Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Dennis Segebarth"'
Autor:
Matthias Griebel, Dennis Segebarth, Nikolai Stein, Nina Schukraft, Philip Tovote, Robert Blum, Christoph M. Flath
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
The signal-to-noise ratio in bioimages is often low, which is problematic for segmentation. Here the authors report a deep learning method, deepflash2, to facilitate the segmentation of ambiguous bioimages through multi-expert annotations and integra
Externí odkaz:
https://doaj.org/article/7de380a95c5a4512844457ad18074389
Autor:
Radostina Lyutova, Mareike Selcho, Maximilian Pfeuffer, Dennis Segebarth, Jens Habenstein, Astrid Rohwedder, Felix Frantzmann, Christian Wegener, Andreas S. Thum, Dennis Pauls
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Olfactory information from Kenyon cells in the mushroom body and reward information from pPAM dopaminergic neurons is required for appetitive olfactory learning and memory. Here, the authors report evidence for a feedback circuit mechanism between Ke
Externí odkaz:
https://doaj.org/article/9ce7f6d4b9a646d398b185181427e064
Autor:
Dennis Segebarth, Matthias Griebel, Nikolai Stein, Cora R von Collenberg, Corinna Martin, Dominik Fiedler, Lucas B Comeras, Anupam Sah, Victoria Schoeffler, Teresa Lüffe, Alexander Dürr, Rohini Gupta, Manju Sasi, Christina Lillesaar, Maren D Lange, Ramon O Tasan, Nicolas Singewald, Hans-Christian Pape, Christoph M Flath, Robert Blum
Publikováno v:
eLife, Vol 9 (2020)
Bioimage analysis of fluorescent labels is widely used in the life sciences. Recent advances in deep learning (DL) allow automating time-consuming manual image analysis processes based on annotated training data. However, manual annotation of fluores
Externí odkaz:
https://doaj.org/article/ac0ffdcd78dc4ad080ed0dc01533019f
Autor:
Julia Doll, Michaela A. H. Hofrichter, Paulina Bahena, Alfred Heihoff, Dennis Segebarth, Tobias Müller, Marcus Dittrich, Thomas Haaf, Barbara Vona
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 8, Iss 8, Pp n/a-n/a (2020)
Abstract Background MYO3A, encoding the myosin IIIA protein, is associated with autosomal recessive and autosomal dominant nonsyndromic hearing loss. To date, only two missense variants located in the motor‐head domain of MYO3A have been described
Externí odkaz:
https://doaj.org/article/e3a28149327449109b326fcf9b72c593
Autor:
Jérémy Signoret-Genest, Nina Schukraft, Sara L. Reis, Dennis Segebarth, Karl Deisseroth, Philip Tovote
Publikováno v:
Nature Neuroscience. 26:447-457
Fear and anxiety are brain states that evolved to mediate defensive responses to threats. The defense reaction includes multiple interacting behavioral, autonomic and endocrine adjustments, but their integrative nature is poorly understood. In partic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8192f02f343ff264c248c0f83365de81
https://doi.org/10.1038/s41593-022-01252-w
https://doi.org/10.1038/s41593-022-01252-w
Fear and anxiety are brain states that evolved to mediate defensive responses to threat. While it is clear that the defense reaction includes multiple interacting behavioural, autonomic and endocrine adjustments, their integrative nature is poorly un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::14345e43c60f9d0f05ba651c9ff711ef
https://doi.org/10.1101/2022.09.22.509009
https://doi.org/10.1101/2022.09.22.509009
Autor:
Annemarie Schulte, Hannah Lohner, Johannes Degenbeck, Dennis Segebarth, Heike L. Rittner, Robert Blum, Annemarie Aue
Publikováno v:
Pain.
Pain syndromes are often accompanied by complex molecular and cellular changes in dorsal root ganglia (DRG). However, the evaluation of cellular plasticity in the DRG is often performed by heuristic manual analysis of a small number of representative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d7e319d13cdd7d99596e08566de7da1
https://pubmed.ncbi.nlm.nih.gov/35969236
https://pubmed.ncbi.nlm.nih.gov/35969236
Autor:
Anupam Sah, Dennis Segebarth, Nikolai Stein, Christoph M. Flath, Robert Blum, Hans-Christian Pape, Christina Lillesaar, Maren D. Lange, Dominik Fiedler, Ramon O. Tasan, Matthias Griebel, Teresa M. Lüffe, Corinna Martin, Nicolas Singewald, Rohini Gupta, Lucas B. Comeras, Manju Sasi, Cora R. von Collenberg, Alexander Dürr, Victoria Schoeffler
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d2b5b1eb1d68795e3e41dae52a2399c
https://doi.org/10.7554/elife.59780.sa2
https://doi.org/10.7554/elife.59780.sa2
Autor:
Britta Wachter, Patrick Lüningschrör, Camelia M. Monoranu, Jochen Kuper, Elena Bady, Dennis Segebarth, Gisela Wohlleben, Bülent Polat, Rohini Gupta, Robert Blum, Melanie Bauer, Vanessa Luzak, Carmen Villmann, Steven Havlicek, Vanessa Wegat, Georg Langlhofer
Trk receptors and gene fusions of NTRK are targets in precision oncology. Classical Trk signalling concepts fail to explain ligand-independent signalling of intracellular TrkB or NTRK fusion proteins. Here, we show that abundance of the intracellular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::409f5e480533197bebb221e91ef20742
https://doi.org/10.1101/2020.09.11.292565
https://doi.org/10.1101/2020.09.11.292565
Autor:
Barbara Vona, Alfred Heihoff, Thomas Haaf, Michaela A.H. Hofrichter, Marcus Dittrich, Tobias Müller, Paulina Bahena, Dennis Segebarth, Julia Doll
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 8, Iss 8, Pp n/a-n/a (2020)
Molecular Genetics & Genomic Medicine
Molecular Genetics & Genomic Medicine
Background MYO3A, encoding the myosin IIIA protein, is associated with autosomal recessive and autosomal dominant nonsyndromic hearing loss. To date, only two missense variants located in the motor‐head domain of MYO3A have been described in autoso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89c2aeeca3c490155301ddede1b4dfb5
https://doaj.org/article/e3a28149327449109b326fcf9b72c593
https://doaj.org/article/e3a28149327449109b326fcf9b72c593