Zobrazeno 1 - 10
of 137
pro vyhledávání: '"Dennis Vitkup"'
Autor:
Anna S. Dickson, Tekle Pauzaite, Esther Arnaiz, Brian M. Ortmann, James A. West, Norbert Volkmar, Anthony W. Martinelli, Zhaoqi Li, Niek Wit, Dennis Vitkup, Arthur Kaser, Paul J. Lehner, James A. Nathan
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Cholesterol biosynthesis is a highly regulated, oxygen-dependent pathway, vital for cell membrane integrity and growth. In fungi, the dependency on oxygen for sterol production has resulted in a shared transcriptional response, resembling pr
Externí odkaz:
https://doaj.org/article/c87d491caba847fcaeae18fb670de9f1
Autor:
Anna S. Dickson, Tekle Pauzaite, Esther Arnaiz, Brian M. Ortmann, James A. West, Norbert Volkmar, Anthony W. Martinelli, Zhaoqi Li, Niek Wit, Dennis Vitkup, Arthur Kaser, Paul J. Lehner, James A. Nathan
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/1e8df5e5952f458ba4cea0c1b5668fea
Autor:
Anna S. Dickson, Tekle Pauzaite, Esther Arnaiz, Brian M. Ortmann, James A. West, Norbert Volkmar, Anthony W. Martinelli, Zhaoqi Li, Niek Wit, Dennis Vitkup, Arthur Kaser, Paul J. Lehner, James A. Nathan
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/2599fb5071604775b7eff4fa0c444bd5
Autor:
Eugenia Lyashenko, Mario Niepel, Purushottam D Dixit, Sang Kyun Lim, Peter K Sorger, Dennis Vitkup
Publikováno v:
eLife, Vol 9 (2020)
Detecting relative rather than absolute changes in extracellular signals enables cells to make decisions in constantly fluctuating environments. It is currently not well understood how mammalian signaling networks store the memories of past stimuli a
Externí odkaz:
https://doaj.org/article/c59fa05d68b94b3da177fd7394b59b45
Publikováno v:
eLife, Vol 8 (2019)
Functional conservation is known to constrain protein evolution. Nevertheless, the long-term divergence patterns of proteins maintaining the same molecular function and the possible limits of this divergence have not been explored in detail. We inves
Externí odkaz:
https://doaj.org/article/f05496596e4847a6ac2c657d10d65cf6
Autor:
Anna Dickson, Tekle Pauzaite, Esther Arnaiz, Brian Ortmann, James West, Norbert Volkmar, Anthony Martinelli, Zhaoqi Li, Niek Wit, Dennis Vitkup, Arthur Kaser, Paul Lehner, James Nathan
Cholesterol biosynthesis is a highly regulated, oxygen-dependent pathway, vital for cell membrane integrity and growth. In fungi, the dependency on oxygen for sterol production has resulted in a shared transcriptional response, resembling prolyl hydr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa9ec80cc62ffca30e87333f4867a204
https://doi.org/10.21203/rs.3.rs-2579549/v1
https://doi.org/10.21203/rs.3.rs-2579549/v1
Autor:
Sharanya Sivanand, Yetis Gultekin, Peter S. Winter, Sidney Y. Vermeulen, Konstantine Tchourine, Laura V. Danai, Brian T. Do, Kayla Crowder, Tenzin Kunchok, Allison N. Lau, Alicia M. Darnell, Satoru Morita, Dan G. Duda, Andrew Aguirre, Brian M. Wolpin, Caroline A. Lewis, Dennis Vitkup, Alex K. Shalek, Matthew G. Vander Heiden
Metastases arise from a subset of cancer cells that disseminate from the primary tumor; however, the factors that contribute to proliferation of cancer cells in a secondary site are incompletely understood. The ability of cancer cells to thrive in a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::35609d6038e328628d4549bfd6c98408
https://doi.org/10.1101/2022.08.17.504141
https://doi.org/10.1101/2022.08.17.504141
Autor:
Zhaoqi Li, Brian W. Ji, Purushottam D. Dixit, Konstantine Tchourine, Evan C. Lien, Aaron M. Hosios, Keene L. Abbott, Justine C. Rutter, Anna M. Westermark, Elizabeth F. Gorodetsky, Lucas B. Sullivan, Matthew G. Vander Heiden, Dennis Vitkup
Publikováno v:
Nat Metab
Production of oxidized biomass, which requires regeneration of the cofactor NAD+, can be a proliferation bottleneck that is influenced by environmental conditions. However, a comprehensive quantitative understanding of metabolic processes that may be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::754ddc49204415185a466d4ae8b80af3
https://europepmc.org/articles/PMC10305743/
https://europepmc.org/articles/PMC10305743/
Autor:
Hoda Eydgahi, William W Chen, Jeremy L Muhlich, Dennis Vitkup, John N Tsitsiklis, Peter K Sorger
Publikováno v:
Molecular Systems Biology, Vol 9, Iss 1, Pp 1-17 (2013)
Abstract Using models to simulate and analyze biological networks requires principled approaches to parameter estimation and model discrimination. We use Bayesian and Monte Carlo methods to recover the full probability distributions of free parameter
Externí odkaz:
https://doaj.org/article/b00735b9ca8340b3a718ad88b7740f8a
Publikováno v:
Nature Microbiology. 5:768-775
The gut microbiota is now widely recognized as a dynamic ecosystem that plays an important role in health and disease. Although current sequencing technologies make it possible to explore how relative abundances of host-associated bacteria change ove
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07b619461bd341a290bff377eac1bac0
https://doi.org/10.1038/s41564-020-0685-1
https://doi.org/10.1038/s41564-020-0685-1