Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Dennis Wolford"'
Autor:
Christine Fandozzi, Deborah Panebianco, Luzelena Caro, Dennis Wolford, Zifang Guo, Iain P. Fraser, Dennis Swearingen, Vanessa Levine, Hwa-Ping Feng, Thomayant Prueksaritanont, Joan R. Butterton, Marian Iwamoto, Wendy W. Yeh
Publikováno v:
Clinical Drug Investigation. 41:133-147
Many people infected with hepatitis C virus have comorbidities, including hypercholesterolemia, that are treated with statins. In this study, we evaluated the drug–drug interaction potential of the hepatitis C virus inhibitors elbasvir (EBR) and gr
Autor:
Luzelena, Caro, Thomayant, Prueksaritanont, Christine M, Fandozzi, Hwa-Ping, Feng, Zifang, Guo, Dennis, Wolford, Deborah, Panebianco, Iain P, Fraser, Vanessa, Levine, Dennis, Swearingen, Joan R, Butterton, Marian, Iwamoto, Wendy W, Yeh
Publikováno v:
Clinical drug investigation. 41(2)
Many people infected with hepatitis C virus have comorbidities, including hypercholesterolemia, that are treated with statins. In this study, we evaluated the drug-drug interaction potential of the hepatitis C virus inhibitors elbasvir (EBR) and graz
Autor:
Patricia Jumes, Lynn Webster, Zifang Guo, Wendy W. Yeh, Luzelena Caro, Pavan Vaddady, Monika Martinho, Dennis Wolford, Deborah Panebianco, Marian Iwamoto, Hwa-Ping Feng, Christina Reitmann, Iain Fraser, Joan R. Butterton, Robert Valesky, William L. Marshall, Fang Liu
Publikováno v:
Clinical and Translational Science. 11:553-561
We conducted two phase I trials to evaluate the pharmacokinetic interactions between elbasvir (EBR), grazoprevir (GZR), and methadone (MK-8742-P010 and MK-5172-P030) in non-hepatitis C virus (HCV)-infected participants on methadone maintenance therap
Autor:
William L. Marshall, Luzelena Caro, Jocelyn Gilmartin, Dennis Wolford, Zifang Guo, April M. Barbour, Monika Martinho, Christina Reitmann, Lynn Webster, Pavan Vaddady, Deborah Panebianco, Iain Fraser, Wendy W. Yeh, Marian Iwamoto, Fang Liu, Patricia Jumes, Robert Valesky, Joan R. Butterton, Hwa-Ping Feng
Publikováno v:
Clinical and Translational Science. 11:562-572
The aims of these phase I trials were to evaluate the pharmacokinetic interaction between elbasvir (EBR) or grazoprevir (GZR) and buprenorphine/naloxone (BUP/NAL). Trial 1 was a single-dose trial in healthy participants. Trial 2 was a multiple-dose t
Autor:
Zifang Guo, Christine Fandozzi, Luzelena Caro, Matthew L. Rizk, Robert Valesky, Deborah Panebianco, Daniel P. Dreyer, Monika Martinho, Wendy W. Yeh, Marian Iwamoto, Hwa-Ping Feng, Dennis Wolford
Publikováno v:
Clinical pharmacology in drug developmentReferences. 8(7)
Treatment of individuals coinfected with human immunodeficiency virus (HIV) and hepatitis C virus (HCV) requires careful consideration of potential drug-drug interactions. The pharmacokinetic interaction of the HCV fixed-dose combination treatment of
Autor:
Hwa-Ping, Feng, Zifang, Guo, Luzelena, Caro, William L, Marshall, Fang, Liu, Deborah, Panebianco, Pavan, Vaddady, Christina, Reitmann, Patricia, Jumes, Dennis, Wolford, Iain, Fraser, Robert, Valesky, Monika, Martinho, Joan R, Butterton, Marian, Iwamoto, Lynn, Webster, Wendy W, Yeh
Publikováno v:
Clinical and Translational Science
We conducted two phase I trials to evaluate the pharmacokinetic interactions between elbasvir (EBR), grazoprevir (GZR), and methadone (MK‐8742‐P010 and MK‐5172‐P030) in non‐hepatitis C virus (HCV)‐infected participants on methadone mainte
Autor:
Christina Reitmann, Dennis Wolford, Kenneth C. Lasseter, David E. Gutstein, Rebecca E Wrishko, William D. Hanley, Joanna Udo de Haes, K Chris Min, Thomas Marbury
Publikováno v:
Int. Journal of Clinical Pharmacology and Therapeutics.
AIMS Sugammadex rapidly reverses moderate and deep rocuronium- or vecuronium-induced neuromuscular blockade at doses of 4 mg/kg and 2 mg/kg, respectively. Sugammadex is renally eliminated. This study evaluated the pharmacokinetics of sugammadex in su
Autor:
Luzelena Caro, Dennis Wolford, Zifang Guo, Christine Fandozzi, Jennifer Talaty, Marian Iwamoto, Wendy W. Yeh, Deborah Panebianco, Hwa-Ping Feng, Joan R. Butterton
Publikováno v:
Journal of clinical pharmacology. 58(5)
Elbasvir (EBR)/grazoprevir (GZR) may be coadministered with immunosuppressant drugs in posttransplant people who are infected with hepatitis C virus. The aim of the present study was to assess the safety and pharmacokinetic interactions between EBR a
Autor:
Antonios O. Aliprantis, Laura M. Sterling, Luzelena Caro, Dennis Wolford, Radha Railkar, Kalpit A. Vora, Andrew W. Lee, Eseng Lai, Dong Geng, Hua Ma, Brian M. Maas
Publikováno v:
Open Forum Infectious Diseases
Background Respiratory syncytial virus (RSV) is the most common cause of lower respiratory tract infection and hospitalization in infants. Prophylaxis for RSV infection is only recommended for the highest risk infants, leaving the majority of infants
Autor:
Kristine Cerchio, Jacqueline B. McCrea, Dennis Wolford, Julia Boyle, Christopher R. Lines, Cynthia Gargano, Corinne E. Cummings
Publikováno v:
Human psychopharmacology. 24(1)
Objective To evaluate the next-day residual effects of the novel hypnotic, gaboxadol, following bedtime dosing in healthy elderly subjects. Methods Healthy women (N = 15) and men (N = 10) aged 65–79 years received a single bedtime (22:00 h) dose of