Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Dennis Z.-M. Wang"'
Autor:
Dennis Z.-M. Wang, Sathivel Ponniah, Catherine J. Pallen, Raymond M.H. Teng, Xiaoning Si, Kenneth F. Ryan, Li Zeng, Kwok Peng Ng, Wei-Ping Yu, Hoa Thi Le
Publikováno v:
The Journal of Cell Biology
We investigated the molecular and cellular actions of receptor protein tyrosine phosphatase (PTP) alpha in integrin signaling using immortalized fibroblasts derived from wild-type and PTP alpha-deficient mouse embryos. Defects in PTP alpha-/- migrati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::687159c74d346a6b39d9bdf740466b6e
https://doi.org/10.1083/jcb.200206049
https://doi.org/10.1083/jcb.200206049
Autor:
Sathivel Ponniah, Thomas Doetschman, Matthew R. Skelton, Catherine J. Pallen, Dennis Z.-M. Wang, Charles V. Vorhees
Publikováno v:
Brain research. 984(1-2)
Receptor PTPalpha is a widely expressed transmembrane enzyme enriched in brain. PTPalpha knockout (PTPalpha(-/-)) mice are viable and display no gross abnormalities. Brain and embryo derived fibroblast src and fyn activity is reduced to50% in PTPalph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d996993383537396f253ee32336e2634
https://pubmed.ncbi.nlm.nih.gov/12932834
https://pubmed.ncbi.nlm.nih.gov/12932834
Autor:
John W. McAvoy, Ivan Bertoncello, David D.L. Bowtell, Dennis Z.-M. Wang, Helen E. Abud, Vicki E. Hammond
Publikováno v:
Genesdevelopment. 11(3)
We have investigated the role of the mammalian Son of sevenless 1 (Sos1) protein in growth factor signaling in vivo by generating mice and cell lines that lacked the Sos1 protein. Homozygous null embryos were smaller than normal, died mid-gestation w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80d658d49200a4accb70cb930809b0c3
https://pubmed.ncbi.nlm.nih.gov/9030684
https://pubmed.ncbi.nlm.nih.gov/9030684
Publikováno v:
Australian and New Zealand journal of medicine. 25(6)
The last five years have seen a rapid increase in interest and understanding of signal transduction pathways. While the description of such pathways has become more detailed and complex, a number of consistent findings have emerged. Modular domains,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9160d0b49f78e8d407ab09c087e63fe7
https://pubmed.ncbi.nlm.nih.gov/8770362
https://pubmed.ncbi.nlm.nih.gov/8770362
Publikováno v:
European journal of biochemistry. 232(3)
Ras GTPase-activating protein of 120 kDa (p120GAP) consists of a hydrophobic Gly-Ala-Pro-rich stretch and src homology 2 and 3 (SH2/SH3) domains in the N-terminal half, and a Ras GTPase-activating domain at the C-terminus. In order to evaluate the po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dff8bde0cd03538287668d47a9fa813d
https://pubmed.ncbi.nlm.nih.gov/7588705
https://pubmed.ncbi.nlm.nih.gov/7588705
Publikováno v:
Current Biology. (10):535-S1
A role for the receptor-like protein tyrosine phosphatase alpha (PTPalpha) in regulating the kinase activity of Src family members has been proposed because ectopic expression of PTPalpha enhances the dephosphorylation and activation of Src and Fyn [
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e3dea852461e8164bae93d6fa58f1e4