Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Dennisse V. Jimenez"'
Autor:
Peter Andersen, Emmanouil Tampakakis, Dennisse V. Jimenez, Suraj Kannan, Matthew Miyamoto, Hye Kyung Shin, Amir Saberi, Sean Murphy, Edrick Sulistio, Stephen P. Chelko, Chulan Kwon
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
The heart arises from distinct progenitor cells of both the first and second heart fields (FHF and SHF). Here, the authors generated precardiac organoids from mouse and human pluripotent cells and show that FHF and SHF cells form similarly to their i
Externí odkaz:
https://doaj.org/article/4409cf8489414ab6a468a5e03fc7c274
Autor:
Emmanouil Tampakakis, Dennisse V. Jimenez, Peter Andersen, Edrick Sulistio, Sean Murphy, Suraj Kannan, Chulan Kwon, Stephen P. Chelko, Amir Saberi, Matthew Miyamoto, Hye Kyung Shin
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Nature Communications
Nature Communications
The discovery of the first heart field (FHF) and the second heart field (SHF) led us to understand how cardiac lineages and structures arise during development. However, it remains unknown how they are specified. Here, we generate precardiac spheroid
Autor:
Aundrea F. Bartley, Robert E. Sorge, Kazu Nakazawa, Kazuhito Nakao, Emily L Farmer-Alroth, Yuko Fujita, Kenji Hashimoto, Keri Martinowich, Stefan Kolata, Vivek Jeevakumar, Dennisse V. Jimenez, Sunny Zhihong Jiang, Lynn E. Dobrunz, Gregory R. Rompala, Yolanda Mateo
Publikováno v:
Neuropsychopharmacology
Whereas cortical GAD67 reduction and subsequent GABA level decrease are consistently observed in schizophrenia and depression, it remains unclear how these GABAergic abnormalities contribute to specific symptoms. We modeled cortical GAD67 reduction i
Autor:
Mahima Sukumar, Keri Martinowich, Kristen R. Maynard, Robert J. Schloesser, Dennisse V. Jimenez, John W Hobbs, Alisha Kardian
Publikováno v:
Brain Structure and Function. 222:3295-3307
Brain-derived neurotrophic factor (BDNF) is an activity-dependent neurotrophin critical for neuronal plasticity in the hippocampus. BDNF is encoded by multiple transcripts with alternative 5′ untranslated regions (5′UTRS) that display activity-in
Autor:
Marcelo Diaz-Bustamante, Dennisse V. Jimenez, Keri Martinowich, Ahmad Jalloh, Briony J. Catlow, Daniel Paredes, Amritha Jaishankar, Ronald D.G. McKay, Seungmae Seo, Daniel J. Hoeppner
Publikováno v:
Brain Research. 1754:147254
Schizophrenia is a neurodevelopmental psychiatric disorder, encompassing genetic and environmental risk factors. For several decades, investigators have been implementing the use of lesions of the neonatal rodent hippocampus to model schizophrenia, r
Autor:
Keri Martinowich, Yishan Mai, Brady J. Maher, Nicholas F. Hardy, Kristen R. Maynard, Julia L. Hill, Henry L. Hallock, Feng Yang, Robert J. Schloesser, Ming Ren, Dennisse V. Jimenez, Huei Ying Chen
Publikováno v:
Brain structurefunction. 224(1)
Signaling of brain-derived neurotrophic factor (BDNF) via tropomyosin receptor kinase B (TrkB) plays a critical role in the maturation of cortical inhibition and controls expression of inhibitory interneuron markers, including the neuropeptide cortis
Autor:
Denis J. David, Mahima Sukumar, Robert J. Schloesser, Kristen R. Maynard, Nicholas F. Hardy, Alain M. Gardier, Husseini K. Manji, Sophie Orvoen, Keri Martinowich, Dennisse V. Jimenez
Publikováno v:
Brain Stimulation, Vol 8, Iss 5, Pp 862-867 (2015)
Background Neurogenesis continues throughout life in the hippocampal dentate gyrus. Chronic treatment with monoaminergic antidepressant drugs stimulates hippocampal neurogenesis, and new neurons are required for some antidepressant-like behaviors. El
Autor:
Kuan Hong Wang, Ming Ren, Surjeet Mastwal, Charles R. Gerfen, Keri Martinowich, Dennisse V. Jimenez, Yizhou Ye
Publikováno v:
Journal of Neuroscience. 34:9484-9496
The mesofrontal dopaminergic circuit, which connects the midbrain motivation center to the cortical executive center, is engaged in control of motivated behaviors. In addition, deficiencies in this circuit are associated with adolescent-onset psychia
Autor:
Dennisse V. Jimenez, Husseini K. Manji, Robert J. Schloesser, Ronald D. G. McKay, Keri Martinowich, Daniel Paredes, Nicholas F. Hardy, Briony J. Catlow
Publikováno v:
Brain Structure and Function. 219:1139-1148
Following their birth in the adult hippocampal dentate gyrus, newborn progenitor cells migrate into the granule cell layer where they differentiate, mature, and functionally integrate into existing circuitry. The hypothesis that adult hippocampal neu
Autor:
Dennisse V. Jimenez, Keri Martinowich, Cameron Pollock, Robert J. Schloesser, Alisha Kardian, Julia L. Hill, Nicholas F. Hardy, Kristen R. Maynard
Publikováno v:
Translational Psychiatry
Posttraumatic stress disorder is characterized by hyperarousal, sensory processing impairments, sleep disturbances and altered fear regulation; phenotypes associated with changes in brain oscillatory activity. Molecules associated with activity-depen