Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Dennis J. Milanowski"'
Autor:
Xing-Cong Li, Yizhou Liu, Kirk R. Gustafson, Dennis J. Milanowski, Michael T. Davies-Coleman, Josep Saurí, James A. Kelley, Larry A. Walker, R. Thomas Williamson, Shabana I. Khan, Kirill A. Blinov, Heidi R. Bokesch, Naoya Oku, Laura K. Cartner, Yuanqing Ding, Daneel Ferreira, Gary E. Martin, James B. McMahon
Publikováno v:
Chemical Science
Newly described NMR experimental approaches can provide valuable structural details and a complementary means of structure verification.
Ambiguities and errors in the structural assignment of organic molecules hinder both drug discovery and tota
Ambiguities and errors in the structural assignment of organic molecules hinder both drug discovery and tota
Autor:
Ulla Mocek, Peter Kowalenko, Dennis J. Milanowski, Kasi V. Somayajula, Rafael I. San Miguel, Mani Upreti, Indra Prakash
Publikováno v:
Food Chemistry. 131:413-421
Photodegradation of the naturally occurring high-potency sweetener monatin was studied in a lemon–lime beverage model system under simulated conditions. Most of the monatin disappeared after treatment with the equivalent of four days of ultraviolet
Autor:
Grant E. Dubois, Dennis J. Milanowski, Venkata Sai Prakash Chaturvedula, Indra Prakash, Ulla Mocek, John F. Clos, Joshua Rhea
Publikováno v:
Phytochemistry Letters. 4:209-212
From the commercial extract of the leaves of Stevia rebaudiana, three new diterpenoid glycosides were isolated besides eight known steviol glycosides including stevioside, rebaudiosides A–F and dulcoside A. The structures of the three compounds wer
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 55:366-372
Four low-level impurities were detected during the development and scale up of the synthesis of ALB 109564(a). These impurities were isolated and characterized in order to determine how they originated in the drug substance. The information allowed t
Autor:
Michele Luche, D Craig Hopp, Midori Clarke, Joshua Rhea, Dennis J. Milanowski, Khadidja Romari, Linda Francis, Ulla Mocek, Macarena Irigoyen, Daniel Jacobsen, Grant J Carr, Chris Smith, John Rabenstein
Publikováno v:
Journal of Natural Products. 71:2032-2035
Two new xanthone antibiotics, citreamicin delta (1) and epsilon (2), with potent activity against Gram-positive pathogens including multidrug-resistant Staphylococcus aureus (MDRSA) were discovered. Compounds 1 and 2 exhibited MIC values < 1 microg/m
Autor:
D Craig Hopp, John Rabenstein, Linda Francis, Midori Clarke, Dennis J. Milanowski, Ulla Mocek, Michele Luche, Macarena Irigoyen, Khadidja Romari, Grant J Carr, Joshua Rhea, Chris Smith
Publikováno v:
The Journal of Antibiotics. 61:675-679
Resistance to currently available antibiotics has become a widely recognized crisis in the medical community. To address this, many companies and researchers are refocusing their attention towards natural products, which have an excellent track recor
Publikováno v:
Current Medicinal Chemistry -Anti-Infective Agents. 3:233-249
Autor:
Kirk R. Gustafson, Lewis K. Pannell, Mark A. Lipton, Sonja Hess, Edgardo Alvira, Dennis J. Milanowski
Publikováno v:
Journal of Chromatography A. 1035:211-219
Unusual amino acids such as beta-methoxytyrosine (beta-MeOTyr), allo-threonine (allo-Thr) and allo-isoleucine (allo-Ile) were derivatized with N-alpha-(2,4-dinitro-5-fluorophenyl)-L-alaninamide (FDAA), 2,3,4,6-tetra-O-acetyl-beta-D-glucopyranosyl iso
Autor:
Barry R. O'keefe, Mohammad A. Rashid, Michael R. Boyd, Lewis K. Pannell, Dennis J. Milanowski, Joseph P. Nawrocki, Kirk R. Gustafson
Publikováno v:
Journal of Natural Products. 67:441-444
Cyclonellin (1), a new cyclic octapeptide, was isolated from an aqueous extract of the marine sponge Axinella carteri. Its structure was elucidated by interpretation of NMR spectral data of the intact compound and N-terminal Edman sequencing of linea
Autor:
Ulla Mocek, Dennis J. Milanowski, Venkata Sai Prakash Chaturvedula, Indra Prakash, Joshua Rhea
Publikováno v:
Natural product communications. 6(2)
Two new new diterpene glycosides, 13-[(2-O-(6-O-beta-D-glucopyranosyl)-beta-D-glucopyranosyl-beta-D-glucopyranosyl)oxy] kaur-16-en-18-oic acid beta-D-glucopyranosyl ester (1) and 13-[(2-O-beta-D-glucopyranosyl-3-O-beta-D-fructofuranosyl-beta-D-glucop