Pathologic and phenotypic alterations in a mouse expressing a connexin47 missense mutation that causes Pelizaeus-Merzbacher-like disease in humans.

Autor: Oliver Tress, Marta Maglione, Armin Zlomuzica, Dennis May, Nikolai Dicke, Joachim Degen, Ekrem Dere, Helmut Kettenmann, Dieter Hartmann, Klaus Willecke

Publikováno v: PLoS Genetics, Vol 7, Iss 7, p e1002146 (2011)

Gap junction channels are intercellular conduits that allow diffusional exchange of ions, second messengers, and metabolites. Human oligodendrocytes express the gap junction protein connexin47 (Cx47), which is encoded by the GJC2 gene. The autosomal

Externí odkaz: https://doaj.org/article/8c5580de9b074600841a02b4205d381a

Author response: Live imaging reveals chromatin compaction transitions and dynamic transcriptional bursting during stem cell differentiation in vivo

Autor: Sangwon Yun, Dennis May, David G Gonzalez, Sangbum Park, Yanbo Chen, Elizabeth Lathrop, Biao Cai, Tianchi Xin, Hongyu Zhao, Siyuan Wang, Lauren E Gonzalez, Katie Cockburn, Valentina Greco

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e7861fc0f3d154c900205bd8d17f2893
https://doi.org/10.7554/elife.83444.sa2

Skin-resident immune cells actively coordinate their distribution with epidermal cells during homeostasis

Autor: Olga Markova, David Gonzalez, Edward Marsh, Elizabeth A. Lathrop, Sang-Bum Park, Yohanns Bellaïche, Jessica L. Moore, Axel Schmitter-Sánchez, Cristiana M. Pineda, Jonathan D. Boucher, Katie Cockburn, Valentina Greco, Dennis May, Catherine Matte-Martone

Publikováno v: Nature Cell Biology
Nature Cell Biology, Nature Publishing Group, 2021, ⟨10.1038/s41556-021-00670-5⟩
Nature Cell Biology, 2021, ⟨10.1038/s41556-021-00670-5⟩

International audience; Organs consist of multiple cell types that ensure proper architecture and function. How different cell types coexist and interact to maintain their homeostasis in vivo remains elusive. The skin epidermis comprises mostly epith

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db64d59379c128552339452ed8714105
https://hal.archives-ouvertes.fr/hal-03452763

3D super-resolution deep-tissue imaging in living mice

Autor: Martin J. Booth, Valentina Greco, Mary Grace M. Velasco, Jacopo Antonello, Edward S. Allgeyer, Dennis May, Ons M’Saad, Andrew E.S. Barentine, Peng Yuan, Jaime Grutzendler, Joerg Bewersdorf, Mengyang Zhang, Phylicia Kidd

Publikováno v: Optica
bioRxiv

Stimulated emission depletion (STED) microscopy enables the three-dimensional (3D) visualization of dynamic nanoscale structures in living cells, offering unique insights into their organization. However, 3D-STED imaging deep inside biological tissue

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62c0d0b167e7128fb12ec0636da4363e
https://pubmed.ncbi.nlm.nih.gov/34239948

Connexin47 Protein Phosphorylation and Stability in Oligodendrocytes Depend on Expression of Connexin43 Protein in Astrocytes

Autor: Klaus Willecke, Gerald Seifert, Oliver Tress, Dennis May

Publikováno v: Journal of Neuroscience; Vol 33

Panglial networks are essential for normal physiology in the CNS, and the function of distinct connexins participating in these networks is not well understood. We generated Connexin32 (Cx32)-deficient mice with additional deletion of astrocytic Cx43

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77e1015cb1a67bb33f846d8e4b2a91b5