Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Dennis Juarez"'
Autor:
Pei-Yu Kao, Evangeline Green, Catalina Pereira, Shauna Ekimura, Dennis Juarez, Travis Whyte, Taylor Arhar, Bianca Malaspina, Luiza A. Nogaj, David A. Moffet
Publikováno v:
Journal of Functional Foods, Vol 12, Iss , Pp 450-457 (2015)
The aggregation of the 37-amino acid polypeptide islet amyloid polypeptide (IAPP, amylin), as either insoluble amyloid or as small oligomers, appears to play a direct role in the death of pancreatic β-islet cells in type 2 diabetes. It is believed t
Externí odkaz:
https://doaj.org/article/909d2d234be742d693d807ee54140a27
Autor:
Dennis Juarez, David A. Fruman
Publikováno v:
Trends Cancer
Trends in cancer, vol 7, iss 6
Trends in cancer, vol 7, iss 6
The mevalonate synthesis inhibitors, statins, are mainstay therapeutics for cholesterol management and cardiovascular health. Thirty years of research have uncovered supportive roles for the mevalonate pathway in numerous cellular processes that supp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af7fc7c83b07882a9cb6c8c8af4ef841
https://europepmc.org/articles/PMC8137523/
https://europepmc.org/articles/PMC8137523/
Autor:
Dennis Juarez, David A. Moffet, Bianca Malaspina, Travis Whyte, Catalina Pereira, Evangeline Green, Pei-Yu Kao, Luiza A. Nogaj, Taylor Arhar, Shauna Ekimura
Publikováno v:
Journal of Functional Foods, Vol 12, Iss, Pp 450-457 (2015)
The aggregation of the 37-amino acid polypeptide islet amyloid polypeptide (IAPP, amylin), as either insoluble amyloid or as small oligomers, appears to play a direct role in the death of pancreatic β-islet cells in type 2 diabetes. It is believed t
Autor:
Andrew W. Roberts, Dennis Juarez, Thanh Trang T. Vo, Matthew S. Davids, John R. Hanna, Ahmed Salem, Sharmila Mallya, Lloyd T. Lam, David A. Fruman, Susan O'Brien, Richard J. Bellin, Shruti Bhatt, Jia Jia, Anthony Letai, Suresh Agarwal, Jonathan H. Schatz, Tu Xu, Lee-or Herzog, Joel D. Leverson, Lingxiao Li, Angela G. Fleischman, J. Scott Lee
Publikováno v:
Science translational medicine. 10(445)
Statins have shown promise as anticancer agents in experimental and epidemiologic research. However, any benefit that they provide is likely context-dependent, for example, applicable only to certain cancers or in combination with specific anticancer
Publikováno v:
Blood. 134:4413-4413
The BCL-2 inhibitor venetoclax has begun to change the landscape of therapy for diverse blood cancers. Combining venetoclax with standard of care agents has led to impressive response rates, and increased depth and durability of response compared to
Autor:
Luiza A. Nogaj, Taylor Arhar, Shauna Ekimura, Evangeline Green, Travis Whyte, Dennis Juarez, Bianca Malaspina, David A. Moffet, Pei-Yu Kao, Catalina Pereira
Publikováno v:
The FASEB Journal. 29
Publikováno v:
Cancer Research. 73:A64-A64
Metastasis of breast cancer to the brain is increasing and is a significant cause of morbidity and mortality for breast cancer patients. In order to understand the molecular mechanisms controlling metastasis to the brain, we have generated two mouse