Zobrazeno 1 - 10
of 189
pro vyhledávání: '"Dennis W, Metzger"'
Autor:
Rae D. Record Ritchie, PhD, Sharon L. Salmon, BSc, Michael C. Hiles, PhD, Dennis W. Metzger, PhD
Publikováno v:
Surgery Open Science, Vol 10, Iss , Pp 83-90 (2022)
Background: Clinically useful biomaterials are derived from xenogeneic extracellular matrices, but extensive processes often used to remove all residual DNA are detrimental to their proper biological function. We hypothesized that deliberate and repe
Externí odkaz:
https://doaj.org/article/8e28ccf4173b4955ba0438c11f1faa4f
Autor:
Tarani Kanta Barman, Amit K. Singh, Jesse L. Bonin, Tanvir Noor Nafiz, Sharon L. Salmon, Dennis W. Metzger
Publikováno v:
JCI Insight, Vol 7, Iss 11 (2022)
Secondary infections are frequent complications of viral respiratory infections, but the potential consequence of SARS-CoV-2 coinfection with common pulmonary pathogens is poorly understood. We report that coinfection of human ACE2–transgenic mice
Externí odkaz:
https://doaj.org/article/03ba45e91b9c4372a8c1ea9c4ab5432f
Topical application of nebulized human IgG, IgA and IgAM in the lungs of rats and non-human primates
Autor:
Cédric Vonarburg, Marius Loetscher, Martin O. Spycher, Alain Kropf, Marlies Illi, Sharon Salmon, Sean Roberts, Karin Steinfuehrer, Ian Campbell, Sandra Koernig, Joseph Bain, Monika Edler, Ulrich Baumann, Sylvia Miescher, Dennis W. Metzger, Alexander Schaub, Fabian Käsermann, Adrian W. Zuercher
Publikováno v:
Respiratory Research, Vol 20, Iss 1, Pp 1-16 (2019)
Abstract Background Recurrent and persistent infections are known to affect airways of patients with Primary Immunodeficiency despite appropriate replacement immunoglobulin serum levels. Interestingly, patients with Chronic Obstructive Pulmonary Dise
Externí odkaz:
https://doaj.org/article/14ff40a2a8dd402c98faa7221f7dd197
Autor:
Tarani Kanta Barman, Rachael Racine, Jesse L Bonin, Danielle Califano, Sharon L Salmon, Dennis W Metzger
Publikováno v:
PLoS Pathogens, Vol 17, Iss 3, p e1009405 (2021)
Bacterial co-infections represent a major clinical complication of influenza. Host-derived interferon (IFN) increases susceptibility to bacterial infections following influenza, but the relative roles of type-I versus type-II IFN remain poorly unders
Externí odkaz:
https://doaj.org/article/330e733cd7554e13bdb11b1f3afaac28
Autor:
Tarani Kanta Barman, Dennis W. Metzger
Publikováno v:
Viruses, Vol 13, Iss 12, p 2362 (2021)
Disease tolerance has emerged as an alternative way, in addition to host resistance, to survive viral-bacterial co-infections. Disease tolerance plays an important role not in reducing pathogen burden, but in maintaining tissue integrity and controll
Externí odkaz:
https://doaj.org/article/3e8e950803d0486ba8e04cd6d779552a
Autor:
Sean Roberts, Sharon L. Salmon, Donald J. Steiner, Clare M. Williams, Dennis W. Metzger, Yoichi Furuya
Publikováno v:
mBio, Vol 10, Iss 4 (2019)
ABSTRACT Fatal outcomes following influenza infection are often associated with secondary bacterial infections. Allergic airway disease (AAD) is known to influence severe complications from respiratory infections, and yet the mechanistic effect of AA
Externí odkaz:
https://doaj.org/article/9dd5786ecf724d57874c90af930d89a7
Publikováno v:
The Journal of Immunology. 207:1371-1376
Inflammatory cytokine storm is a known cause for acute respiratory distress syndrome. In this study, we have investigated the role of IFN-γ in lethal lung inflammation using a mouse model of postinfluenza methicillin-resistant Staphylococcus aureus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f3cbff93f685da467d6dc0703ba20b46
https://doi.org/10.4049/jimmunol.2100328
https://doi.org/10.4049/jimmunol.2100328
Autor:
Sean Roberts, Clare M. Williams, Sharon L. Salmon, Jesse L. Bonin, Dennis W. Metzger, Yoichi Furuya
Publikováno v:
Vaccines, Vol 7, Iss 4, p 146 (2019)
Secondary bacterial pneumonia is responsible for significant morbidity and mortality during seasonal and pandemic influenza. Due to the unpredictability of influenza A virus evolution and the time-consuming process of manufacturing strain-specific in
Externí odkaz:
https://doaj.org/article/cc68d25350c148e0acb6948fa6b059b1
Publikováno v:
Journal of Tissue Viability. 29:42-47
Background The SIS Wound Matrix (SISWM) has been shown to improve healing of chronic ulcers over standard of care. In this study, we tested the hypothesis that chronic venous ulcers responsive to treatment with SISWM would more closely mimic an acute
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed13bdc4f17412edcccba15386b9a4b5
https://doi.org/10.1016/j.jtv.2019.12.003
https://doi.org/10.1016/j.jtv.2019.12.003
Autor:
Tarani Kanta Barman, Victor C. Huber, Jesse L. Bonin, Danielle Califano, Sharon L. Salmon, Andrew N. J. McKenzie, Dennis W. Metzger
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(8)
SignificanceThe regulation of functional immune cell plasticity is poorly understood. Host environmental cues are critical, but the possible influence of pathogen-derived virulence factors has not been described. We have used reverse-engineered influ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f92e27ae84e65a44a8347f88ae45d79
https://pubmed.ncbi.nlm.nih.gov/35169077
https://pubmed.ncbi.nlm.nih.gov/35169077