Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Dennis Y. Gout"'
Publikováno v:
Gout, D Y, Groen, L S & van Egmond, M 2022, ' The present and future of immunocytokines for cancer treatment ', Cellular and Molecular Life Sciences, vol. 79, no. 10, 509 . https://doi.org/10.1007/s00018-022-04514-9
Monoclonal antibody (mAb) therapy has successfully been introduced as treatment of several lymphomas and leukemias. However, solid tumors reduce the efficacy of mAb therapy because of an immune-suppressive tumor micro-environment (TME), which hampers
Autor:
Marieke H. Heineke, Paula J. Winter, Niels Heemskerk, Suzanne N. Lissenberg-Thunnissen, Marco de Donatis, Dennis Y. Gout, A. Robin Temming, Cornelis W. Tuk, Thies Rösner, Marijn Bögels, Tessa Hellingman, Mandy Gruijs, Marjolein van Egmond, Jantine E. Bakema, Arthur E. H. Bentlage, Gestur Vidarsson, Thomas Valerius
Publikováno v:
Journal of Clinical Investigation, 131(6), 1. The American Society for Clinical Investigation
J Clin Invest
Heemskerk, N, Gruijs, M, Temming, A R, Heineke, M H, Gout, D Y, Hellingman, T, Tuk, C W, Winter, P J, Lissenberg-Thunnissen, S, Bentlage, A E, de Donatis, M, Bögels, M, Rösner, T, Valerius, T, Bakema, J E, Vidarsson, G & van Egmond, M 2021, ' Augmented antibody-based anticancer therapeutics boost neutrophil cytotoxicity ', Journal of Clinical Investigation, vol. 131, no. 6, e134680 . https://doi.org/10.1172/JCI134680
Journal of Clinical Investigation, 131(6):e134680. The American Society for Clinical Investigation
Journal of clinical investigation, 131(6):e134680. The American Society for Clinical Investigation
J Clin Invest
Heemskerk, N, Gruijs, M, Temming, A R, Heineke, M H, Gout, D Y, Hellingman, T, Tuk, C W, Winter, P J, Lissenberg-Thunnissen, S, Bentlage, A E, de Donatis, M, Bögels, M, Rösner, T, Valerius, T, Bakema, J E, Vidarsson, G & van Egmond, M 2021, ' Augmented antibody-based anticancer therapeutics boost neutrophil cytotoxicity ', Journal of Clinical Investigation, vol. 131, no. 6, e134680 . https://doi.org/10.1172/JCI134680
Journal of Clinical Investigation, 131(6):e134680. The American Society for Clinical Investigation
Journal of clinical investigation, 131(6):e134680. The American Society for Clinical Investigation
Most clinically used anticancer mAbs are of the IgG isotype, which can eliminate tumor cells through NK cell-mediated antibody-dependent cellular cytotoxicity and macrophage-mediated antibody-dependent phagocytosis. IgG, however, ineffectively recrui
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::253c7d45fb6c5b38d74a0986dbf8bca1
https://dspace.library.uu.nl/handle/1874/425229
https://dspace.library.uu.nl/handle/1874/425229
Autor:
Diana van den Heuvel, Annelotte P. Wondergem, Dennis Y. Gout, Katja Apelt, Iris Zoutendijk, Martijn S. Luijsterburg
Publikováno v:
Scientific Reports, 10(1). NATURE PUBLISHING GROUP
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports
Transcription-coupled repair (TCR) removes DNA lesions from the transcribed strand of active genes. Stalling of RNA polymerase II (RNAPII) at DNA lesions initiates TCR through the recruitment of the CSB and CSA proteins. The full repertoire of protei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12c402ddeaa1898ffc6b0afe914fc5ee
http://hdl.handle.net/1887/3184395
http://hdl.handle.net/1887/3184395
SummaryTranscription-coupled repair (TCR) removes DNA lesions from the transcribed strand of active genes. Stalling of RNA polymerase II (RNAPII) at DNA lesions initiates TCR through the recruitment of the CSB and CSA proteins. The full repertoire of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85c059105f132d90ec439dbd7349ec96