Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Dennis W. McGraw"'
Autor:
Ashok Kumar, Huan Liu, Francis X. McCormack, Masaki Hirose, Dennis W. McGraw, Nishant Gupta, Yoshikazu Inoue, Kathryn A. Wikenheiser-Brokamp, Andrew R. Osterburg, Jennifer Flury, Michael T. Borchers, Abdellatif Tazi, Zulma Swank
Pulmonary Langerhans cell histiocytosis (PLCH) is a rare smoking-related lung disease characterized by dendritic cell (DC) accumulation, bronchiolocentric nodule formation, and cystic lung remodeling. Approximately 50% of patients with PLCH harbor so
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbdbbdb6ae512ccb758534c68e6b8f4d
https://europepmc.org/articles/PMC7101136/
https://europepmc.org/articles/PMC7101136/
Autor:
Larry Sallans, Melinda Butsch Kovacic, Stephen F. Macha, Krzysztof J. Reszka, Dennis W. McGraw, Bradley E. Britigan, Kari M. Brown
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 336:440-449
β(2)-agonists are the most effective bronchodilators for the rapid relief of asthma symptoms, but for unclear reasons, their effectiveness may be decreased during severe exacerbations. Because peroxidase activity and nitrogen oxides are increased in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbed852abdce73766ec9aca0bcb38189
https://doi.org/10.1124/jpet.110.170027
https://doi.org/10.1124/jpet.110.170027
Autor:
Snezana Petrovic, Li V. Yang, Dennis W. McGraw, Lois J. Arend, Brian C. Tiegs, Xuming Sun, Raymond B. Penn
Publikováno v:
Journal of the American Society of Nephrology. 21:1745-1755
Proton receptors are G protein-coupled receptors that accept protons as ligands and function as pH sensors. One of the proton receptors, GPR4, is relatively abundant in the kidney, but its potential role in acid-base homeostasis is unknown. In this s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05aee985f685b7a544acee3e970ee4cc
https://doi.org/10.1681/asn.2009050477
https://doi.org/10.1681/asn.2009050477
Autor:
Marc E. Rothenberg, Clare B. Glinka, Jean M. Elwing, Dennis W. McGraw, Wayne C. H. Wang, Kevin M. Fogel, Kathryn A. Mihlbachler, Stephen B. Liggett
Publikováno v:
Journal of Clinical Investigation. 117:1391-1398
Receptor-mediated airway smooth muscle (ASM) contraction via G(alphaq), and relaxation via G(alphas), underlie the bronchospastic features of asthma and its treatment. Asthma models show increased ASM G(alphai) expression, considered the basis for th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85ec27084baf580e5ca528235bb256d6
https://doi.org/10.1172/jci30489
https://doi.org/10.1172/jci30489
Autor:
Dennis W. McGraw, Yoshikazu Inoue, Yves Sabbagh, Jason D. Gardner, Kathryn A. Wikenheiser-Brokamp, Marko Jakopović, Francis X. McCormack, Atsushi Saito, Yasuaki Uehara, Lori B. Pitstick, Susan C. Schiavi, Kathleen LaSance, Nikolaos M. Nikolaidis, Jason C. Woods, Goksel Altinisik, James P. Bridges, Hassane Amlal
Publikováno v:
Science Translational Medicine. 7
Pulmonary alveolar microlithiasis (PAM) is a rare, autosomal recessive lung disorder associated with progressive accumulation of calcium phosphate microliths. Inactivating mutations in SLC34A2, which encodes the NPT2b sodium-dependent phosphate cotra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da1c723daf6c246ecf9ec63ecbfe00f9
https://doi.org/10.1126/scitranslmed.aac8577
https://doi.org/10.1126/scitranslmed.aac8577
Autor:
Khalid F. Almoosa, Mary Rose Schwarb, Kathryn A. Mihlbachler, Kersten M. Small, Dennis W. McGraw, Stephen B. Liggett, Fahema F. Rahman
Publikováno v:
Journal of Clinical Investigation. 116:1400-1409
Multiple and paradoxical effects of airway smooth muscle (ASM) 7-transmembrane-spanning receptors activated during asthma, or by treatment with bronchodilators such as beta(2)-adrenergic receptor (beta(2)AR) agonists, indicate extensive receptor cros
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e5f6ee145f23338c5472650b5552cbd
https://doi.org/10.1172/jci25840
https://doi.org/10.1172/jci25840
Autor:
Guoli Chen, E. Kevin Heist, Ilona Bodi, Evangelia G. Kranias, John N. Lorenz, Jo El J. Schultz, Harvey S. Hahn, Yehia Marreez, Nirmala Mavila, Doug Weiser, Anand Pathak, Anna A. DePaoli-Roach, Leena Jha, Federica del Monte, Faisal M. Syed, J. Luis Guerrero, Roger J. Hajjar, Jiang Qian, Andrew N. Carr, Wen Zhao, Dennis W. McGraw
Publikováno v:
Circulation Research. 96:756-766
Abnormal calcium cycling, characteristic of experimental and human heart failure, is associated with impaired sarcoplasmic reticulum calcium uptake activity. This reflects decreases in the cAMP-pathway signaling and increases in type 1 phosphatase ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d90bfd3f4ae9a57cb4c7dde59379e407
https://doi.org/10.1161/01.res.0000161256.85833.fa
https://doi.org/10.1161/01.res.0000161256.85833.fa
Autor:
Thomas J. Mariani, Kenneth C. Malcolm, Nir Friedman, Yi Zhang, Daniel R. Prows, Alvin M. Malkinson, Gary L. Johnson, Aviv Regev, Yan Xu, Laura Zerbe, Jay W. Tichelaar, Wilbur A. Franklin, Robert S. Stearman, Susan E. Wert, Stephan W. Glasser, Yingze Zhang, G. S. Worthen, Stephanie Nonas, Craig R. Tomlinson, Timothy E. Weaver, George D. Leikauf, David G. Peters, Wendy K. Steagall, Joel Moss, Jeffrey A. Whitsett, Edwin K. Silverman, Kamon Kawkitinarong, Gustavo Pacheco-Rodriguez, Susan A. McDowell, Lisa M. Henning, Mark W. Duncan, Dennis W. McGraw, Lisa M. Case, Connie Glasgow, Mario Medvedovic, Michael B. Fessler, David A. Schwartz, Donald N. Cook, Stephen B. Liggett, Cindy J. Bachurski, William D. Hardie, Robert C. Elston, Thomas R. Korfhagen, Angelo Taveira-DaSilva, Denise Crooks, Robert L. Keith, Lyle J. Palmer, Joe G.N. Garcia, Kathleen C. Barnes, Lori Dwyer-Nield, Katsuya Tsukada, Susan Redline, Lawrence M. Nogee, Mark W. Geraci, Scott C. Wesselkamper, Naftali Kaminski, Paul A. Bunn, Maureen A. Sartor, Augustine M.K. Choi
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 31:S1-S81
Jeffrey A. Whitsett, Cindy J. Bachurski, Kathleen C. Barnes, Paul A. Bunn, Jr., Lisa M. Case, Donald N. Cook, Denise Crooks, Mark W. Duncan, Lori Dwyer-Nield, Robert C. Elston, Michael B. Fessler, Wilbur A. Franklin, Nir Friedman, Joe G. N. Garcia, M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dfc5e19f348e6cf940ec9c5fd06204b4
https://doi.org/10.1165/rcmb.2004-0071su
https://doi.org/10.1165/rcmb.2004-0071su
Publikováno v:
Journal of Clinical Investigation. 112:619-626
beta-adrenergic receptors (betaARs) relax airway smooth muscle and bronchodilate, but chronic beta-agonist treatment in asthma causes increased sensitivity to airway constriction (hyperreactivity) and is associated with exacerbations. This paradox wa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e38768d227e9359e0fb0ad3d4eb49a72
https://doi.org/10.1172/jci18193
https://doi.org/10.1172/jci18193
Publikováno v:
American journal of critical care : an official publication, American Association of Critical-Care Nurses. 23(2)
Lemierre syndrome is a rare and life-threatening illness. Often referred to as “the forgotten disease,” its incidence is reported to be as low as 1 in a million. The microorganism responsible for Lemierre syndrome is typically Fusobacterium necro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac19fa73f20426b096fb5a45faed770a
https://pubmed.ncbi.nlm.nih.gov/24585168
https://pubmed.ncbi.nlm.nih.gov/24585168