Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Dennis W. Stacey"'
Autor:
Dennis W. Stacey
Publikováno v:
Genes & Cancer. 1:1189-1199
Our understanding of cell cycle control has been based largely upon studies of synchronized cultures, often focused upon the early stages of the cell cycle following stimulation of quiescent cultures. These studies showed that cyclin D1 and p27Kip1 (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::30f9877ec853fdfe2f8b93244a64efd8
https://doi.org/10.1177/1947601911403475
https://doi.org/10.1177/1947601911403475
Autor:
Masahiro Hitomi, Dennis W. Stacey
Publikováno v:
Cytometry Part A. :270-278
When cell cycle studies are performed following cell cycle synchronization, it is possible that critical properties of an actively cycling cell will be overlooked. For this reason past studies have not revealed critical aspects of cell cycle control;
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbd207d54f95f6916a947bf8995fbbd1
https://doi.org/10.1002/cyto.a.20511
https://doi.org/10.1002/cyto.a.20511
Publikováno v:
Cell Cycle. 5:2281-2289
When quiescent cells are stimulated to reenter the cell cycle, growth factors are required only until the restriction point in G(1) phase. After this point the cell no longer requires growth factors, proliferative signaling molecules, or even protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e0315ccbc96b4b1773f81527df87766
https://doi.org/10.4161/cc.5.19.3318
https://doi.org/10.4161/cc.5.19.3318
Publikováno v:
Oncogene. 24:1032-1042
Cyclin D1 is critical for entry into, continuation of, and exit from the cell division cycle. Mitogen stimulation of quiescent cells induces cyclin D1 expression in a transcription-dependent manner. In actively cycling cells, on the other hand, fluct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3abfc8405870cb254450a2e716966982
https://doi.org/10.1038/sj.onc.1208299
https://doi.org/10.1038/sj.onc.1208299
Autor:
Gaurisankar Sa, Dennis W. Stacey
Publikováno v:
Experimental Cell Research. 300:427-439
The cyclin inhibitory protein p27Kip1 (p27) plays a vital role in regulating cell proliferation in response to the extracellular growth environment. Active proliferation requires the suppression of p27 levels throughout the cell cycle. Late in the ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5eb644a1d7a675317656ed4815bd9ab6
https://doi.org/10.1016/j.yexcr.2004.07.032
https://doi.org/10.1016/j.yexcr.2004.07.032
Autor:
Dennis W. Stacey
Publikováno v:
Current Opinion in Cell Biology. 15:158-163
Much of our current understanding of the cell cycle involves analyses of its induction in quiescent cells. To better understand the control of cell cycle propagation and termination, studies have been performed in actively cycling cultures using time
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea965a68f4cf999f0e3000542518dd8b
https://doi.org/10.1016/s0955-0674(03)00008-5
https://doi.org/10.1016/s0955-0674(03)00008-5
Autor:
Guan Chen Gc, Jyoti A. Harwalkar, Masahiro Hitomi, Dennis W. Stacey, Andrew W. Stacey, Gaurisankar Sa
Publikováno v:
Cell Cycle. 1:46-54
The control of cell cycle progression has been studied in asynchronous cultures using image analysis and time lapse techniques. This approach allows determination of the cycle phase and signaling properties of individual cells, and avoids the need fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::207f0e0052d4664e985f80dd2b7a3631
https://doi.org/10.4161/cc.1.1.100
https://doi.org/10.4161/cc.1.1.100
Publikováno v:
Oncogene. 18:7149-7160
Topoisomerase II alpha (topo II alpha) is a major target of antitumor treatments. In an effort to determine why this protein might be a better target in tumor cells than in normal cells, we attempted to determine if the altered proliferative signalin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b2771515e7fc910c03748a020890fe0
https://doi.org/10.1038/sj.onc.1203149
https://doi.org/10.1038/sj.onc.1203149
Publikováno v:
Oncogene. 18:4254-4261
Levels of Pur alpha, a protein implicated in control of both DNA replication and gene transcription, fluctuate during the cell cycle, being lowest in early S phase and highest just after mitosis. Here we have employed a new video time-lapse technique
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f49560f7fd60396a0602870f0c41679a
https://doi.org/10.1038/sj.onc.1202795
https://doi.org/10.1038/sj.onc.1202795
Autor:
Tom Slabe, Dennis W. Stacey, Charles L. Hoppel, Mladen Golubic, Margaret Roudebush, Vidya Sundaram
Publikováno v:
Experimental Cell Research. 236:161-172
Mutations in neurofibromatosis type 1 target the gene coding for neurofibromin. While neurofibromin is able to accelerate the rate of GTP hydrolysis by cellular Ras proteins, its biological function is not well understood. To gain information regardi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58300443bd369668a998e6d5caf15092
https://doi.org/10.1006/excr.1997.3712
https://doi.org/10.1006/excr.1997.3712