Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Dennis Milanowski"'
Autor:
Adam Ray, Yao Shi, Michael Van Parys, Dennis Milanowski, Abigail Walker, Brian Dean, Dewakar Sangaraju, Xiaorong Liang, Allan Jaochico, Rachel Caminiti
Publikováno v:
Journal of the American Society for Mass Spectrometry. 32(8)
Bile acids (BAs) are biomolecules synthesized in the liver from cholesterol and are constituents of bile. The in-vivo BA pool includes more than 50 known diverse BAs which are unconjugated, amino acid conjugated, sulfated, and glucuronidated metaboli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4719f9125b0c8a806f0d250c35698d9e
https://pubmed.ncbi.nlm.nih.gov/33826317
https://pubmed.ncbi.nlm.nih.gov/33826317
Autor:
Sami Mahrus, Dennis Milanowski, Kari M. Morrissey, Dennis L. Miller, Brian Dean, Stephanie Cape, Drew Dorshorst, Xiaorong Liang, Janine McKnight, Lei Tan
Publikováno v:
Bioanalysis. 10:1307-1317
Aim: Indoleamine 2,3-dioxygenase (IDO) and tryptophan 2,3-dioxygenase (TDO) catalyze the initial and rate-controlling step of tryptophan metabolism through the kynurenine pathway, which plays an important role in mediating immune response. Accurate m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fb70afddc195e996282f3765d744585
https://doi.org/10.4155/bio-2018-0044
https://doi.org/10.4155/bio-2018-0044
Autor:
Michael Van Parys, Xiaorong Liang, Dennis L. Miller, Brian Dean, Yang Gao, Yao Shi, Dennis Milanowski
Publikováno v:
Bioanalysis. 10:917-932
Aim: Investigation of bile acids (BAs) as biomarkers for liver and kidney diseases has gained momentum recently to fulfill the needs in drug development and clinical practice, but a thorough and rapid profiling of BAs in human plasma has been hindere
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d50deb9d1f860ec16961cfebaf9379a
https://doi.org/10.4155/bio-2018-0018
https://doi.org/10.4155/bio-2018-0018
Autor:
Tracy Staton, Meire Bremer, Stephanie Cape, Yang Gao, Dennis Milanowski, Xiao Ding, Fang Cai, Jianshuang Wang, Brian Dean, Drew Dorshorst
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 133:96-104
In human respiratory disease studies, liquid samples such as nasal secretion (NS), lung epithelial lining fluid (ELF), or upper airway mucosal lining fluid (MLF) are frequently collected, but their volumes often remain unknown. The lack of volume inf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b475ad4b909910335a40e5cf97bdec3
https://doi.org/10.1016/j.jpba.2016.11.001
https://doi.org/10.1016/j.jpba.2016.11.001
Autor:
Xiao Ding, Brian Dean, Yuzhong Deng, Michael Van Parys, Jialin Mao, Ning Zeng, Janine McKnight, Luke Bi, Yuan Chen, Joseph A. Ware, Cornelis E. C. A. Hop, Drew Dorshort, Xiaorong Liang, Dennis Milanowski
Publikováno v:
Journal of Chromatography B. 1020:111-119
A high-performance liquid chromatography tandem mass spectrometry (LC-MS/MS) assay was developed and validated for simultaneous determination of itraconazole (ITZ), hydroxy-itraconazole (OH-ITZ), keto-itraconazole (keto-ITZ) and N-desalkyl itraconazo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4852d7b291d8ce2aaae2ad6db3aeb1dc
https://doi.org/10.1016/j.jchromb.2016.03.039
https://doi.org/10.1016/j.jchromb.2016.03.039
Autor:
Michael Van Parys, Dennis Milanowski, Xiao Ding, Jianshuang Wang, Lin Pan, Janine McKnight, Yuan Chen, Dorothy Cheung, Brian Dean
Publikováno v:
Biomedical Chromatography. 33:e4482
A specific and robust LC-MS/MS method was developed and validated for the quantitative determination of GDC-3280 in human plasma and urine. The nonspecific binding associated with urine samples was overcome by the addition of CHAPS. The sample volume
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3b21d9e1e74bb9d7dfb153270cbf45e
https://doi.org/10.1002/bmc.4482
https://doi.org/10.1002/bmc.4482
Autor:
Min Hu, Snjezana Lelas, Michael Sinz, Yuri L. Khmelnitsky, Dennis Milanowski, Anne Payen-Fornicola, Matthew Isherwood, Dalton King, Nicholas Holman, Carla Hassler, Wenge Cui, Jonathan O’Connell, Yuh-Lin Yang, Ulhas Bhatt, Nicholas J. Lodge, Yu-Wen Li, Roy Haskell, John E. Macor, Sargent Bruce J, Kim A. Johnson, Linda Fleming, Stephen P. Adams, Vadim V. Mozhaev, Sarah M. Ebeltoft, Shuang Liu, Thaddeus F. Molski, Sambandam Aruna, Richard E. Olson, Congxiang Zha, Robert L. Bertekap, Bruce F. Molino, Wendy Clarke, Robert Zaczek, Anthony D. Pechulis, Michael Herr, Peter R. Guzzo, Larry Yet, Alicia Ng, Anitra F. Orie, Ian C. Cotterill, Kassoum Nacro
Publikováno v:
ACS medicinal chemistry letters. 5(7)
A series of 4-bicyclic heteroaryl 1,2,3,4-tetrahydroisoquinoline inhibitors of the serotonin transporter (SERT), norepinephrine transporter (NET), and dopamine transporter (DAT) was discovered. The synthesis and structure-activity relationship (SAR)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2d5735ba509f2dee5e16c0853dacd5b
https://pubmed.ncbi.nlm.nih.gov/25050161
https://pubmed.ncbi.nlm.nih.gov/25050161
Autor:
Jialin Mao, Michael Van Parys, Yuzhong Deng, Xiao Ding, Janine McKnight, Drew Dorshorst, Brian Dean, Joseph A. Ware, Cornelis E. C. A. Hop, Luke Bi, Yuan Chen, Ning Zeng, Dennis Milanowski, Xiaorong Liang
Publikováno v:
Journal of Chromatography B. :239
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92f336171342a8f37bf36b796dea144f
https://doi.org/10.1016/j.jchromb.2016.06.023
https://doi.org/10.1016/j.jchromb.2016.06.023
Publikováno v:
Mutation research. 264(4)
Chinese hamster ovary (CHO-WBLT) cells growing in McCoy's 5a with 10% fetal bovine serum (FBS) were adapted to 0.5% FBS in CHO-1 Complete Media System, a serum-free medium from Ventrex. Cells in these two media were exposed to 10−7 M and 10−8 M m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5092f905752703dca78de0c257bbcea8
https://pubmed.ncbi.nlm.nih.gov/1723496
https://pubmed.ncbi.nlm.nih.gov/1723496