist (ATL-193 or ATL-146e) would be cardioprotective in a canine model of myocardial stunning produced by multiple episo
Autor:
Ajit Raisinghani, Paul-Andre de Lame, Denny D. Watson, Paul Kligfield, George A. Beller, C. Richard Conti, Michele L. Lemaire, Andrew D. Michaels, Ozlem Soran
Publikováno v:
American Heart Journal. 150:1066-1073
Enhanced external counterpulsation (EECP) reduces angina and extends time to exercise-induced ischemia in patients with symptomatic coronary disease. One- and two-center studies and a retrospective case series reported that EECP improves myocardial p
Autor:
George A. Beller, Timothy L. Macdonald, David K. Glover, Mirta Ruiz, Jayson M. Rieger, Denny D. Watson, Gail W. Sullivan, Laurent Riou, Joel Linden
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 288:H1851-H1858
Adenosine and adenosine A2Areceptor agonists have been shown to limit myocardial infarct size when given at vasodilatory doses during reperfusion. This beneficial effect is thought to be due, in part, to stimulation of adenosine A2Areceptors on infla
Autor:
George A. Beller, Denny D. Watson
Publikováno v:
Journal of the American College of Cardiology. 43(2):209-212
A large amount of data has accumulated during the past 20 years demonstrating the value of exercise or pharmacologic stress planar and single-photon emission-computed tomographic (SPECT) perfusion imaging for risk stratification and prognostication i
Autor:
Kazuya Takehana, George A. Beller, Denny D. Watson, David K. Glover, Mirta Ruiz, Frank D. Petruzella
Publikováno v:
Journal of Nuclear Cardiology. 10:375-384
We sought to determine whether a dual-isotope imaging strategy (rest thallium 201/stress technetium 99m sestamibi) might be useful for assessing myocardial viability and residual ischemia in the infarct zone very early after reperfusion.Fifteen open-
Autor:
Denny D. Watson, George A. Beller, Timothy L. Macdonald, Mirta Ruiz, Joel Linden, Laurent Riou, Jayson M. Rieger, David K. Glover
Publikováno v:
Journal of the American College of Cardiology. 40:1687-1694
ObjectivesThe study was done to determine the effects of propranolol, enalaprilat, verapamil, and caffeine on the vasodilatory properties of the adenosine A2A-receptor agonist ATL-146e (ATL).BackgroundATL is a new adenosine A2A-receptor agonist propo