Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Dennis R. Carty"'
Autor:
Dennis R. Carty, Cammi Thornton, Marisa L. Kutchma, Zacharias Pandelides, Kristine L. Willett, Zachary S. Miller
Publikováno v:
Toxicology and Applied Pharmacology. 364:133-143
While Δ9-tetrahydrocannabinol (THC) has been widely studied in the realm of developmental and reproductive toxicology, few studies have investigated potential toxicities from a second widely used cannabis constituent, cannabidiol (CBD). CBD is popul
Autor:
Paige C, Mundy, Brandon, Pressly, Dennis R, Carty, Bianca, Yaghoobi, Heike, Wulff, Pamela J, Lein
Publikováno v:
Toxicology and applied pharmacology
The chemical threat agent tetramethylenedisulfotetramine (TETS) is a γ-aminobutyric acid type A receptor (GABA AR) antagonist that causes life threatening seizures. Currently, there is no specific antidote for TETS intoxication. TETS-induced seizure
Publikováno v:
Environmental Toxicology and Chemistry. 37:3018-3024
Silver nanoparticles (Ag-NPs) are ubiquitous in household and medical products because of their antimicrobial activity. A consequence of the high volume of Ag-NP production and usage is increased amounts of Ag-NPs released into the environment. Their
Autor:
Kelly M Morales, Dennis R. Carty, Katharina Dach, Bianca Yaghoobi, Pamela J. Lein, Martin Schmuck
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology, vol 167, iss 1
To screen the tens of thousands of chemicals for which no toxicity data currently exists, it is necessary to move from in vivo rodent models to alternative models, such as zebrafish. Here, we used dechorionated Tropical 5D wild-type zebrafish embryos
Publikováno v:
Chemosphere. 186:901-910
Evidence indicated ethanol exposure during development disrupts brain functions that induces fetal alcohol spectrum disorder (FASD) phenotypes with behavioral abnormalities. We aimed to investigate whether prenatal ethanol exposure has any potential
Publikováno v:
Bulletin of Environmental Contamination and Toxicology. 98:753-757
The purpose of this study was to evaluate the steroidogenic effects of sertraline, a popular selective serotonin reuptake inhibitor, on larval fathead minnow (FHM; Pimephales promelas) and adult FHM. Larvae were exposed to 0.1, 1, and 10 µg/L sertra
Autor:
Brandon Pressly, Suren B. Bandara, Vikrant Singh, Danielle J Harvey, Pamela J. Lein, Heike Wulff, Natalia Vasylieva, Dennis R. Carty
Publikováno v:
Neurotoxicology
Previous studies demonstrated that pentylenetetrazole (PTZ), a GABA type A receptor (GABA(A)R) antagonist, elicits seizure-like phenotypes in larval zebrafish (Danio rerio). Here, we determined whether the GABA(A)R antagonists, tetramethylenedisulfot
Publikováno v:
Epilepsy Behav
Current antiepileptic drugs (AEDs) are undesirable for many reasons including the inability to reduce seizures in certain types of epilepsy, such as Dravet syndrome (DS) where in one-third of patients does not respond to current AEDs, and severe adve
Publikováno v:
Environmental toxicology and chemistry. 37(12)
Silver nanoparticles (Ag-NPs) are ubiquitous in household and medical products because of their antimicrobial activity. A consequence of the high volume of Ag-NP production and usage is increased amounts of Ag-NPs released into the environment. Their
Autor:
Dennis R. Carty, Lene H. Petersen, Dalma Martinović, Mark Cantu, David Hala, Duane B. Huggett
Publikováno v:
Environmental Toxicology and Chemistry. 34:379-390
As knowledge of contaminants capable of adversely modulating endocrine functions increases, attention is focused on the effects of synthetic progestins as environmental endocrine disrupters. In the present study, effects of exposure to a synthetic pr