Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Dennis M, Abraham"'
Autor:
Muath Bishawi, Franklin H. Lee, Dennis M. Abraham, Carolyn Glass, Stephanie J. Blocker, Daniel J. Cox, Zachary D. Brown, Howard A. Rockman, Lan Mao, Tony C. Slaba, Mark W. Dewhirst, George A. Truskey, Dawn E. Bowles
Publikováno v:
iScience, Vol 25, Iss 4, Pp 104086- (2022)
Summary: The complex and inaccessible space radiation environment poses an unresolved risk to astronaut cardiovascular health during long-term space exploration missions. To model this risk, healthy male c57BL/6 mice aged six months (corresponding to
Externí odkaz:
https://doaj.org/article/43a2ac87251e41e4a3c21bafd33ba469
Autor:
Johannes Stegbauer, Fitra Rianto, Subramaniam Pennathur, Steven D. Crowley, Dennis M. Abraham, Matthew A. Sparks, Phillip Ruiz, Susan B. Gurley, Edward J. Diaz, Thomas M. Coffman, Thien A. Hoang, Anuradha Vivekanandan-Giri, Ritika Revoori, Lucas Bouknight
Publikováno v:
Hypertension. 77:393-404
Activation of AT 1 (type 1 Ang) receptors stimulates cardiomyocyte hypertrophy in vitro. Accordingly, it has been suggested that regression of cardiac hypertrophy associated with renin-Ang system blockade is due to inhibition of cellular actions of A
Autor:
Deborah M. Muoio, Timothy R. Koves, James A. Draper, Tara M. Narowski, Kelsey H. Fisher-Wellman, Ling Lai, Michael T. Davidson, Dennis M. Abraham, Daniel P. Kelly, Paul A. Grimsrud
Publikováno v:
Circ Res
Rationale: Circumstantial evidence links the development of heart failure to posttranslational modifications of mitochondrial proteins, including lysine acetylation (Kac). Nonetheless, direct evidence that Kac compromises mitochondrial performance re
Autor:
Sudarshan Rajagopal, Myles Wolf, Linda K. Shaw, Dennis M. Abraham, Matthew A. Sparks, Kishan S. Parikh, Daniel L. Edmonston, Alexander Grabner
Publikováno v:
American Journal of Kidney Diseases. 75:713-724
Rationale & Objective Pulmonary hypertension (PH) contributes to cardiovascular disease and mortality in patients with chronic kidney disease (CKD), but the pathophysiology is mostly unknown. This study sought to estimate the prevalence and consequen
Publikováno v:
Am J Physiol Heart Circ Physiol
Tandem pore domain acid-sensitive K+ (TASK) channels are present in cardiac tissue; however, their contribution to cardiac pathophysiology is not well understood. Here, we investigate the role of TASK-1 and TASK-3 in the pathogenesis of cardiac dysfu
Autor:
Sang-oh Han, Priya S. Kishnani, Alexina C. Haynes, Richard Steet, Songtao Li, Dennis M. Abraham, Dwight D. Koeberl
Publikováno v:
Mol Genet Metab
Pompe disease is caused by the deficiency of lysosomal acid α-glucosidase (GAA) leading to progressive myopathy. Enzyme replacement therapy (ERT) with recombinant human (rh) GAA has limitations, including inefficient uptake of rhGAA in skeletal musc
Autor:
Muath Bishawi, Franklin H. Lee, Dennis M. Abraham, Carolyn Glass, Stephanie J. Blocker, Daniel J. Cox, Zachary D. Brown, Howard A. Rockman, Lan Mao, Tony C. Slaba, Mark W. Dewhirst, George A. Truskey, Dawn E. Bowles
Publikováno v:
iScience. 25(4)
The complex and inaccessible space radiation environment poses an unresolved risk to astronaut cardiovascular health during long-term space exploration missions. To model this risk, healthy male c57BL/6 mice aged six months (corresponding to an astro
Autor:
Dennis M. Abraham, Howard A. Rockman, Sudha K. Shenoy, Lan Mao, Clarice Gareri, Suneet Kaur, Samuel Mon-Wei Yu, Pierre-Yves Jean-Charles
Publikováno v:
Journal of Biological Chemistry. 294:2500-2518
Reversible ubiquitination of G protein–coupled receptors regulates their trafficking and signaling; whether deubiquitinases regulate myocardial β1-adrenergic receptors (β1ARs) is unknown. We report that ubiquitin-specific protease 20 (USP20) deub
Autor:
Janet L. Huebner, James P. White, David E Lee, William E. Kraus, Kim M. Huffman, Akshay Bareja, Brian J. Andonian, Lauren H. Katz, Dennis M. Abraham
Publikováno v:
J Appl Physiol (1985)
Rheumatoid arthritis (RA) is a systemic inflammatory arthritis impacting primarily joints and cardiac and skeletal muscle. RA’s distinct impact on cardiac and skeletal muscle tissue is suggested by studies showing that new RA pharmacologic agents s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fbcd99ae242ad54e3e4eee53e2d5971
https://europepmc.org/articles/PMC7988790/
https://europepmc.org/articles/PMC7988790/
Autor:
Matthew A, Sparks, Fitra, Rianto, Edward, Diaz, Ritika, Revoori, Thien, Hoang, Lucas, Bouknight, Johannes, Stegbauer, Anuradha, Vivekanandan-Giri, Phillip, Ruiz, Subramaniam, Pennathur, Dennis M, Abraham, Susan B, Gurley, Steven D, Crowley, Thomas M, Coffman
Publikováno v:
Hypertension (Dallas, Tex. : 1979)
Supplemental Digital Content is available in the text.
Activation of AT1 (type 1 Ang) receptors stimulates cardiomyocyte hypertrophy in vitro. Accordingly, it has been suggested that regression of cardiac hypertrophy associated with renin-Ang sy
Activation of AT1 (type 1 Ang) receptors stimulates cardiomyocyte hypertrophy in vitro. Accordingly, it has been suggested that regression of cardiac hypertrophy associated with renin-Ang sy