Zobrazeno 1 - 10
of 741
pro vyhledávání: '"Dennis P. Curran"'
Autor:
Andreas Vogt, Billy W. Day, Dennis P. Curran, Neil A. Hukriede, John S. Lazo, Celeste E. Reese, Raghavan Balachandran, Hikmat N. Daghestani, Wei Zhu, Daniel P. Camarco, Maria Jiménez, Laura L. Vollmer
Supplementary Tables 1-2,Characterization Data & References from A Simplified Synthesis of Novel Dictyostatin Analogues with In Vitro Activity against Epothilone B–Resistant Cells and Antiangiogenic Activity in Zebrafish Embryos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32fec54cded103cf86b1a690df8d0627
https://doi.org/10.1158/1535-7163.22497030.v1
https://doi.org/10.1158/1535-7163.22497030.v1
Autor:
Andreas Vogt, Billy W. Day, Dennis P. Curran, Neil A. Hukriede, John S. Lazo, Celeste E. Reese, Raghavan Balachandran, Hikmat N. Daghestani, Wei Zhu, Daniel P. Camarco, Maria Jiménez, Laura L. Vollmer
The natural product (−)-dictyostatin is a microtubule-stabilizing agent that potently inhibits the growth of human cancer cells, including paclitaxel-resistant clones. Extensive structure–activity relationship studies have revealed several region
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ecdf80d5efb235382c6a7baaca49a0a2
https://doi.org/10.1158/1535-7163.c.6535479
https://doi.org/10.1158/1535-7163.c.6535479
Autor:
Andreas Vogt, Billy W. Day, Dennis P. Curran, Neil A. Hukriede, John S. Lazo, Celeste E. Reese, Raghavan Balachandran, Hikmat N. Daghestani, Wei Zhu, Daniel P. Camarco, Maria Jiménez, Laura L. Vollmer
NMR Spectra from A Simplified Synthesis of Novel Dictyostatin Analogues with In Vitro Activity against Epothilone B–Resistant Cells and Antiangiogenic Activity in Zebrafish Embryos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45de1697f469204b948471244ec8f90e
https://doi.org/10.1158/1535-7163.22497033
https://doi.org/10.1158/1535-7163.22497033
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 11, Iss 1, Pp 1649-1655 (2015)
Two new fates of imine intermediates formed on radical cyclizations of ene-sulfonamides have been identified, reduction and hydration/fragmentation. Tin hydride-mediated cyclizations of 2-halo-N-(3-methyl-N-sulfonylindole)anilines provide spiro[indol
Externí odkaz:
https://doaj.org/article/b3a77c3298854450a424d6dfd439496b
Inverse Hydroboration of Imines with NHC-Boranes Is Promoted by Diphenyl Disulfide and Visible Light
Publikováno v:
Organic Letters. 23:1825-1828
We describe a simple and efficient procedure for nucleophilic borylation of imines in the absence of a photoredox catalyst. Visible light irradiation of an acetonitrile solution of an imine, an NHC-borane, and diphenyl disulfide (10 mol %) provides v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff918c3739f93397a6a2edbbcbca121f
https://doi.org/10.1021/acs.orglett.1c00230
https://doi.org/10.1021/acs.orglett.1c00230
Publikováno v:
Organic Letters. 23:1071-1075
Monohydroboration of substituted 1,3-diynes with an N-heterocyclic carbene borane (NHC-borane) occurs under radical conditions using an azo initiator, such as ACCN and AIBN, and a thiol as a polarity-reversal catalyst. The reaction is highly regio- a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ba70f2b147d403a921f9019cbe38f20
https://doi.org/10.1021/acs.orglett.0c04284
https://doi.org/10.1021/acs.orglett.0c04284
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 9, Iss 1, Pp 675-680 (2013)
Acetic acid promotes the reduction of aldehydes and ketones by the readily available N-heterocyclic carbene borane, 1,3-dimethylimidazol-2-ylidene borane. Aldehydes are reduced over 1–24 h at room temperature with 1 equiv of acetic acid and 0.5 equ
Externí odkaz:
https://doaj.org/article/c6edc6b0e2094556be01d3fb6ccba5c8
Autor:
Dennis P. Curran, Steven J. Geib, Masaki Shimoi, Katsuhiro Maeda, Takashi Watanabe, Tsuyoshi Taniguchi, Kosuke Takahashi
Publikováno v:
Organic Letters. 22:2054-2059
Polyfluoroarenes work as good radical acceptors in the thermal radical reaction with N-heterocyclic carbene boranes (NHC-boranes) in the presence of di-tert-butyl peroxide. In this reaction, a C–F ...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8e64a2bc471e19160f5a8a85dc5488f
https://doi.org/10.1021/acs.orglett.0c00481
https://doi.org/10.1021/acs.orglett.0c00481
Publikováno v:
The Journal of Organic Chemistry. 85:4248-4255
J.C.W. thanks EaStCHEM for financial support and D.P.C. thanks the US National Science Foundation. Computational support was provided through the EaStCHEM Research Computing Facility. The boron-centered radicals derived from alkenyl N-heterocyclic ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38b4f9b844ea1a16ef520ee7b88b482d
https://doi.org/10.1021/acs.joc.9b03420
https://doi.org/10.1021/acs.joc.9b03420
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 7, Iss 1, Pp 1372-1378 (2011)
The dictyostatins are powerful microtubule-stabilizing agents that have shown antiproliferative activity against a variety of human cancer cell lines. Two highly active analogs of dictyostatin, 25,26-dihydrodictyostatin and 25,26-dihydro-6-epi-dictyo
Externí odkaz:
https://doaj.org/article/6469f05afa5a45f487e9fdcdd6271564