Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Dennis Miskel"'
Autor:
Jessica Kurzella, Dennis Miskel, Franca Rings, Ernst Tholen, Dawit Tesfaye, Karl Schellander, Dessie Salilew-Wondim, Eva Held-Hoelker, Christine Große-Brinkhaus, Michael Hoelker
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract The major limitation of the widespread use of IVP derived embryos is their consistent deficiencies in vitality when compared with their ex vivo derived counterparts. Although embryo metabolism is considered a useful metric of embryo quality,
Externí odkaz:
https://doaj.org/article/bcf47e3fcacd4081aabf4294ed9d404a
Autor:
Dessie Salilew-Wondim, Ernst Tholen, Eva Held-Hoelker, Karl Shellander, Carina Blaschka, Marc Drillich, Michael Iwersen, David Suess, Samuel Gebremedhn, Dawit Tesfaye, Claudia Parys, Ariane Helmbrecht, Jessie Guyader, Dennis Miskel, Nares Trakooljul, Klaus Wimmers, Michael Hoelker
Publikováno v:
Frontiers in Genetics, Vol 14 (2024)
Post calving metabolic stress reduces the fertility of high producing dairy cows possibly by altering the expression of genes in the maternal environment via epigenetic modifications. Therefore, this study was conducted to identify endometrial DNA me
Externí odkaz:
https://doaj.org/article/85bee0e512fe46b2ab39701602c6780d
Autor:
Dennis Miskel, Mikhael Poirier, Luisa Beunink, Franca Rings, Eva Held, Ernst Tholen, Dawit Tesfaye, Karl Schellander, Dessie Salilew-Wondim, Carina Blaschka, Christine Große-Brinkhaus, Brenig Bertram, Michael Hoelker
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract At the embryonic level, CRISPR technologies have been used to edit genomes reliably and efficiently in various mammalian models, with Ribonucleoprotein (RNP) electroporation potentially representing a superior delivery method into mammalian
Externí odkaz:
https://doaj.org/article/1e1dfcb014f14eaa8c69ecdd82f6d514
Autor:
Dessie Salilew-Wondim, Dawit Tesfaye, Franca Rings, Eva Held-Hoelker, Dennis Miskel, Marc-Andre Sirard, Ernst Tholen, Karl Schellander, Michael Hoelker
Publikováno v:
BMC Genomics, Vol 22, Iss 1, Pp 1-26 (2021)
Abstract Background Morphological evaluation of embryos has been used to screen embryos for transfer. However, the repeatability and accuracy of this method remains low. Thus, evaluation of an embryo’s gene expression signature with respect to its
Externí odkaz:
https://doaj.org/article/8eb5c24468d445e4a5d84a90ff10e0be
Autor:
Dennis Miskel, Mikhael Poirier, Luisa Beunink, Franca Rings, Eva Held, Ernst Tholen, Dawit Tesfaye, Karl Schellander, Dessie Salilew-Wondim, Carina Blaschka, Christine Große-Brinkhaus, Bertram Brenig, Michael Hoelker
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/741ae700014842cda1c7ac5effb01359
Autor:
Antonia Albrecht, Martin Hebel, Céline Heinemann, Ulrike Herbert, Dennis Miskel, Behnam Saremi, Judith Kreyenschmidt
Publikováno v:
Journal of Food Quality, Vol 2019 (2019)
A trial with different concentrations of DL-methionine (DLM) and DL-2-hydroxy-4-methylthiobutanoic acid (DL-HMTBA) in broiler feed was performed to investigate their effect on the meat quality parameters and the shelf life of breast fillet. In total,
Externí odkaz:
https://doaj.org/article/baca7651f21b4730b5e757366b5a708f
Autor:
Dennis Miskel, Mikhael Poirier, Luisa Beunink, Franca Rings, Eva Held, Ernst Tholen, Dawit Tesfaye, Karl Schellander, Dessie Salilew-Wondim, Carina Blaschka, Christine Große-Brinkhaus, Bertram Brenig, Michael Hoelker
Publikováno v:
Scientific reports. 12(1)
At the embryonic level, CRISPR technologies have been used to edit genomes reliably and efficiently in various mammalian models, with Ribonucleoprotein (RNP) electroporation potentially representing a superior delivery method into mammalian zygotes.
Autor:
Ulrike Herbert, Antonia Albrecht, Martin Hebel, Judith Kreyenschmidt, Dennis Miskel, Céline Heinemann, Behnam Saremi
Publikováno v:
Journal of Food Quality, Vol 2019 (2019)
A trial with different concentrations of DL-methionine (DLM) and DL-2-hydroxy-4-methylthiobutanoic acid (DL-HMTBA) in broiler feed was performed to investigate their effect on the meat quality parameters and the shelf life of breast fillet. In total,
Autor:
L. Beunink, Dennis Miskel, F. Rings, Vitezslav Havlicek, Urban Besenfelder, Michael Hölker, Mikhael Poirier, Karl Schellander
Publikováno v:
Reproduction, Fertility and Development. 32:193
In recent years, CRISPR/Cas9 has been used to efficiently edit the genomes of embryos in many animal models. Due to smaller anatomy, lower costs, and multiple ovulations, it is relatively simple to derive large numbers of invivo fertilized zygotes fo
Publikováno v:
Reproduction, Fertility and Development
Successful genome editing of blastocysts using zygote microinjection with transcription activator-like effector nucleases has already been accomplished in cattle as well as a limited number of CRISPR-Cas9 microinjections of zygotes, mostly using RNA.