Zobrazeno 1 - 10
of 98
pro vyhledávání: '"Dennis W. P. M. Löwik"'
Publikováno v:
Pharmaceutics, Vol 13, Iss 9, p 1391 (2021)
Cell-penetrating peptides (CPPs), also known as protein transduction domains, are a class of diverse amino acid sequences with the ability to cross cellular membranes. CPPs can deliver several bioactive cargos, including proteins, peptides, nucleic a
Externí odkaz:
https://doaj.org/article/88884de59fd744869346a9302d917b37
Autor:
Daan Sondag, Stijn Verhoeven, Dennis W. P. M. Löwik, Mark van Geffen, Cornelis van't Veer, Waander L. van Heerde, Thomas J. Boltje, Floris P. J. T. Rutjes
Publikováno v:
Chemistry – A European Journal. 29
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba2091f746a804415ca9c5110280d163
https://doi.org/10.1002/chem.202381862
https://doi.org/10.1002/chem.202381862
Autor:
Yvonne H. W. Derks, Melline G. M. Schilham, Mark Rijpkema, Esther M. M. Smeets, Helene I. V. Amatdjais-Groenen, Annemarie Kip, Sanne A. M. van Lith, Jill van de Kamp, J. P. Michiel Sedelaar, Diederik M. Somford, Michiel Simons, Peter Laverman, Martin Gotthardt, Dennis W. P. M. Löwik, Sandra Heskamp, Susanne Lütje
Publikováno v:
European Journal of Nuclear Medicine and Molecular Imaging, 50, 9, pp. 2872-2884
Purpose Incomplete resection of prostate cancer (PCa) results in increased risk of disease recurrence. Combined fluorescence-guided surgery with tumor-targeted photodynamic therapy (tPDT) may help to achieve complete tumor eradication. We developed a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7ecbc1450682f82ccc894d8216083a3
https://repository.ubn.ru.nl/handle/2066/294532
https://repository.ubn.ru.nl/handle/2066/294532
Autor:
Daan Sondag, Stijn Verhoeven, Dennis W. P. M. Löwik, Mark van Geffen, Cornelis van't Veer, Waander L. van Heerde, Thomas J. Boltje, Floris P. J. T. Rutjes
Publikováno v:
Chemistry : a European Journal, 29
Chemistry : a European Journal, 29, 18
Chemistry : a European Journal, 29, 18
Contains fulltext : 291544.pdf (Publisher’s version ) (Open Access) The blood coagulation cascade is a complex physiological process involving the action of multiple coupled enzymes, cofactors, and substrates, ultimately leading to clot formation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99e73a65dae18c7cc0b6275a0079c95d
http://hdl.handle.net/2066/291544
http://hdl.handle.net/2066/291544
Autor:
Daan Sondag, Luuk Maartense, Heleen de Jong, Frank F. J. de Kleijne, Kimberly M. Bonger, Dennis W. P. M. Löwik, Thomas J. Boltje, Jan Dommerholt, Paul B. White, Daniel Blanco‐Ania, Floris P. J. T. Rutjes
Publikováno v:
Chemistry : a European Journal, 29, 6, pp. 1-9
Chemistry : a European Journal, 29, 1-9
Chemistry : a European Journal, 29, 1-9
The click reaction between a functionalized trans-cyclooctene (TCO) and a tetrazine (Tz) is a compelling method for bioorthogonal conjugation in combination with payload releasing capabilities. However, the synthesis of difunctionalized TCOs remains
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c51fe2d06ff1284e8ed85a753644bbf6
https://pubmed.ncbi.nlm.nih.gov/36478614
https://pubmed.ncbi.nlm.nih.gov/36478614
Publikováno v:
International Journal of Peptide Research and Therapeutics, 28, 1-11
International Journal of Peptide Research and Therapeutics, 28, 5, pp. 1-11
International Journal of Peptide Research and Therapeutics, 28, 5, pp. 1-11
Contains fulltext : 252813.pdf (Publisher’s version ) (Closed access)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f63d22382371b31c9cc18108a2b0c0f5
https://doi.org/10.1007/s10989-022-10446-6
https://doi.org/10.1007/s10989-022-10446-6
Autor:
Daan, Sondag, Jona, Merx, Emiel, Rossing, Thomas J, Boltje, Dennis W P M, Löwik, Frank H T, Nelissen, Mark, van Geffen, Cornelis, van 't Veer, Waander L, van Heerde, Floris P J T, Rutjes
Publikováno v:
Chembiochem : a European journal of chemical biology. 23(15)
Since the outbreak of SARS-CoV-2 in December 2019 millions of infections have been reported globally. The viral chymotrypsin-like main protease (M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e9c68eb205b3d6e8b86a21d346f0fc46
https://pubmed.ncbi.nlm.nih.gov/35649961
https://pubmed.ncbi.nlm.nih.gov/35649961
Publikováno v:
Amino Acids
Amino Acids, 52, 1161-1168
Amino Acids, 52, pp. 1161-1168
Amino Acids, 52, 1161-1168
Amino Acids, 52, pp. 1161-1168
Three cell-penetrating peptides (CPPs), Tat, Pep-3 and penetratin, were split into two parts and each fragment was terminated with a cysteine residue, to allow disulfide bridge formation, as well as a fluorescent label, for visualization and quantita
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35a3e9f9ff24d773896afac1270bae94
https://doi.org/10.1007/s00726-020-02880-x
https://doi.org/10.1007/s00726-020-02880-x
Publikováno v:
RSC Chemical Biology
An important hurdle for the intracellular delivery of large cargo is the cellular membrane, which protects the cell from exogenous substances. Cell-penetrating peptides (CPPs) can cross this barrier but their use as drug delivery vehicles is hampered
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f46fe6699b6f89316d1ad225392bfb4
https://doi.org/10.1039/d0cb00114g
https://doi.org/10.1039/d0cb00114g
Publikováno v:
ACS applied bio materials. 2(7)
Hydrogels are water-saturated polymer networks and extensively used in drug delivery, tissue repair engineering, and cell cultures. For encapsulation of drugs or cells, the possibility to form hydrogels
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::49d27f863ef699c8df0ee45fe19dbcab
https://pubmed.ncbi.nlm.nih.gov/35030820
https://pubmed.ncbi.nlm.nih.gov/35030820