Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Dennis P. Stegmann"'
Autor:
Guillaume Gotthard, Andrea Flores-Ibarra, Melissa Carrillo, Michal W. Kepa, Thomas J. Mason, Dennis P. Stegmann, Bence Olasz, Magdalena Pachota, Florian Dworkowski, Dmitry Ozerov, Bill F. Pedrini, Celestino Padeste, John H. Beale, Przemyslaw Nogly
Publikováno v:
IUCrJ, Vol 11, Iss 5, Pp 749-761 (2024)
X-ray free-electron laser (XFEL) light sources have enabled the rapid growth of time-resolved structural experiments, which provide crucial information on the function of macromolecules and their mechanisms. Here, the aim was to commission the SwissM
Externí odkaz:
https://doaj.org/article/28a1c630a73b4cb6a426ea3c75b3232b
Autor:
Franziska Leipoldt, Javier Santos-Aberturas, Dennis P. Stegmann, Felix Wolf, Andreas Kulik, Rodney Lacret, Désirée Popadić, Daniela Keinhörster, Norbert Kirchner, Paulina Bekiesch, Harald Gross, Andrew W. Truman, Leonard Kaysser
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Metalloproteinase inhibitors are leads for drug development, but their biosynthetic pathways are often unknown. Here the authors show that the acyl branched warhead of actinonin and matlystatins derives from an ethylmalonyl-CoA-like pathway and the s
Externí odkaz:
https://doaj.org/article/33d55bdb2e15447e910a355a7a9c3566
Autor:
Michael Bott, Jochem Gätgens, Jörg Simon, Sascha Hein, Andrej Trautmann, Dennis P. Stegmann, Julia Steuber, Lena Schleicher, Jana Seifert, Günter Fritz
Publikováno v:
Applied and environmental microbiology 87(21), e01211-21 (2021). doi:10.1128/AEM.01211-21
Applied and Environmental Microbiology
Applied and Environmental Microbiology
Ruminants such as cattle and sheep depend on the breakdown of carbohydrates from plant-based feedstuff, which is accomplished by the microbial community in the rumen. Roughly 40% of the members of the rumen microbiota belong to the family Prevotellac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::906573299bbd6a308ef76490e06b9869
https://juser.fz-juelich.de/record/904487
https://juser.fz-juelich.de/record/904487
Autor:
Hamid R. Nasiri, Karina Tuz, Iris Bischoff, Robert Fürst, Zhenyu Han, Oscar Juárez, Yihan Qin, Günter Fritz, Heike Angerer, Dana Lashley, Dennis P. Stegmann
Publikováno v:
ChemMedChem. 15(24)
A short, efficient one-step synthesis of 2-methyl-5-(3-methyl-2-butenyl)-1,4-benzoquinone, a natural product from Pyrola media is described. The synthesis is based on a direct late C-H functionalization of the quinone scaffold. The formation of the n
Autor:
Andrew W. Truman, Paulina Bekiesch, Leonard Kaysser, Rodney Lacret, Daniela Keinhörster, Franziska Leipoldt, Désirée Popadić, Andreas Kulik, Harald Gross, Felix Wolf, Javier Santos-Aberturas, Dennis P. Stegmann, Norbert Kirchner
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Nature Communications
Nature Communications
Metalloproteinase inhibitors often feature hydroxamate moieties to facilitate the chelation of metal ions in the catalytic center of target enzymes. Actinonin and matlystatins are potent metalloproteinase inhibitors that comprise rare N-hydroxy-2-pen