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Autor:
Mark Bradshaw, Dennis Sharkey, Dolphus R. Dawson, Clay Walker, Randal W. Rowland, M. John Novak, John G. Thomas, William V. Giannobile, Alan M. Polson, Philip M. Preshaw, Ingvar Magnusson, James T. Mellonig
Publikováno v:
Journal of Periodontology. 79:440-452
Previous studies showed that adjunctive subantimicrobial dose doxycycline (SDD; 20 mg, twice daily) provides significant clinical benefits to scaling and root planing (SRP). A modified-release SDD formulation containing 40 mg doxycycline (SDD-40) to