Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Dennis Mulac"'
Autor:
Christina Barth, Hendrik Spreen, Dennis Mulac, Lucas Keuter, Matthias Behrens, Hans-Ulrich Humpf, Klaus Langer
Publikováno v:
Biomaterials and Biosystems, Vol 7, Iss , Pp 100057- (2022)
Externí odkaz:
https://doaj.org/article/3a693ab179d54976bca5d599dc51f81e
Autor:
Christina Barth, Hendrik Spreen, Dennis Mulac, Lucas Keuter, Matthias Behrens, Hans-Ulrich Humpf, Klaus Langer
Publikováno v:
Biomaterials and Biosystems, Vol 5, Iss , Pp 100032- (2022)
Receptor-mediated active targeting of nanocarriers is a widely investigated approach to specifically address cancerous cells and tissues in the human body. The idea is to use these formulations as drug carriers with enhanced specificity and therefore
Externí odkaz:
https://doaj.org/article/e4da2ab5791f4bbbbae81e4e2f932853
Autor:
Maria Hahn, Viktoria Lindemann, Matthias Behrens, Dennis Mulac, Klaus Langer, Melanie Esselen, Hans-Ulrich Humpf
Publikováno v:
PLoS ONE, Vol 17, Iss 6 (2022)
Hordenine, a bioactive food compound, has several pharmacological properties and has recently been identified as a dopamine D2 receptor (D2R) agonist. Since the pharmacokinetic profile of hordenine has been described to a limited extent, the present
Externí odkaz:
https://doaj.org/article/d2b45f7325db475cb944ffb067645fd8
Autor:
Sebastian Pieper, Hannah Onafuye, Dennis Mulac, Jindrich Cinatl Jr., Mark N. Wass, Martin Michaelis, Klaus Langer
Publikováno v:
Beilstein Journal of Nanotechnology, Vol 10, Iss 1, Pp 2062-2072 (2019)
Background: Nanoparticles are under investigation as carrier systems for anticancer drugs. The expression of efflux transporters such as the ATP-binding cassette (ABC) transporter ABCB1 is an important resistance mechanism in therapy-refractory cance
Externí odkaz:
https://doaj.org/article/8d1f5de7bcb549f99a9d63b4faf90618
Autor:
Hannah Onafuye, Sebastian Pieper, Dennis Mulac, Jindrich Cinatl Jr., Mark N. Wass, Klaus Langer, Martin Michaelis
Publikováno v:
Beilstein Journal of Nanotechnology, Vol 10, Iss 1, Pp 1707-1715 (2019)
Resistance to systemic drug therapy is a major reason for the failure of anticancer therapies. Here, we tested doxorubicin-loaded human serum albumin (HSA) nanoparticles in the neuroblastoma cell line UKF-NB-3 and its ABCB1-expressing sublines adapte
Externí odkaz:
https://doaj.org/article/5689f5d2bf47444c8e464bfaf5e9ac5a
Publikováno v:
Beilstein Journal of Nanotechnology, Vol 10, Iss 1, Pp 1002-1015 (2019)
Background: When nanoparticles (NPs) are applied into a biological fluid, such as blood, proteins bind rapidly to their surface forming a so-called “protein corona”. These proteins are strongly attached to the NP surface and confers them a new bi
Externí odkaz:
https://doaj.org/article/6d8902745d9249a999eca8b981ad4477
Autor:
Jonas Franz, Jonas Grünebaum, Marcus Schäfer, Dennis Mulac, Florian Rehfeldt, Klaus Langer, Armin Kramer, Christoph Riethmüller
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0189970 (2018)
Symmetry is rarely found on cellular surfaces. An exception is the brush border of microvilli, which are essential for the proper function of transport epithelia. In a healthy intestine, they appear densely packed as a 2D-hexagonal lattice. For in vi
Externí odkaz:
https://doaj.org/article/912d696eb497428eb4d71b954314d046
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0127532 (2015)
Over the last few decades the establishment of nanoparticles as suitable drug carriers with the transport of drugs across biological barriers such as the gastrointestinal barrier moved into the focus of many research groups. Besides drug transport su
Externí odkaz:
https://doaj.org/article/089fef5ca176411c8d54f7d5b68baa73
Autor:
Angelina, Subeska, Jan, Althaus, Theresa, Hake, Walburga, Hanekamp, Dominik, Bettenworth, Dennis, Mulac, Klaus, Langer, Matthias, Lehr
Publikováno v:
Bioorganicmedicinal chemistry. 77
Indole-5-carboxylic acids with 3-aryloxy-2‑oxopropyl residues in position 1 have been shown to be potent inhibitors of cytosolic phospholipase A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4fa4d1403e20dd406f55e16054085b62
https://pubmed.ncbi.nlm.nih.gov/36495814
https://pubmed.ncbi.nlm.nih.gov/36495814
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 163:212-222
Poly(DL-lactic-co-glycolic acid) and poly(DL-lactic acid) are widely used for the preparation of nanoparticles due to favorable characteristics for medical use like biodegradability and controllable degradation behavior. The contact with different me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b646eba5f47c7cba69f211d09a1ff444
https://doi.org/10.1016/j.ejpb.2021.04.006
https://doi.org/10.1016/j.ejpb.2021.04.006