Zobrazeno 1 - 10 of 70 pro vyhledávání: '"Dennis Jine Yuan Hsieh"'
1
Akademický článek
MicroRNA-376a-3p sensitizes CPT-11-resistant colorectal cancer by enhancing apoptosis and reversing the epithelial-to-mesenchymal transition (EMT) through the IGF1R/PI3K/AKT pathway
Autor: Chikondi Jassi, Wei-Wen Kuo, Yu-Chun Chang, Tso-Fu Wang, Tsung-Jung Ho, Dennis Jine-Yuan Hsieh, Chia-Hua Kuo, Ming-Cheng Chen, Chi-Cheng Li, Chih-Yang Huang
Publikováno v: Translational Oncology, Vol 50, Iss , Pp 102125- (2024)
Colorectal cancer (CRC) remains the third most prevalent type of cancer worldwide contributing to an estimated 10 % of all cancer cases. CPT-11 is one of the first-line drugs for CRC treatment. Unfortunately, the development of drug resistance signif
Externí odkaz: https://doaj.org/article/850bcceff1194c6db247510ebf2b0431
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2
Akademický článek
Diallyl trisulfide (DATS) ameliorates cardiac fibrosis in a rat model of diabetes
Autor: Dennis Jine-Yuan Hsieh, Shang-Chuan Ng, Shang-Yeh Lu, Yen-Tun Chiu, Kuan-Ho Lin, Yueh-Min Lin, Chih-Yang Huang, Wei-Wen Kuo
Publikováno v: Journal of Functional Foods, Vol 111, Iss , Pp 105901- (2023)
Cardiac fibrosis is a prevalent pathological complication observed in individuals with diabetes. Diallyl trisulfide (DATS), a bioactive compound found in garlic oil, has been reported to exhibit anti-inflammatory and anti-apoptotic effects in various
Externí odkaz: https://doaj.org/article/ef4172a961aa40c1929b02fe526943eb
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3
Akademický článek
Alcoholic Hericium erinaceus mycelia extract induces SIRT-1/ERK-1/2 mediated autophagy to prevent accumulation and spreading of alpha-synuclein and amyloid-beta peptide on the A53T transgenic mice
Autor: Yu-Jung Lin, Chih-Yang Huang, Bruce Chi-Kang Tsai, Kannan Ashok Kumar, Dennis Jine-Yuan Hsieh, Ping-Ling Chiu, Yung-Ming Chang, Tsung-Jung Ho, Wei-Wen Kuo, Da-Tong Ju
Publikováno v: Journal of Functional Foods, Vol 110, Iss , Pp 105874- (2023)
Alpha-synuclein (α-syn) and amyloid-beta peptide (Aβ) accumulation cause neurodegenerative diseases. The accumulation of neurotoxins, like Aβ, tau, and α-syn is related to aging therefore studying aging mediated neurodegenerative disease is impor
Externí odkaz: https://doaj.org/article/66c717f01e644688b4078fda7f84fa97
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4
Akademický článek
Calycosin inhibits gemcitabine-resistant lung cancer cells proliferation through modulation of the LDOC1/GNL3L/NFκB
Autor: Chi-Cheng Li, Cheng-You Lu, Chiung-Hung Hsu, Dennis Jine-Yuan Hsieh, Tso-Fu Wang, Tsung-Jung Ho, Wei-Wen Kuo, Cecilia Hsuan Day, Shih-Chieh Liao, Ming-Cheng Chen, Chih-Yang Huang
Publikováno v: Chinese Journal of Physiology, Vol 66, Iss 4, Pp 189-199 (2023)
Lung cancer is the most common malignant cancer worldwide. Combination therapies are urgently needed to increase patient survival. Calycosin is a phytoestrogen isoflavone that has been reported previously to inhibit tumor cell growth, although its ef
Externí odkaz: https://doaj.org/article/b3520e7a0b044906864302d877069fa3
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8
Akademický článek
The soybean bioactive peptide VHVV alleviates hypertension-induced renal damage in hypertensive rats via the SIRT1-PGC1α/Nrf2 pathway
Autor: Bruce Chi-Kang Tsai, Wei-Wen Kuo, Cecilia Hsuan Day, Dennis Jine-Yuan Hsieh, Chia-Hua Kuo, Jayasimharayalu Daddam, Ray-Jade Chen, V. Vijaya Padma, Guiqing Wang, Chih-Yang Huang
Publikováno v: Journal of Functional Foods, Vol 75, Iss , Pp 104255- (2020)
Hypertension triggers oxidative stress, causing dysfunction in organs, including the brain, heart, and kidney. In this study, we examined the potential renal benefit of the soybean bioactive peptide VHVV by in silico analysis and in spontaneously hyp
Externí odkaz: https://doaj.org/article/1e8b129fa40d46e59531c7b14aa03815
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