Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Dennis M L Langenberg"'
Autor:
Gerben Ferwerda, Stephen E Girardin, Bart-Jan Kullberg, Lionel Le Bourhis, Dirk J de Jong, Dennis M L Langenberg, Reinout van Crevel, Gosse J Adema, Tom H M Ottenhoff, Jos W M Van der Meer, Mihai G Netea
Publikováno v:
PLoS Pathogens, Vol 1, Iss 3, Pp 279-285 (2005)
Infection with Mycobacterium tuberculosis is one of the leading causes of death worldwide. Recognition of M. tuberculosis by pattern recognition receptors is crucial for activation of both innate and adaptive immune responses. In the present study, w
Externí odkaz:
https://doaj.org/article/6488f73434ec4f34b39dffefb812df9c
Autor:
Abraham J. Koster, Arie J. Verkleij, Jean-Luc A. N. Murk, Hans J. Geuze, Dennis M. L. Langenberg, Janice Griffith, Frank A. W. Verreck, Monique J. Kleijmeer, Bruno M. Humbel, Willie J. C. Geerts, M.N. Lebbink
Publikováno v:
Traffic. 5:936-945
In late endosomes and lysosomes of antigen presenting cells major histocompatibility complex class II (MHC II) molecules bind peptides from degraded internalized pathogens. These compartments are called MHC class II compartments (MIICs), and from her
Autor:
Josephine C. Dorsman, R. A. C. Roos, Gert-Jan B. van Ommen, Dennis M. L. Langenberg, Henri Kerkdijk, Johan T. den Dunnen, Barry A. Pepers, Marije Ijszenga
Publikováno v:
Human Molecular Genetics. 11:1487-1496
Expansion of a Glutamine (Gln) repeat above a specific critical size in certain proteins gives rise to aggregation-prone proteins that cause neurodegenerative disorders, such as Huntington's disease. However, proteins with long hydrophilic polyglutam
Autor:
Reinout van Crevel, Jos W. M. van der Meer, Bart Jan Kullberg, Dennis M. L. Langenberg, Tom H. M. Ottenhoff, Gerben Ferwerda, Mihai G. Netea, Stephen E. Girardin, Dirk J. de Jong
Publikováno v:
Journal of Leukocyte Biology, 82, 4, pp. 1011-8
Journal of Leukocyte Biology, 82, 1011-8
Journal of Leukocyte Biology, 82, 1011-8
Contains fulltext : 53634.pdf (Publisher’s version ) (Open Access) Mycobacterium paratuberculosis has been suggested to be involved in the pathogenesis of Crohn's disease (CD). The importance of microorganisms in CD is supported by the association
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66ada4dfd088fa11cd2865ac5336a31b
https://hdl.handle.net/https://repository.ubn.ru.nl/handle/2066/53634
https://hdl.handle.net/https://repository.ubn.ru.nl/handle/2066/53634
Autor:
Rene De Waal Malefyt, Frank A. W. Verreck, Dennis M. L. Langenberg, Marieke A. Hoeve, Tom H. M. Ottenhoff, Tjitske de Boer, Nigel D. L. Savage
Publikováno v:
European journal of immunology. 36(3)
IL-23 is regarded as a major pro-inflammatory mediator in autoimmune disease, a role which until recently was ascribed to its related cytokine IL-12. IL-23, an IL-12p40/p19 heterodimeric protein, binds to IL-12Rbeta1/IL-23R receptor complexes. Mice d
Autor:
Jos W. M. van der Meer, Dennis M. L. Langenberg, Bart Jan Kullberg, Stephen E. Girardin, Gerben Ferwerda, Lionel Le Bourhis, Mihai G. Netea, Tom H. M. Ottenhoff, Gosse J. Adema, Dirk J. de Jong, Reinout van Crevel
Publikováno v:
Plos Pathogens, 1, 3, pp. 279-85
PLoS Pathogens
Plos Pathogens, 1, 279-85
PLoS Pathogens, 2005, 1, pp.279-85. ⟨10.1371/journal.ppat.0010034⟩
PLoS Pathogens, Public Library of Science, 2005, 1, pp.279-85. ⟨10.1371/journal.ppat.0010034⟩
PLoS Pathogens, Vol 1, Iss 3, Pp 279-285 (2005)
PLoS Pathogens
Plos Pathogens, 1, 279-85
PLoS Pathogens, 2005, 1, pp.279-85. ⟨10.1371/journal.ppat.0010034⟩
PLoS Pathogens, Public Library of Science, 2005, 1, pp.279-85. ⟨10.1371/journal.ppat.0010034⟩
PLoS Pathogens, Vol 1, Iss 3, Pp 279-285 (2005)
Infection with Mycobacterium tuberculosis is one of the leading causes of death worldwide. Recognition of M. tuberculosis by pattern recognition receptors is crucial for activation of both innate and adaptive immune responses. In the present study, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c59f3301e9bc5a296915f64dcfeb51a
https://hdl.handle.net/2066/48910
https://hdl.handle.net/2066/48910
Autor:
Jean-Luc A N, Murk, Misjaël N, Lebbink, Bruno M, Humbel, Willie J C, Geerts, Janice M, Griffith, Dennis M L, Langenberg, Frank A W, Verreck, Arie J, Verkleij, Abraham J, Koster, Hans J, Geuze, Monique J, Kleijmeer
Publikováno v:
Traffic (Copenhagen, Denmark). 5(12)
In late endosomes and lysosomes of antigen presenting cells major histocompatibility complex class II (MHC II) molecules bind peptides from degraded internalized pathogens. These compartments are called MHC class II compartments (MIICs), and from her
Autor:
Tjitske de Boer, Robert A. Kastelein, Elena Vaisberg, Rene de Waal-Malefyt, Frank A. W. Verreck, Matthijs Kramer, Dennis M. L. Langenberg, Arend J. Kolk, Tom H. M. Ottenhoff, Marieke A. Hoeve
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 101(13), 4560-4565. National Academy of Sciences
Proceedings of the National Academy of Sciences USA, 101, 13, pp. 4560-5
Proceedings of the National Academy of Sciences USA, 101, 4560-5
Proceedings of the National Academy of Sciences USA, 101, 13, pp. 4560-5
Proceedings of the National Academy of Sciences USA, 101, 4560-5
Contains fulltext : 58278.pdf (Publisher’s version ) (Closed access) Macrophages (Mphi) play a central role as effector cells in immunity to intracellular pathogens such as Mycobacterium. Paradoxically, they also provide a habitat for intracellular
Autor:
Frank A. W. Verreck, Dennis M. L. Langenberg, Ozden Sanal, Marieke A. Hoeve, Tom H. M. Ottenhoff, Tjitske de Boer
Publikováno v:
European journal of immunology. 33(12)
IFN-gamma and IL-12 are crucial cytokines for cell-mediated immunity against intracellular pathogens. We have previously shown that human IL-12Rbeta1-deficiency leads to impaired IL-12 responsiveness and unusual susceptibility to infections due to my
Autor:
Mihai G. Netea, Xianzhong Meng, Charles A. Dinarello, Leo A. B. Joosten, Maorong Wang, Dennis M. L. Langenberg, Eli C. Lewis, Tania Azam, Tom H. M. Ottenhoff, Do-Young Yoon, Soohyun Kim, Edward D. Chan
Publikováno v:
PLoS Medicine
PLoS Medicine, Vol 3, Iss 8, p e277 (2006)
Plos Medicine, 3, 8, pp. 1310-9
Plos Medicine, 3, 1310-9
PLoS Medicine, Vol 3, Iss 8, p e277 (2006)
Plos Medicine, 3, 8, pp. 1310-9
Plos Medicine, 3, 1310-9
Background Interleukin (IL)–32 is a newly described proinflammatory cytokine that seems likely to play a role in inflammation and host defense. Little is known about the regulation of IL-32 production by primary cells of the immune system. Methods