Zobrazeno 1 - 10 of 14 pro vyhledávání: '"Dennis O. Johnsen"'
1
History of the Use of Nonhuman Primates in Biomedical Research
Autor: Dennis O. Johnsen, David K. Johnson, Robert A. Whitney
The use of nonhuman primates in biomedical research is documented by history's earliest scientists who undoubtedly saw in monkeys and apes the most obvious research surrogates for humans. However, it was not until the 20th century that such use moved
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::22d02c3b02a1fc6868733aca3491e7f1
https://doi.org/10.1016/b978-0-12-381365-7.00001-7
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3
History
Autor: Dennis O. Johnsen
Publisher Summary This chapter outlines the history of primatological knowledge that is generated largely from behavioral and biomedical investigators working independently. The modern use of nonhuman primates in biomedical research has its origin in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6520cc63df87e568e62ff504450eacd0
https://doi.org/10.1016/b978-012088661-6/50003-x
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4
Evaluating New Antimalarial Drugs against Trophozoite Induced Plasmodium Cynomolgi Malaria in Rhesus Monkeys *
Autor: Robert L. Hickman, Kenneth E. Kinnamon, Dennis O. Johnsen, David E. Davidson, Prayot Tanticharoenyos
Publikováno v: The American Journal of Tropical Medicine and Hygiene. 25:26-33
An antimalarial drug testing system is described which utilizes trophozoite induced Plasmodium cynomolgi malaria in rhesus monkeys. The schizonticidal activity of standard antimalarial drugs in this system is reported. The system accurately predicted
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3546b428d30b7aacc7d2b385f5fb9c82
https://doi.org/10.4269/ajtmh.1976.25.26
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7
Acute toxicity of aflatoxin B1 in the macaque monkey*1
Autor: Curtis H. Bourgeois, William L. Wooding, Prayot Tanticharoenyos, Dennis O. Johnsen, Ronald C. Shank
Publikováno v: Toxicology and Applied Pharmacology. 20:227-231
Twenty-four young female macaque monkeys were given 0, 0.5, 1.5, 4.5, 13.5, or 40.5 mg of crystalline aflatoxin B 1 per kg body wt by oral administration. The LD50 for aflatoxin B 1 was 7.8 mg/kg for a test period of 148 hr. Aflatoxin B 1 could be de
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::af33fdbccb32b0134bd2ff7294e920c4
https://doi.org/10.1016/0041-008x(71)90048-2
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9
C-6 oxidation of ascorbic acid: a major metabolic process in animals
Autor: Ronald J. Harkrader, Dennis O. Johnsen, Brendan A. Joyce, Bert M. Tolbert
Publikováno v: Biochemical and biophysical research communications. 71(4)
Metabolic activity of the C-6 carbon of ascorbic acid has been examined using two experimental methods. 43% of the label from ascorbic-6-3H acid is converted to water in the monkey after i.v. injection. The rate of formation of 3H2O corresponds to th
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::284eb04a8d5d52b6e7eea5b1442550a3
https://pubmed.ncbi.nlm.nih.gov/823939
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10
Research Facility Breeding
Autor: Dennis O. Johnsen, Leo A. Whitehair
Publikováno v: Primates ISBN: 9781461293606
More than 30 distinct species of nonhuman primates are currently being bred in U.S. facilities to support biomedical and health research and testing programs conducted or sponsored in more than 45 governmental, academic, commercial, and nonprofit org
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0586fda9c295427ea4512234159e26fd
https://doi.org/10.1007/978-1-4612-4918-4_40
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