Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Dennis M. Minton"'
Autor:
Dennis M. Minton, Christian J. Elliehausen, Martin A. Javors, Kelly S. Santangello, Adam R. Konopka
Publikováno v:
Arthritis Research & Therapy, Vol 23, Iss 1, Pp 1-14 (2021)
Abstract Background The objective of this study was to determine if mechanistic target of rapamycin (mTOR) inhibition with or without AMP-activated protein kinase (AMPK) activation can protect against primary, age-related OA. Design Dunkin-Hartley gu
Externí odkaz:
https://doaj.org/article/daa2a283515e4fd284e082004e71767e
Autor:
William D. Fairfield, Dennis M. Minton, Christian J. Elliehausen, Alexander D. Nichol, Taylor L. Cook, John A. Rathmacher, Lisa M. Pitchford, Scott A. Paluska, Adam J. Kuchnia, Jacob M. Allen, Adam R. Konopka
Publikováno v:
Nutrients, Vol 14, Iss 21, p 4674 (2022)
β-Hydroxy-β-methylbutyrate (HMB), a leucine metabolite, can increase skeletal muscle size and function. However, HMB may be less effective at improving muscle function in people with insufficient Vitamin D3 (25-OH-D < 30 ng/mL) which is common in m
Externí odkaz:
https://doaj.org/article/f3a738a884184437b31e87a2397628a3
Autor:
Dennis M. Minton, Christian J. Elliehausen, Martin A. Javors, Kelly S. Santangelo, Adam R. Konopka
Publikováno v:
Arthritis Research & Therapy, Vol 24, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/693ef9745a2447b6a34c3b6b410e2075
Autor:
Christian J. Elliehausen, William D. Fairfield, Dennis M. Minton, Alex D. Nichol, John A. Rathmacher, Lisa M. Pitchford, Scott A. Paluska, Jacob M. Allen, Adam R. Konopka
Publikováno v:
The FASEB Journal. 36
Autor:
Martin A. Javors, Adam R. Konopka, Dennis M. Minton, Kelly S. Santangello, Christian J. Elliehausen
Publikováno v:
Arthritis Research & Therapy
Arthritis Research & Therapy, Vol 23, Iss 1, Pp 1-14 (2021)
Arthritis Research & Therapy, Vol 23, Iss 1, Pp 1-14 (2021)
Background The objective of this study was to determine if mechanistic target of rapamycin (mTOR) inhibition with or without AMP-activated protein kinase (AMPK) activation can protect against primary, age-related OA. Design Dunkin-Hartley guinea pigs
Publikováno v:
Exp Gerontol
A decline in skeletal muscle mitochondrial function is associated with the loss of skeletal muscle size and function during knee osteoarthritis (OA). We have recently reported that the 12-weeks of dietary rapamycin (Rap, 14ppm), with or without metfo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3ef4fb30ee85a0964cbf8201cb5e51e
https://europepmc.org/articles/PMC8560569/
https://europepmc.org/articles/PMC8560569/
Publikováno v:
The FASEB Journal. 35
Publikováno v:
Osteoarthritis and Cartilage. 29:S102-S103
Publikováno v:
Innovation in Aging
Age is a primary risk factor for osteoarthritis (OA). The mechanisms that contribute to OA are poorly understood and disease modifying treatments have not been identified. A critical shortcoming in developing therapies is the limited number of transl