Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Dennis Solas"'
Autor:
Maya Michon, Andreas Müller-Schiffmann, Anuradha F. Lingappa, Shao Feng Yu, Li Du, Fred Deiter, Sean Broce, Suguna Mallesh, Jackelyn Crabtree, Usha F. Lingappa, Amanda Macieik, Lisa Müller, Philipp Niklas Ostermann, Marcel Andrée, Ortwin Adams, Heiner Schaal, Robert J. Hogan, Ralph A. Tripp, Umesh Appaiah, Sanjeev K. Anand, Thomas W. Campi, Michael J. Ford, Jonathan C. Reed, Jim Lin, Olayemi Akintunde, Kiel Copeland, Christine Nichols, Emma Petrouski, Ana R. Moreira, I-ting Jiang, Nicholas DeYarman, Ian Brown, Sharon Lau, Ilana Segal, Danielle Goldsmith, Shi Hong, Vinod Asundi, Erica M. Briggs, Ngwe Sin Phyo, Markus Froehlich, Bruce Onisko, Kent Matlack, Debendranath Dey, Jaisri R. Lingappa, Dharma M. Prasad, Anatoliy Kitaygorodskyy, Dennis Solas, Homer Boushey, John Greenland, Satish Pillai, Michael K. Lo, Joel M. Montgomery, Christina F. Spiropoulou, Carsten Korth, Suganya Selvarajah, Kumar Paulvannan, Vishwanath R. Lingappa
Publikováno v:
Open Biology, Vol 14, Iss 6 (2024)
We present a novel small molecule antiviral chemotype that was identified by an unconventional cell-free protein synthesis and assembly-based phenotypic screen for modulation of viral capsid assembly. Activity of PAV-431, a representative compound fr
Externí odkaz:
https://doaj.org/article/ab895c6ab92c405ab16479c74bcf64ea
Autor:
Anuradha F. Lingappa, Olayemi Akintunde, Connie Ewald, Markus Froehlich, Niloufar Ziari, Shao Feng Yu, Maya Michon, Suguna Mallesh, Jim Lin, Anatoliy Kitaygorodskyy, Dennis Solas, Jonathan C. Reed, Jaisri R. Lingappa, Andreas Mueller-Schiffmann, Carsten Korth, Dharma Prasad, Aysegul Nalca, Emily Ashton, Brad Fabbri, Emma Petrouski, Debendranath Dey, David Andrews, Vishwanath R. Lingappa
Two structurally-unrelated small molecule chemotypes, represented by compounds PAV-617 and PAV-951, with antiviral activity in cell culture against monkeypox virus (MPXV) and human immunodeficiency virus (HIV) respectively, were studied for anti-canc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d1b819f47aacf2e88dedce28b0b3a974
https://doi.org/10.1101/2022.09.28.509937
https://doi.org/10.1101/2022.09.28.509937
Autor:
Andreas Müller-Schiffmann, Felix Torres, Anatolly Kitaygorodskyy, Anand Ramani, Argyro Alatza, Sarah K. Tschirner, Ingrid Prikulis, Shaofeng Yu, Debendranath Dey, Suguna Mallesh, Dharma Prasad, Dennis Solas, Verian Bader, Annemieke Rozemuller, Selina Wray, Jay Gopalakrishnan, Roland Riek, Vishwanath R. Lingappa, Carsten Korth
Herpes virus infections are endemic and ubiquitous. While only rarely leading to overt encephalitis, subchronic or latent infections have been associated to a variety of conditions, including Alzheimers disease (AD). The cellular consequences of herp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68a74e74e31947d49a74e2310209962a
https://doi.org/10.1101/2021.09.11.459903
https://doi.org/10.1101/2021.09.11.459903
Autor:
Andreas Müller-Schiffmann, Maya Michon, Anuradha F. Lingappa, Shao Feng Yu, Li Du, Fred Deiter, Sean Broce, Suguna Mallesh, Jackelyn Crabtree, Usha F. Lingappa, Amanda Macieik, Lisa Müller, Philipp Niklas Ostermann, Marcel Andrée, Ortwin Adams, Heiner Schaal, Robert J. Hogan, Ralph A. Tripp, Umesh Appaiah, Sanjeev K. Anand, Thomas W. Campi, Michael J. Ford, Jonathan C. Reed, Jim Lin, Olayemi Akintunde, Kiel Copeland, Christine Nichols, Emma Petrouski, A. Raquel Moreira, I-ting Jiang, Nicholas DeYarman, Ian Brown, Sharon Lau, Ilana Segal, Danielle Goldsmith, Shi Hong, Vinod Asundi, Erica M. Briggs, Ngwe Sin Phyo, Markus Froehlich, Bruce Onisko, Kent Matlack, Debendranath Dey, Jaisri R. Lingappa, M. Dharma Prasad, Anatoliy Kitaygorodskyy, Dennis Solas, Homer Boushey, John Greenland, Satish Pillai, Michael K. Lo, Joel M. Montgomery, Christina F. Spiropoulou, Carsten Korth, Suganya Selvarajah, Kumar Paulvannan, Vishwanath R. Lingappa
Publikováno v:
bioRxiv
Antiviral compounds displaying several remarkable features have been identified by a uniquely enabling drug screen and advanced through validation in two animal models, and in human primary bronchial epithelial cells grown to an air-liquid interface
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07e3f5d517503bbb152583a4089fda76
https://doi.org/10.1101/2021.01.17.426875
https://doi.org/10.1101/2021.01.17.426875
Autor:
Jonathan C. Reed, Kent Matlack, Daryl J. Phuong, J. Victor Swain, Clarence R. Hurt, Beverly Freeman, Jaisri R. Lingappa, Dennis Solas, Dylan T. B. Ressler, Anatoliy Kitaygorodskyy, Vishwanath R. Lingappa
Publikováno v:
Journal of Virology
The success of antiretroviral treatment for HIV-1 is at risk of being undermined by the growing problem of drug resistance. Thus, there is a need to identify antiretrovirals that act on viral life cycle stages not targeted by drugs in use, such as th
Autor:
Joseph M. Muchowski, Dean R. Artis, Thomas T. Tidwell, Dennis Solas, Peter H. Mathies, Reto Naef, Brian L. Bray
Publikováno v:
ChemInform. 22
A most useful strategy has been devised for the synthesis of 3-substituted pyrroles on the basis of the kinetic electrophilic substitution of 1-(triisopropylsilyl) pyrrole (1) at the β position and subsequent fluoride ion induced desilylation. This
Autor:
Brian L. Bray, Thomas T. Tidwell, Joseph M. Muchowski, Reto Naef, Dean R. Artis, Dennis Solas, Peter H. Mathies
Publikováno v:
The Journal of Organic Chemistry. 55:6317-6328
A most useful strategy has been devised for the synthesis of 3-substituted pyrroles on the basis of the kinetic electrophilic substitution of 1-(triisopropylsilyl) pyrrole (1) at the β position and subsequent fluoride ion induced desilylation. This
Publikováno v:
The Journal of Organic Chemistry. 61:1537-1539
Publikováno v:
Pharmaceutical Research; Feb2007, Vol. 24 Issue 2, p336-342, 7p
Autor:
Dennis Solas, Joseph Wolinsky
Publikováno v:
The Journal of Organic Chemistry. 48:670-673