Conserved Role of the Large Conductance Calcium-Activated Potassium Channel, K Ca 1.1, in Sinus Node Function and Arrhythmia Risk

Autor: Georg Vogler, Diane Fatkin, Katja Birker, Christiana Leimena, Ann-Kristin Altekoester, Peter C. M. Molenaar, Karen Ocorr, David G. Allen, Richard P. Harvey, Halina Dobrzynski, Inken G. Huttner, Arie Jacoby, Magdalena Soka, Renee Johnson, Andrew Atkinson, Vesna Nikolova-Krstevski, Adam P. Hill, Rolf Bodmer, Yue-Kun Ju, Sreehari Kalvakuri, Santiago Pineda, Dirk F. van Helden, Charles D. Cox, Dennis L. Kuchar, Monique Ohanian, Gunjan Trivedi

Publikováno v: Circulation: Genomic and Precision Medicine. 14

Background: KCNMA1 encodes the α-subunit of the large-conductance Ca 2+ -activated K + channel, K Ca 1.1, and lies within a linkage interval for atrial fibrillation (AF). Insights into the cardiac functions of K Ca 1.1 are limited, and KCNMA1 has no

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01612d0422981dad9c335de2df839668
https://doi.org/10.1161/circgen.120.003144

The electrocardiogram in ischaemic heart disease

Autor: Dennis L. Kuchar, Geoffrey S. Oldfield

Publikováno v: Interventional Cardiology and Cardiac Catheterisation ISBN: 9781351060356
Cardiology and Cardiac Catheterisation: The Essential Guide

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6555638de60c5a3511215f0a21ba4696
https://doi.org/10.1201/9781351060356-19

Impact of Implantable Cardioverter Defibrillators on Survival of Patients with Centrifugal Left Ventricular Assist Devices

Autor: Peter S. Macdonald, Andrew Jabbour, Kumud Dhital, Eugene Kotlyar, Emily Granger, Paul Jansz, William Lee, Andre Tay, Bruce D. Walker, Anne Keogh, Rajesh N. Subbiah, Dennis L. Kuchar, Philip Spratt, Kavitha Muthiah, Christopher S. Hayward

Publikováno v: Pacing and Clinical Electrophysiology. 38:925-933

Background Both implantable cardioverter defibrillators (ICDs) and left ventricular assist devices (LVADs) have a positive impact on survival in the heart failure population. We sought to determine whether these positive effects on survival are addit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ff5e48c0b5ad21fbc55de85d09b6490f
https://doi.org/10.1111/pace.12654

Permanent Pacing for Late-Onset Atrioventricular Block in Patients with Heart Transplantation: A Single Center Experience

Autor: Emily Granger, E R N Andre Tay, Anne Keogh, Paul Jansz, Alan Farnsworth, Eugene Kotlyar, Peter S. Macdonald, Chris Hayward, S.C. Faddy, Phillip Spratt, Sern Lim, Bruce D. Walker, Charles W. Thorburn, Rajesh N. Subbiah, Dennis L. Kuchar

Publikováno v: Pacing and Clinical Electrophysiology. 34:72-75

INTRODUCTION: The incidence, mechanisms, clinical associations, and outcomes in patients with late-onset (>3 months) atrioventricular (AV) block following heart transplantation are not well known. This study will characterize late-onset AV block foll

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3b2772168caeb76aa69f5e1db4717e87
https://doi.org/10.1111/j.1540-8159.2010.02906.x

Accelerated graft dysfunction in heart transplant patients with persistent atrioventricular conduction block

Autor: William Lee, Rajesh N. Subbiah, Dennis L. Kuchar, Phillip Spratt, Christopher S. Hayward, Bruce D. Walker, Andre Tay

Publikováno v: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology. 18(12)

Aims Bradyarrhythmia following heart transplantation is common—∼7.5–24% of patients require permanent pacemaker (PPM) implantation. While overall mortality is similar to their non-paced counterparts, the effects of chronic right ventricular pac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a142554b1e9765e0aa84f8b67ff25fe4
https://pubmed.ncbi.nlm.nih.gov/26847073