Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Dennis Klug"'
Publikováno v:
Malaria Journal, Vol 23, Iss 1, Pp 1-15 (2024)
Abstract The use of fluorescent proteins (FPs) in Plasmodium parasites has been key to understand the biology of this obligate intracellular protozoon. FPs like the green fluorescent protein (GFP) enabled to explore protein localization, promoter act
Externí odkaz:
https://doaj.org/article/b2b359d88d3342089b6ac1f234c2793f
Autor:
Emily I Green, Etienne Jaouen, Dennis Klug, Roenick Proveti Olmo, Amandine Gautier, Stéphanie Blandin, Eric Marois
Publikováno v:
eLife, Vol 12 (2023)
Lipophorin is an essential, highly expressed lipid transport protein that is secreted and circulates in insect hemolymph. We hijacked the Anopheles coluzzii Lipophorin gene to make it co-express a single-chain version of antibody 2A10, which binds sp
Externí odkaz:
https://doaj.org/article/620212f393c14129ac8d4d02d828899c
Publikováno v:
PLoS Pathogens, Vol 19, Iss 3, p e1010538 (2023)
Malaria is caused by the unicellular parasite Plasmodium which is transmitted to humans through the bite of infected female Anopheles mosquitoes. To initiate sexual reproduction and to infect the midgut of the mosquito, Plasmodium gametocytes are abl
Externí odkaz:
https://doaj.org/article/465671acfdc1462db5a46676c7da0b5f
Autor:
Konrad Beyer, Simon Kracht, Jessica Kehrer, Mirko Singer, Dennis Klug, Friedrich Frischknecht
Publikováno v:
Malaria Journal, Vol 20, Iss 1, Pp 1-12 (2021)
Abstract Background Plasmodium sporozoites are the highly motile forms of malaria-causing parasites that are transmitted by the mosquito to the vertebrate host. Sporozoites need to enter and cross several cellular and tissue barriers for which they e
Externí odkaz:
https://doaj.org/article/2050cfbe2e22467882b6624149238cf9
Publikováno v:
PLoS Pathogens, Vol 18, Iss 10 (2022)
Mosquito saliva is a vehicle for the transmission of vector borne pathogens such as Plasmodium parasites and different arboviruses. Despite the key role of the salivary glands in the process of disease transmission, knowledge of host-pathogen interac
Externí odkaz:
https://doaj.org/article/e9866ec416594bcf981d778697fe6b31
Autor:
Dennis Klug, Sarah Goellner, Jessica Kehrer, Julia Sattler, Léanne Strauss, Mirko Singer, Chafen Lu, Timothy A Springer, Friedrich Frischknecht
Publikováno v:
eLife, Vol 9 (2020)
Inserted (I) domains function as ligand-binding domains in adhesins that support cell adhesion and migration in many eukaryotic phyla. These adhesins include integrin αβ heterodimers in metazoans and single subunit transmembrane proteins in apicomp
Externí odkaz:
https://doaj.org/article/d586dc10aeb04760852dd197df2c9446
Autor:
Dennis Klug, Friedrich Frischknecht
Publikováno v:
eLife, Vol 6 (2017)
Malaria is transmitted when an infected Anopheles mosquito deposits Plasmodium sporozoites in the skin during a bite. Sporozoites are formed within oocysts at the mosquito midgut wall and are released into the hemolymph, from where they invade the sa
Externí odkaz:
https://doaj.org/article/d4c36fac46f6472289daacb869ee89b0
Autor:
Kartik S Bane, Simone Lepper, Jessica Kehrer, Julia M Sattler, Mirko Singer, Miriam Reinig, Dennis Klug, Kirsten Heiss, Jake Baum, Ann-Kristin Mueller, Friedrich Frischknecht
Publikováno v:
PLoS Pathogens, Vol 12, Iss 7, p e1005710 (2016)
Parasites causing malaria need to migrate in order to penetrate tissue barriers and enter host cells. Here we show that the actin filament-binding protein coronin regulates gliding motility in Plasmodium berghei sporozoites, the highly motile forms o
Externí odkaz:
https://doaj.org/article/4dedf6d7420c4c4fafc10a887f9ad6ff
Publikováno v:
Open Biology, Vol 6, Iss 4 (2016)
Myzozoans (which include dinoflagellates, chromerids and apicomplexans) display notable divergence from their ciliate sister group, including a reduced mitochondrial genome and divergent metabolic processes. The factors contributing to these divergen
Externí odkaz:
https://doaj.org/article/0bef456f37c84f87b66cc7109b08b460
Autor:
Dennis Klug, Stephanie A Blandin
Publikováno v:
Current Opinion in Microbiology
Current Opinion in Microbiology, 2023, 72, pp.102280. ⟨10.1016/j.mib.2023.102280⟩
Current Opinion in Microbiology, 2023, 72, pp.102280. ⟨10.1016/j.mib.2023.102280⟩
International audience; During their development in mosquitoes, malaria parasites undergo massive losses that are in part due to a potent antiparasitic response mounted by the vector. The most efficient and best-characterized response relies on a com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73750ea2b5190e820ba552c056671894
https://hal.science/hal-04017092/file/islandora_160245.pdf
https://hal.science/hal-04017092/file/islandora_160245.pdf