Zobrazeno 1 - 10
of 152
pro vyhledávání: '"Dennis R. Petersen"'
Autor:
Colin T. Shearn, Kristofer S. Fritz, Alisabeth H. Shearn, Laura M. Saba, Kelly E. Mercer, Bridgette Engi, James J. Galligan, Piotr Zimniak, David J. Orlicky, Martin J. Ronis, Dennis R. Petersen
Publikováno v:
Redox Biology, Vol 7, Iss C, Pp 68-77 (2016)
Chronic alcohol consumption induces hepatic oxidative stress resulting in production of highly reactive electrophilic α/β-unsaturated aldehydes that have the potential to modify proteins. A primary mechanism of reactive aldehyde detoxification by h
Externí odkaz:
https://doaj.org/article/a0c8a20508814e5c97a8857b03dd80be
Autor:
Rebecca L. Smathers, James J. Galligan, Colin T. Shearn, Kristofer S. Fritz, Kelly Mercer, Martin Ronis, David J. Orlicky, Nicholas O. Davidson, Dennis R. Petersen
Publikováno v:
Journal of Lipid Research, Vol 54, Iss 5, Pp 1335-1345 (2013)
Chronic ethanol consumption is a prominent cause of liver disease worldwide. Dysregulation of an important lipid uptake and trafficking gene, liver-fatty acid binding protein (L-FABP), may contribute to alterations in lipid homeostasis during early-s
Externí odkaz:
https://doaj.org/article/b603cc7b2f05490b972ebda2bad506c4
Autor:
Kusum K. Kharbanda, Martin J. J. Ronis, Colin T. Shearn, Dennis R. Petersen, Samir Zakhari, Dennis R. Warner, Ariel E. Feldstein, Craig J. McClain, Irina A. Kirpich
Publikováno v:
Biomolecules, Vol 8, Iss 2, p 16 (2018)
The symposium, “Role of Nutrition in Alcoholic Liver Disease”, was held at the European Society for Biomedical Research on Alcoholism Congress on 9 October 2017 in Crete, Greece. The goal of the symposium was to highlight recent advances and deve
Externí odkaz:
https://doaj.org/article/178f7ffe49004c18b943379b96dcb7ba
Autor:
James J. Galligan, Rebecca L. Smathers, Colin T. Shearn, Kristofer S. Fritz, Donald S. Backos, Hua Jiang, Christopher C. Franklin, David J. Orlicky, Kenneth N. MacLean, Dennis R. Petersen
Publikováno v:
Journal of Toxicology, Vol 2012 (2012)
Alcoholic liver disease (ALD) is a primary cause of morbidity and mortality in the United States and constitutes a significant socioeconomic burden. Previous work has implicated oxidative stress and endoplasmic reticulum (ER) stress in the etiology o
Externí odkaz:
https://doaj.org/article/bc997f31c12d464188ce5ec19231de24
Autor:
Colin T. Shearn, Aimee L. Anderson, Michael W. Devereux, David J. Orlicky, Cole Michel, Dennis R. Petersen, Colin G. Miller, Sanjiv Harpavat, Edward E. Schmidt, Ronald J. Sokol
Publikováno v:
PloS one. 17(11)
Inflammatory cholestatic liver diseases, including Primary Sclerosing Cholangitis (PSC), are characterized by periportal inflammation with progression to cirrhosis. The objective of this study was to examine interactions between oxidative stress and
Autor:
David J. Orlicky, Kyle Meredith, Dennis R. Petersen, Kelly E. Mercer, Casey F. Pulliam, Martin J. J. Ronis, Colin T. Shearn, Laura Saba, Kim Brint Pedersen
Publikováno v:
Alcoholism: Clinical and Experimental Research. 42:1192-1205
BACKGROUND: Glutathione-S-transferase A4-4 (GSTA4) is a key enzyme for removal of toxic lipid peroxidation products such as 4-hydroxynonenal (4-HNE). In the current study, we examined the potential role of GSTA4 on protein carbonylation and progressi
Autor:
Colin T. Shearn, Laura Saba, David J. Orlicky, James R. Roede, Alisabeth H. Shearn, Dennis R. Petersen
Publikováno v:
Free Radical Biology and Medicine. 113:280-290
In the liver, a contributing factor in the pathogenesis of non-alcoholic fatty liver disease is oxidative stress leading to the accumulation of highly reactive electrophilic α/β unsaturated aldehydes. The objective of this study was to determine if
Autor:
David J. Orlicky, Natarajan Balasubramaniyan, Colin T. Shearn, Ronald J. Sokol, Dennis R. Petersen, Aimee L. Anderson, Michael W. Devereaux, Frederick J. Suchy
Publikováno v:
Gastroenterology. 160:S-768
Autor:
Alisabeth H. Shearn, David J. Orlicky, Bridgette Engi, Kelly E. Mercer, Dennis R. Petersen, Piotr Zimniak, Colin T. Shearn, James J. Galligan, Martin J. J. Ronis, Laura Saba, Kristofer S. Fritz
Publikováno v:
Redox Biology, Vol 7, Iss C, Pp 68-77 (2016)
Redox Biology
Redox Biology
Chronic alcohol consumption induces hepatic oxidative stress resulting in production of highly reactive electrophilic α/β-unsaturated aldehydes that have the potential to modify proteins. A primary mechanism of reactive aldehyde detoxification by h
Autor:
Samir Zakhari, Dennis R. Petersen, Dennis R. Warner, Martin J. J. Ronis, Kusum K. Kharbanda, Craig J. McClain, Colin T. Shearn, Ariel E. Feldstein, Irina A. Kirpich
Publikováno v:
Biomolecules
Biomolecules, vol 8, iss 2
Biomolecules, Vol 8, Iss 2, p 16 (2018)
Biomolecules, vol 8, iss 2
Biomolecules, Vol 8, Iss 2, p 16 (2018)
The symposium, "Role of Nutrition in Alcoholic Liver Disease", was held at the European Society for Biomedical Research on Alcoholism Congress on 9 October 2017 in Crete, Greece. The goal of the symposium was to highlight recent advances and developm