Transcription regulation by CarD in mycobacteria is guided by basal promoter kinetics

Autor: Dennis X. Zhu, Christina L. Stallings

Publikováno v: bioRxiv

Bacterial pathogens likeMycobacterium tuberculosis(Mtb) employ transcription factors to adapt their physiology to the diverse environments within their host. CarD is a conserved bacterial transcription factor that is essential for viability inMtb. Un

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0175a68ec95cf10e24ec774d81384a8
https://doi.org/10.1101/2023.03.16.533025

CarD contributes to diverse gene expression outcomes throughout the genome of Mycobacterium tuberculosis

Autor: Dennis X. Zhu, Ashley L. Garner, Christina L. Stallings, Eric A. Galburt

Publikováno v: Proceedings of the National Academy of Sciences. 116:13573-13581

The ability to regulate gene expression through transcription initiation underlies the adaptability and survival of all bacteria. Recent work has revealed that the transcription machinery in many bacteria diverges from the paradigm that has been esta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4a7a819d251b7ff270479f26a44f95c8
https://doi.org/10.1073/pnas.1900176116

Perspectives and Advances in the Understanding of Tuberculosis

Autor: Anne E. Mayer Bridwell, Christina L. Stallings, Gregory A. Harrison, Jerome Prusa, Dennis X. Zhu, Rachel L. Kinsella, Sthefany M. Chavez

Publikováno v: Annual review of pathology. 16

Mycobacterium tuberculosis ( Mtb), the causative agent of tuberculosis (TB), remains a leading cause of death due to infection in humans. To more effectively combat this pandemic, many aspects of TB control must be developed, including better point o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::def5cc654702f9d92d7444b2c5ad4877
https://pubmed.ncbi.nlm.nih.gov/33497258

Chemical disarming of isoniazid resistance in

Autor: Kelly, Flentie, Gregory A, Harrison, Hasan, Tükenmez, Jonathan, Livny, James A D, Good, Souvik, Sarkar, Dennis X, Zhu, Rachel L, Kinsella, Leslie A, Weiss, Samantha D, Solomon, Miranda E, Schene, Mette R, Hansen, Andrew G, Cairns, Martina, Kulén, Torbjörn, Wixe, Anders E G, Lindgren, Erik, Chorell, Christoffer, Bengtsson, K Syam, Krishnan, Scott J, Hultgren, Christer, Larsson, Fredrik, Almqvist, Christina L, Stallings

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America. 116(21)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0f95775346e9eccdc954e92cd619078b
https://pubmed.ncbi.nlm.nih.gov/31176512

De novo transcriptome assembly of Pueraria montana var. lobata and Neustanthus phaseoloides for the development of eSSR and SNP markers:narrowing the US origin(s) of the invasive kudzu

Autor: Jeff J. Doyle, Keith A. Crandall, Ashley N. Egan, Matthew S. Haynsen, Dennis X. Zhu, Gouri Mahadwar, Mohammad Vatanparast, Roy Z. Moger-Reischer

Publikováno v: Haynsen, M S, Vatanparast, M, Mahadwar, G, Zhu, D, Moger-reischer, R Z, Doyle, J J, Crandall, K A & Egan, A N 2018, ' De novo transcriptome assembly of Pueraria montana var . lobata and Neustanthus phaseoloides for the development of eSSR and SNP markers : narrowing the US origin(s) of the invasive kudzu ', BMC Genomics, vol. 19, no. 1, 439 . https://doi.org/10.1186/s12864-018-4798-3
BMC Genomics, Vol 19, Iss 1, Pp 1-17 (2018)

Background Kudzu, Pueraria montana var. lobata, is a woody vine native to Southeast Asia that has been introduced globally for cattle forage and erosion control. The vine is highly invasive in its introduced areas, including the southeastern US. Mode

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54147399c50e84c7fd733c8096ed859b
https://curis.ku.dk/ws/files/222610981/De_novo_transcriptome_assembly_of_Pueraria_montana_var._lobata_and_Neustanthus_phaseoloides_for_the_development_of_eSSR_and_SNP_markers.pdf