Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Dennis Wegener"'
Autor:
Olaf Witt, Matthias Fischer, Andreas von Deimling, Scott M. Ulrich, Frank Westermann, Annette Kopp-Schneider, Barbara Hero, Jan-Peter Linke, Diana Pickert, Dennis Wegener, Hedwig E. Deubzer, Ina Oehme
Supplementary Data from Histone Deacetylase 8 in Neuroblastoma Tumorigenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1646f5d85a6f1b3ed1dc07be4d3e42c
https://doi.org/10.1158/1078-0432.22439535
https://doi.org/10.1158/1078-0432.22439535
Autor:
Olaf Witt, Matthias Fischer, Andreas von Deimling, Scott M. Ulrich, Frank Westermann, Annette Kopp-Schneider, Barbara Hero, Jan-Peter Linke, Diana Pickert, Dennis Wegener, Hedwig E. Deubzer, Ina Oehme
Purpose: The effects of pan–histone deacetylase (HDAC) inhibitors on cancer cells have shown that HDACs are involved in fundamental tumor biological processes such as cell cycle control, differentiation, and apoptosis. However, because of the unsel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29877de54320589c01f6599784972bc4
https://doi.org/10.1158/1078-0432.c.6516984.v1
https://doi.org/10.1158/1078-0432.c.6516984.v1
Autor:
W. David Church, Dennis Wegener, Tim J. Wigle, Arne Brendes, Kevin Wayne Kuntz, Demet Aybar, Paul Chang, Melissa Vasbinder, Claudia Beck, Martin Prahm, Kerren Kalai Swinger, Laurie B. Schenkel, Christina R. Majer
Publikováno v:
Slas Discovery
Mono(ADP-ribosylation) (MARylation) and poly(ADP-ribosylation) (PARylation) are posttranslational modifications found on multiple amino acids. There are 12 enzymatically active mono(ADP-ribose) polymerase (monoPARP) enzymes and 4 enzymatically active
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4686c9e26862cf3e83c8463a96216730
https://doi.org/10.1177/2472555219883623
https://doi.org/10.1177/2472555219883623
Autor:
Daniel Riester, Sukhdeep Singh, Gregor Schlingloff, G. Alexander Groß, Dennis Wegener, Andreas Schwienhorst, Hanns Wurziger, Andreas Schober
Publikováno v:
Engineering in Life Sciences. 13:344-351
Modern drug development in preclinical pharmaceutics is based on two fundamental processes: library synthesis and screening. Usually, synthesis and screening are separated processes that need a compound storage facility as an interface. Unfortunately
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0e089b017c4a2e165733e2b1a6cae2fa
https://doi.org/10.1002/elsc.201200090
https://doi.org/10.1002/elsc.201200090
Publikováno v:
BIBM Workshops
Medicine is undergoing a revolution that is even transforming the nature of health care from reactive to proactive. To serve these new and diverse needs, bioinformatics and data mining are teaming up to generate tools and procedures for prediction of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffaba67b366d004a2de360e9b54ca343
https://doi.org/10.1007/s13721-013-0022-1
https://doi.org/10.1007/s13721-013-0022-1
Publikováno v:
International Journal of Semantic Computing. :315-327
Today's search interfaces typically offer keyword searches and facets for the retrieval of cultural heritage multimedia objects. Facets, however, are usually based on a static set of metadata fields. This set is often called an indexing profile. Grap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b00d604eef59c6f3cc42adee46d5bd5
https://doi.org/10.1142/s1793351x12400107
https://doi.org/10.1142/s1793351x12400107
Autor:
Dennis Wegener, Barbara Hero, Annette Kopp-Schneider, Frank Westermann, Andreas von Deimling, Olaf Witt, Matthias Fischer, Ina Oehme, Diana Pickert, Jan Peter Linke, Hedwig E. Deubzer, Scott M. Ulrich
Publikováno v:
Clinical Cancer Research. 15:91-99
Purpose: The effects of pan–histone deacetylase (HDAC) inhibitors on cancer cells have shown that HDACs are involved in fundamental tumor biological processes such as cell cycle control, differentiation, and apoptosis. However, because of the unsel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08e4b3d775339317e4bb6676ef927b29
https://doi.org/10.1158/1078-0432.ccr-08-0684
https://doi.org/10.1158/1078-0432.ccr-08-0684
Autor:
Dennis Wegener, Valentin Kravtsov, Thomas Niessen, Werner Dubitzky, M. Rohm, J. Franke, Vlado Stankovski, Assaf Schuster, Martin T. Swain, M. May, Jernej Trnkoczy
Publikováno v:
IEEE Internet Computing. 12:69-76
As modern data mining applications increase in complexity, so too do their demands for resources. Grid computing is one of several emerging networked computing paradigms promising to meet the requirements of heterogeneous, large-scale, and distribute
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ef97fff67b7648d041d4aee875ea328
https://doi.org/10.1109/mic.2008.122
https://doi.org/10.1109/mic.2008.122
Autor:
Dennis Wegener, Jörg Kindermann, Martin T. Swain, Thomas Niessen, Werner Dubitzky, Vlado Stankovski, Valentin Kravtsov
Publikováno v:
Future Generation Computer Systems. 24:259-279
The DataMiningGrid system has been designed to meet the requirements of modern and distributed data mining scenarios. Based on the Globus Toolkit and other open technology and standards, the DataMiningGrid system provides tools and services facilitat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b80794bd97c96808ec2d4c06c38b0fe
https://doi.org/10.1016/j.future.2007.05.004
https://doi.org/10.1016/j.future.2007.05.004
Autor:
Christian Hildmann, Tine Kragh Nielsen, Dennis Wegener, Daniel Riester, Andreas Schwienhorst, Ralf Ficner
Publikováno v:
Acta Crystallographica Section F Structural Biology and Crystallization Communications. 63:270-273
Histone deacetylases (HDACs) have emerged as attractive targets in anticancer drug development. To date, a number of HDAC inhibitors have been developed and most of them are hydroxamic acid derivatives, typified by suberoylanilide hydroxamic acid (SA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46c632fdd5f514dea80ff36430f71833
https://doi.org/10.1107/s1744309107012377
https://doi.org/10.1107/s1744309107012377