Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Dennis Vitkup"'
Autor:
Anna S. Dickson, Tekle Pauzaite, Esther Arnaiz, Brian M. Ortmann, James A. West, Norbert Volkmar, Anthony W. Martinelli, Zhaoqi Li, Niek Wit, Dennis Vitkup, Arthur Kaser, Paul J. Lehner, James A. Nathan
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Cholesterol biosynthesis is a highly regulated, oxygen-dependent pathway, vital for cell membrane integrity and growth. In fungi, the dependency on oxygen for sterol production has resulted in a shared transcriptional response, resembling pr
Externí odkaz:
https://doaj.org/article/c87d491caba847fcaeae18fb670de9f1
Autor:
Anna S. Dickson, Tekle Pauzaite, Esther Arnaiz, Brian M. Ortmann, James A. West, Norbert Volkmar, Anthony W. Martinelli, Zhaoqi Li, Niek Wit, Dennis Vitkup, Arthur Kaser, Paul J. Lehner, James A. Nathan
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/1e8df5e5952f458ba4cea0c1b5668fea
Autor:
Anna S. Dickson, Tekle Pauzaite, Esther Arnaiz, Brian M. Ortmann, James A. West, Norbert Volkmar, Anthony W. Martinelli, Zhaoqi Li, Niek Wit, Dennis Vitkup, Arthur Kaser, Paul J. Lehner, James A. Nathan
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/2599fb5071604775b7eff4fa0c444bd5
Autor:
Eugenia Lyashenko, Mario Niepel, Purushottam D Dixit, Sang Kyun Lim, Peter K Sorger, Dennis Vitkup
Publikováno v:
eLife, Vol 9 (2020)
Detecting relative rather than absolute changes in extracellular signals enables cells to make decisions in constantly fluctuating environments. It is currently not well understood how mammalian signaling networks store the memories of past stimuli a
Externí odkaz:
https://doaj.org/article/c59fa05d68b94b3da177fd7394b59b45
Publikováno v:
eLife, Vol 8 (2019)
Functional conservation is known to constrain protein evolution. Nevertheless, the long-term divergence patterns of proteins maintaining the same molecular function and the possible limits of this divergence have not been explored in detail. We inves
Externí odkaz:
https://doaj.org/article/f05496596e4847a6ac2c657d10d65cf6
Autor:
Hoda Eydgahi, William W Chen, Jeremy L Muhlich, Dennis Vitkup, John N Tsitsiklis, Peter K Sorger
Publikováno v:
Molecular Systems Biology, Vol 9, Iss 1, Pp 1-17 (2013)
Abstract Using models to simulate and analyze biological networks requires principled approaches to parameter estimation and model discrimination. We use Bayesian and Monte Carlo methods to recover the full probability distributions of free parameter
Externí odkaz:
https://doaj.org/article/b00735b9ca8340b3a718ad88b7740f8a
Publikováno v:
Molecular Systems Biology, Vol 6, Iss 1, Pp 1-15 (2010)
Abstract Genome‐scale metabolic reconstructions can serve as important tools for hypothesis generation and high‐throughput data integration. Here, we present a metabolic network reconstruction and flux‐balance analysis (FBA) of Plasmodium falci
Externí odkaz:
https://doaj.org/article/aa54f29d20cf486f8ff7286518d9e058
Autor:
Brian P Anton, Yi-Chien Chang, Peter Brown, Han-Pil Choi, Lina L Faller, Jyotsna Guleria, Zhenjun Hu, Niels Klitgord, Ami Levy-Moonshine, Almaz Maksad, Varun Mazumdar, Mark McGettrick, Lais Osmani, Revonda Pokrzywa, John Rachlin, Rajeswari Swaminathan, Benjamin Allen, Genevieve Housman, Caitlin Monahan, Krista Rochussen, Kevin Tao, Ashok S Bhagwat, Steven E Brenner, Linda Columbus, Valérie de Crécy-Lagard, Donald Ferguson, Alexey Fomenkov, Giovanni Gadda, Richard D Morgan, Andrei L Osterman, Dmitry A Rodionov, Irina A Rodionova, Kenneth E Rudd, Dieter Söll, James Spain, Shuang-Yong Xu, Alex Bateman, Robert M Blumenthal, J Martin Bollinger, Woo-Suk Chang, Manuel Ferrer, Iddo Friedberg, Michael Y Galperin, Julien Gobeill, Daniel Haft, John Hunt, Peter Karp, William Klimke, Carsten Krebs, Dana Macelis, Ramana Madupu, Maria J Martin, Jeffrey H Miller, Claire O'Donovan, Bernhard Palsson, Patrick Ruch, Aaron Setterdahl, Granger Sutton, John Tate, Alexander Yakunin, Dmitri Tchigvintsev, Germán Plata, Jie Hu, Russell Greiner, David Horn, Kimmen Sjölander, Steven L Salzberg, Dennis Vitkup, Stanley Letovsky, Daniel Segrè, Charles DeLisi, Richard J Roberts, Martin Steffen, Simon Kasif
Publikováno v:
PLoS Biology, Vol 11, Iss 8, p e1001638 (2013)
Externí odkaz:
https://doaj.org/article/08400167d9dc4fa29d1dc69cd0f6756f
Autor:
Tzu-Lin Hsiao, Dennis Vitkup
Publikováno v:
PLoS Genetics, Vol 4, Iss 3, p e1000014 (2008)
It is now widely recognized that robustness is an inherent property of biological systems [1],[2],[3]. The contribution of close sequence homologs to genetic robustness against null mutations has been previously demonstrated in simple organisms [4],[
Externí odkaz:
https://doaj.org/article/4e90ac74f69149eb9a3abc0d2e347ab4
Autor:
Anna Dickson, Tekle Pauzaite, Esther Arnaiz, Brian Ortmann, James West, Norbert Volkmar, Anthony Martinelli, Zhaoqi Li, Niek Wit, Dennis Vitkup, Arthur Kaser, Paul Lehner, James Nathan
Cholesterol biosynthesis is a highly regulated, oxygen-dependent pathway, vital for cell membrane integrity and growth. In fungi, the dependency on oxygen for sterol production has resulted in a shared transcriptional response, resembling prolyl hydr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa9ec80cc62ffca30e87333f4867a204
https://doi.org/10.21203/rs.3.rs-2579549/v1
https://doi.org/10.21203/rs.3.rs-2579549/v1
